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D-Index & Metrics

Chemistry

D-Index
49
Citations
7377
World Ranking
14964
National Ranking
3815

Research.com Recognitions

  • 1987 - Fellow of Alfred P. Sloan Foundation

Overview

Marcus A. Tius is affiliated with the University of Hawaii at Manoa in the United States. Their research activity predominantly focuses on the fields of Chemistry and Materials Science, with specialization in Organic Chemistry and Materials Chemistry. The scientist's work also extends into related subfields such as Molecular Biology, Oncology, and Pharmaceutical Science.

Their research topics are centered on several key areas:

  • Synthesis and biological activity
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Synthesis and Catalytic Reactions
  • Synthesis of β-Lactam Compounds
  • Cytokine Signaling Pathways and Interactions
  • Click Chemistry and Applications

Frequent publication venues for Marcus A. Tius include:

  • The Cambridge Structural Database
  • Cancer Research
  • Bioorganic & Medicinal Chemistry Letters
  • Organic Letters
  • Organic & Biomolecular Chemistry

The scientist has collaborated extensively with certain co-authors. Frequent collaborators consist of:

  • Cody F. Dickinson
  • Glenn P. A. Yap
  • Peibin Yue
  • Francisco Lopez-Tapia
  • James Turkson

Among recent publications, notable papers include:

  • "Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors" (2020, Journal of Medicinal Chemistry)
  • "Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancer" (2021, Scientific Reports)
  • "Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo" (2022, Cancer Letters)
  • "Natural product preferentially targets redox and metabolic adaptations and aberrantly active STAT3 to inhibit breast tumor growth in vivo" (2022, Cell Death and Disease)
  • "The Chemistry of Phytoplankton" (2024, Chemical Reviews)

Marcus A. Tius was awarded the title of Fellow of the Alfred P. Sloan Foundation in 1987.

Best Publications

  • Some New Nazarov Chemistry

    Marcus A. Tius

  • Cationic cyclopentannelation of allene ethers.

    Marcus A. Tius

  • Asymmetric Nazarov Cyclizations.

    Naoyuki Shimada;Craig Stewart;Marcus A. Tius

  • Total Synthesis of Cryptophycins. Revision of the Structures of Cryptophycins A and C

    Russell A. Barrow;Thomas Hemscheidt;Jian Liang;Seunguk Paik

  • Allene ether Nazarov cyclization

    Marcus A. Tius

  • Xenon difluoride in synthesis

    Marcus A. Tius

  • Synthesis and absolute stereochemistry of roseophilin.

    Paul E. Harrington;Marcus A. Tius

  • Total synthesis of (.+-.)-aphidicolin

    E. J. Corey;Marcus A. Tius;Jagabandhu Das

  • C-Glycosylanthraquinone synthesis: total synthesis of vineomycinone B2 methyl ester

    Marcus A. Tius;Jorge Gomez-Galeno;Xue Qin Gu;Javid H. Zaidi

  • Catalytic Enantioselective Nazarov Cyclization: Construction of Vicinal All‐Carbon‐Atom Quaternary Stereocenters

    Anais Jolit;Patrick M. Walleser;Glenn P. A. Yap;Marcus A. Tius;Marcus A. Tius

  • An organocatalytic asymmetric Nazarov cyclization.

    Ashok K. Basak;Naoyuki Shimada;William F. Bow;David A. Vicic

  • Synthesis of cembranes and cembranolides

    Marcus A. Tius

  • Unsaturated Side Chain β-11-Hydroxyhexahydrocannabinol Analogs

    J Busch-Petersen;W A Hill;P Fan;A Khanolkar

  • Copper(I)-catalyzed reactions of .beta.,.gamma.-epoxy alcohols with Grignard reagents

    Marcus A. Tius;Abdul H. Fauq

  • The palladium(II)-catalyzed Nazarov reaction.

    Cisco Bee;Eric Leclerc;Marcus A. Tius

  • Asymmetric amine-intercepted Nazarov cyclization.

    Francis Dhoro;Tor E. Kristensen;Vegar Stockmann;Glenn P. A. Yap

  • A novel approach to the synthesis of morphine alkaloids: the synthesis of (d,l)-thebainone-A

    Marcus A. Tius;Michael A. Kerr

  • Classical/Nonclassical Hybrid Cannabinoids: Southern Aliphatic Chain-Functionalized C-6β Methyl, Ethyl, and Propyl Analogues

    David J. Drake;Rader S. Jensen;Jakob Busch-Petersen;Joel K. Kawakami

  • A Formal Total Synthesis of Roseophilin: Cyclopentannelation Approach to the Macrocyclic Core

    Paul E. Harrington;Marcus A. Tius

  • Enamine-Iminium Ion Nazarov Cyclization of α-Ketoenones

    William F. Bow;Ashok K. Basak;Anais Jolit;David A. Vicic

Frequent Co-Authors

Alexandros Makriyannis
Alexandros Makriyannis Northeastern University
Richard E. Moore
Richard E. Moore University of Hawaii at Manoa
Glenn P. A. Yap
Glenn P. A. Yap University of Delaware
David A. Vicic
David A. Vicic Lehigh University
Michael A. Kerr
Michael A. Kerr University of Western Ontario
E. J. Corey
E. J. Corey Harvard University
Gregory M. L. Patterson
Gregory M. L. Patterson University of Hawaii at Manoa
Shmuel Carmeli
Shmuel Carmeli Tel Aviv University
Bakthan Singaram
Bakthan Singaram University of California, Santa Cruz
Arthur B. Pardee
Arthur B. Pardee Harvard University

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