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Frederick G. West

Frederick G. West

D-Index & Metrics

Chemistry

D-Index
51
Citations
6943
World Ranking
14196
National Ranking
383

Overview

Frederick G. West is affiliated with the University of Alberta in Canada and has contributed extensively to research in the intersecting fields of Biochemistry, Genetics and Molecular Biology, Chemistry, and Medicine. Their work encompasses a broad range of topics within these disciplines, often focusing on areas such as Organic Chemistry, Molecular Biology, Materials Chemistry, Oncology, and Epidemiology.

West's scholarly output includes numerous publications in specialized venues. Frequent journals for publishing include:

  • The Cambridge Structural Database
  • Pharmaceutics
  • Organic Letters
  • Organic & Biomolecular Chemistry
  • European Journal of Organic Chemistry

The scientist has contributed to several research topics, prominently:

  • Cancer, Hypoxia, and Metabolism
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Cyclization and Aryne Chemistry
  • Catalytic Alkyne Reactions
  • DNA Repair Mechanisms
  • Cancer therapeutics and mechanisms

Frederick G. West's published articles cover a variety of specialized subjects. Selected recent papers include:

  • "A Mild Method for the Generation and Interception of 1,2-Cycloheptadienes with 1,3-Dipoles" (2020) published in Organic Letters
  • "Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition" (2021) published in Scientific Reports
  • "Pharmacological targets and emerging treatments for respiratory syncytial virus bronchiolitis" (2020) published in Pharmacology & Therapeutics
  • "Generation and trapping of electron-deficient 1,2-cyclohexadienes. Unexpected hetero-Diels-Alder reactivity" (2020) published in Organic & Biomolecular Chemistry
  • "Enhancing the activity of platinum-based drugs by improved inhibitors of ERCC1-XPF-mediated DNA repair" (2021) published in Cancer Chemotherapy and Pharmacology

Collaboration is a consistent aspect of West's research, with frequent co-authorship ties including:

  • Frank Wuest
  • Michael Weinfeld
  • Ahmed H. Elmenoufy
  • David Jay
  • Jack A. Tuszyński

Best Publications

  • Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations

    Tina N. Grant;Curtis J. Rieder;Frederick G. West

  • Recent advances in the Stevens rearrangement of ammonium ylides. Application to the synthesis of alkaloid natural products

    John A. Vanecko;Hayley Wan;Frederick G. West

  • Ylides by the desilylation of .alpha.-silyl onium salts

    Edwin Vedejs;Frederick G. West

  • New efficient iterative approaches to polycyclic ethers.

    Fredrik P. Marmsäter;Frederick G. West

  • Advances in the Nazarov cyclization.

    Waka Nakanishi;Frederick G West

  • Comprehensive in vitro characterization of PD-L1 small molecule inhibitors

    Aravindhan Ganesan;Marawan Ahmed;Isobel Okoye;Elena Arutyunova

  • The total synthesis of a natural cardenolide: (+)-digitoxigenin

    Gilbert Stork;Fred West;Hee Yoon Lee;Hee Yoon Lee;Richard C. A. Isaacs

  • Profound Catalyst Effects in the Generation and Reactivity of Carbenoid-Derived Cyclic Ylides

    F. G. West;B. N. Naidu;Richland W. Tester

  • The Stevens [1,2]-Shift of Oxonium Ylides: A Route to Substituted Tetrahydrofuranones

    T. H. Eberlein;F. G. West;R. W. Tester

  • Chirality Transfer from Carbon to Nitrogen to Carbon via Cyclic Ammonium Ylides

    Kevin W. Glaeske and;F. G. West

  • PREPARATION AND SYNTHETIC APPLICATIONS OF AZETIDINES (Dedicated to Dr. Albert Padwa on his 75th birthday)

    Tina M. Bott;F. G. West

  • Nonstabilized imidate ylides by the desilylation method: a route to the pyrrolizidine alkaloids retronecine and indicine

    Edwin Vedejs;Scott Larsen;Frederick G. West

  • A NOVEL CYCLOISOMERIZATION OF TETRAENONES : 4+3 TRAPPING OF THE NAZAROV OXYALLYL INTERMEDIATE

    Yong Wang;and Atta M. Arif;F. G. West

  • Formal intermolecular 4 + 4 approach to cyclooctanoids: 4 + 3 capture of the Nazarov oxyallyl intermediate with simple 1,3-dienes.

    Yong Wang;Brenden D. Schill;and Atta M. Arif;F. G. West

  • A new approach to the nazarov reaction via sequential electrocyclic ring opening and ring closure

    Tina N. Grant;F. G. West

  • New route to substituted piperidines via the Stevens [1,2]-shift of ammonium ylides

    F. G. West;B. N. Naidu

  • Piperidines via Ammonium Ylide [1,2]-Shifts: A Concise, Enantioselective Route to (-)-Epilupinine from Proline Ester

    F. G. West;B. N. Naidu

  • Synthesis and characterization of fluorescent cobalamin (CobalaFluor) derivatives for imaging.

    Claudia C. Smeltzer;Michelle J. Cannon;Patrick R. Pinson;John D. Munger

  • Ionic Hydrogenation of Oxyallyl Intermediates: The Reductive Nazarov Cyclization

    Sören Giese;F.G. West

  • Intermolecular Trapping of the Nazarov Intermediate: Domino Electrocyclization/[3+2] Cycloadditions with Allylsilanes

    Sören Giese;Lars Kastrup;Dirk Stiens;Frederick G. West

Frequent Co-Authors

Robert McDonald
Robert McDonald University of Alberta
Atta M. Arif
Atta M. Arif University of Utah
Michael Weinfeld
Michael Weinfeld University of Alberta
Richard D. Ernst
Richard D. Ernst University of Utah
Michael J. Ferguson
Michael J. Ferguson University of Alberta
Edwin Vedejs
Edwin Vedejs University of Michigan–Ann Arbor
Brian D. Sykes
Brian D. Sykes University of Alberta
Michael Houghton
Michael Houghton University of Alberta
David H. Alpers
David H. Alpers Washington University in St. Louis
David Westaway
David Westaway University of Alberta

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