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Biology and Biochemistry

D-Index
44
Citations
9234
World Ranking
19236
National Ranking
1493

Overview

Martin D. Ryan is affiliated with the University of St Andrews in the United Kingdom. Their research primarily spans the fields of Medicine and Agricultural and Biological Sciences, with a focus on subfields such as Infectious Diseases, Cardiology and Cardiovascular Medicine, Immunology, Oncology, and Agronomy and Crop Science.

The scientist's work covers several main topics, including:

  • Viral gastroenteritis research and epidemiology
  • Viral Infections and Immunology Research
  • Animal Disease Management and Epidemiology
  • Vector-Borne Animal Diseases
  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses
  • Immune Response and Inflammation

Martin D. Ryan has coauthored with several frequent collaborators, including:

  • Garry A. Luke
  • Fiona Tulloch
  • Lidia Lasecka-Dykes
  • Peter Simmonds
  • Paolo Ribeca

Their research has been published in a variety of scientific journals, with repeated appearances in:

  • The Journal of Immunology
  • Journal of Health Care for the Poor and Underserved
  • Scientific Reports
  • Journal of Applied Microbiology
  • Water

Selected recent papers include:

  • "A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System," 2020, The Journal of Immunology
  • "Colorectal Cancer Screening with Mailed Fecal Immunochemical Tests and Telephone Outreach at a Community Health Center during the COVID-19 Pandemic," 2022, Journal of Health Care for the Poor and Underserved
  • "Immunogenicity of a secreted, C-terminally truncated, form of bovine viral diarrhea virus E2 glycoprotein as a potential candidate in subunit vaccine development," 2023, Scientific Reports
  • "Expression and immunogenicity of secreted forms of bovine ephemeral fever virus glycoproteins applied to subunit vaccine development," 2021, Journal of Applied Microbiology
  • "Insights into Gastrointestinal Virome: Etiology and Public Exposure," 2021, Water

Best Publications

  • Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'.

    Michelle L. L. Donnelly;Garry Luke;Amit Mehrotra;Xuejun Li

  • The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences.

    Michelle L. L. Donnelly;Lorraine E. Hughes;Garry Luke;Heidi Mendoza

  • Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence.

    Martin D. Ryan;Andrew M. Q. King;G. Paul Thomas

  • Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein.

    M D Ryan;J Drew

  • E unum pluribus: multiple proteins from a self-processing polyprotein

    Pablo de Felipe;Garry A. Luke;Lorraine E. Hughes;David Gani

  • Virus-encoded proteinases of the picornavirus super-group.

    Martin D. Ryan;Mike Flint

  • Differentiating infection from vaccination in foot-and-mouth disease using a panel of recombinant, non-structural proteins in ELISA

    D. K. J. Mackay;M. A. Forsyth;P. R. Davies;A. Berlinzani

  • The cleavage activities of aphthovirus and cardiovirus 2A proteins.

    Michelle L. L. Donnelly;David Gani;Mike Flint;Susan Monaghan

  • Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide.

    Pablo de Felipe;Lorraine E. Hughes;Martin D. Ryan;Jeremy D. Brown

  • Site-specific release of nascent chains from ribosomes at a sense codon

    Victoria A. Doronina;Cheng Wu;Pablo de Felipe;Matthew S. Sachs

  • Effects of Foot-and-Mouth Disease Virus Nonstructural Proteins on the Structure and Function of the Early Secretory Pathway: 2BC but Not 3A Blocks Endoplasmic Reticulum-to-Golgi Transport

    Katy Moffat;Gareth Howell;Caroline Knox;Graham J. Belsham

  • Self-processing 2A-polyproteins--a system for co-ordinate expression of multiple proteins in transgenic plants.

    Claire Halpin;Susan E. Cooke;Abdellah Barakate;Abdel El Amrani

  • Occurrence, function and evolutionary origins of ‘2A-like’ sequences in virus genomes

    Garry A. Luke;Pablo de Felipe;Alexander Lukashev;Susanna E. Kallioinen

  • A case for "StopGo": reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go).

    John F. Atkins;Norma M. Wills;Gary Loughran;Chih Yu Wu

  • RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies

    Fiona Tulloch;Nicky J Atkinson;David J Evans;Martin D Ryan

  • Specificity of enzyme-substrate interactions in foot-and-mouth disease virus polyprotein processing

    Martin D. Ryan;Graham J. Belsham;Andrew M.Q. King

  • 2A peptides provide distinct solutions to driving stop-carry on translational recoding

    Pamila Sharma;Fu Yan;Victoria A. Doronina;Helena Escuin-Ordinas

  • Inhibition of the Secretory Pathway by Foot-and-Mouth Disease Virus 2BC Protein Is Reproduced by Coexpression of 2B with 2C, and the Site of Inhibition Is Determined by the Subcellular Location of 2C

    Katy Moffat;Caroline Knox;Gareth Howell;Sarah J. Clark

  • Targeting of proteins derived from self-processing polyproteins containing multiple signal sequences.

    Pablo de Felipe;Martin D. Ryan

  • Site-Specific Release of Nascent Chains from Ribosomes at

    Victoria A. Doronina;Cheng Wu;Pablo de Felipe;Matthew S. Sachs

Frequent Co-Authors

Claire Halpin
Claire Halpin University of Dundee
Graham J. Belsham
Graham J. Belsham University of Copenhagen
Thomas Wileman
Thomas Wileman University of East Anglia
John F. Atkins
John F. Atkins University College Cork
Peter Simmonds
Peter Simmonds University of Oxford
Matthew S. Sachs
Matthew S. Sachs Texas A&M University
David J.A. Evans
David J.A. Evans Durham University
Fred Brown
Fred Brown United States Department of Agriculture
Nick J. Knowles
Nick J. Knowles The Pirbright Institute
Jeffrey W. Almond
Jeffrey W. Almond Sanofi (France)

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