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Chemistry

D-Index
57
Citations
8784
World Ranking
11388
National Ranking
3086

Research.com Recognitions

  • 2010 - Ernest Guenther Award, American Chemical Society (ACS)
  • 2004 - Herty Medal, American Chemical Society (ACS)
  • 1986 - Fellow of Alfred P. Sloan Foundation

Overview

Michael T. Crimmins is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focuses on the fields of Chemistry and Biochemistry, Genetics, and Molecular Biology. More specifically, their work concentrates on Organic Chemistry, Pharmacology, Molecular Biology, Biotechnology, and Biochemistry.

The main topics highlighted in their research include Synthetic Organic Chemistry Methods, Chemical synthesis and alkaloids, Oxidative Organic Chemistry Reactions, Marine Sponges and Natural Products, Microbial Natural Products and Biosynthesis, Axial and Atropisomeric Chirality Synthesis, and Traditional and Medicinal Uses of Annonaceae.

Michael T. Crimmins has contributed publications to several venues with notable frequency. These include OPAL (Open@LaTrobe) hosted by La Trobe University, where they published 16 papers, UNC Libraries with 7 papers, The Journal of Organic Chemistry with 1 paper, and HAL (Le Centre pour la Communication Scientifique Directe) with 1 paper.

Their recent research papers include the following:

  • The Discreet Structural Diversity of Briarellins: DU8+ Guided Multiple Structure Revisions Yielded Two Unknown Structural Types (2020, The Journal of Organic Chemistry)
  • Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research (2025, HAL (Le Centre pour la Communication Scientifique Directe))
  • Total Synthesis of Apoptolidin A (2020, OPAL (Open@LaTrobe) (La Trobe University))
  • A Highly Convergent Approach toward (−)-Brevenal (2020, OPAL (Open@LaTrobe) (La Trobe University))
  • Total Synthesis of Brevetoxin A (2020, OPAL (Open@LaTrobe) (La Trobe University))

Frequent collaborators in their research efforts include Andrei G. Kutateladze, J. Lucas Zuccarello, Patrick J. McDougall, D. Sai Reddy, and Abimael D. Rodríquez.

Throughout their career, Michael T. Crimmins has received several awards. These include the Ernest Guenther Award from the American Chemical Society (ACS) in 2010, the Herty Medal from ACS in 2004, and a fellowship from the Alfred P. Sloan Foundation in 1986.

Best Publications

  • Asymmetric aldol additions: use of titanium tetrachloride and (-)-sparteine for the soft enolization of N-acyl oxazolidinones, oxazolidinethiones, and thiazolidinethiones.

    Michael T. Crimmins;Bryan W. King;Elie A. Tabet;Kleem Chaudhary

  • New developments in the enantioselective synthesis of cyclopentyl carbocyclic nucleosides

    Michael T. Crimmins

  • Synthetic Applications of Intramolecular Enone-Olefin Photocycloadditions

    Michael T. Crimmins

  • Asymmetric Aldol Additions with Titanium Enolates of Acyloxazolidinethiones: Dependence of Selectivity on Amine Base and Lewis Acid Stoichiometry

    Michael T. Crimmins;Bryan W. King;Elie A. Tabet

  • Titanium Enolates of Thiazolidinethione Chiral Auxiliaries: Versatile Tools for Asymmetric Aldol Additions

    Michael T. Crimmins;Kleem Chaudhary

  • An Efficient Asymmetric Approach to Carbocyclic Nucleosides: Asymmetric Synthesis of 1592U89, a Potent Inhibitor of HIV Reverse Transcriptase

    Michael T. Crimmins;Bryan W. King

  • An Asymmetric Aldol−Ring-Closing Metathesis Strategy for the Enantioselective Construction of Oxygen Heterocycles: An Efficient Approach to the Enantioselective Synthesis of (+)-Laurencin

    Michael T. Crimmins;Allison L. Choy

  • Protocols for the preparation of each of the four possible stereoisomeric α-alkyl-β-hydroxy carboxylic acids from a single chiral aldol reagent

    Nanine A. Van Draanen;Simeon Arseniyadis;Michael T. Crimmins;Clayton H. Heathcock

  • An efficient, general asymmetric synthesis of carbocyclic nucleosides: Application of an asymmetric aldol/ring-closing metathesis strategy

    Michael T. Crimmins;Bryan W. King;William J. Zuercher;Allison L. Choy

  • Total Synthesis of (+)-Laurencin: An Asymmetric Alkylation−Ring-Closing Metathesis Approach to Medium Ring Ethers

    Michael T. Crimmins;Kyle A. Emmitte

  • Total Synthesis of (+)-Prelaureatin and (+)-Laurallene

    Michael T. Crimmins;Elie A. Tabet

  • Asymmetric Aldol−Ring-Closing Metathesis Strategy for the Enantioselective Construction of Six- to Nine-Membered Oxygen Heterocycles

    Michael T. Crimmins;Allison L. Choy

  • Asymmetric Total Synthesis of Callystatin A: Asymmetric Aldol Additions with Titanium Enolates of Acyloxazolidinethiones

    Michael T. Crimmins;Bryan W. King

  • The Total Synthesis of (±)-Ginkgolide B

    Michael T. Crimmins;Jennifer M. Pace;Philippe G. Nantermet;Agnes S. Kim-Meade

  • Diastereoselective Alkylations of Oxazolidinone Glycolates: A Useful Extension of the Evans Asymmetric Alkylation

    Michael T. Crimmins;Kyle A. Emmitte;Jason D. Katz

  • Asymmetric total synthesis of spongistatins 1 and 2.

    Michael T. Crimmins;Jason D. Katz;David G. Washburn;Shawn P. Allwein

  • Enantioselective total synthesis of bistramide A.

    Michael T. Crimmins;Amy C. DeBaillie

  • The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research

    James B. McAlpine;Shao Nong Chen;Andrei Kutateladze;John B. Macmillan

  • Highly selective acetate aldol additions using mesityl-substituted chiral auxiliaries.

    Michael T. Crimmins;Mariam Shamszad

  • Asymmetric total synthesis of (-)-isolaurallene.

    Michael T. Crimmins;Kyle A. Emmitte

  • Total Synthesis of Brevetoxin A

    Michael T. Crimmins;J. Lucas Zuccarello;J. Michael Ellis;Patrick J. McDougall

Frequent Co-Authors

Hiroyuki Koshino
Hiroyuki Koshino Tokyo University of Agriculture
Clayton H. Heathcock
Clayton H. Heathcock University of California, Berkeley
Bradley S. Moore
Bradley S. Moore University of California, San Diego
William H. Gerwick
William H. Gerwick University of California, San Diego
Ben Shen
Ben Shen Scripps Research Institute
Michael F. Summers
Michael F. Summers University of Maryland, Baltimore County
Ronald J. Quinn
Ronald J. Quinn Griffith University
Nicholas H. Oberlies
Nicholas H. Oberlies University of North Carolina at Greensboro
Robert Verpoorte
Robert Verpoorte Leiden University
Young Hae Choi
Young Hae Choi Leiden University

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