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Richard Wade-Martins

Richard Wade-Martins

D-Index & Metrics

Genetics

D-Index
66
Citations
33344
World Ranking
2566
National Ranking
328

Overview

Richard Wade-Martins is affiliated with the University of Oxford in the United Kingdom. Their research primarily spans the fields of medicine, neuroscience, and biochemistry, genetics, and molecular biology, with specific focus on neurology, cellular and molecular neuroscience, molecular biology, physiology, and epidemiology.

The scientist's main topics of study include:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Autophagy in Disease and Therapy
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Genetic Neurodegenerative Diseases
  • Neuroscience and Neural Engineering

Frequent co-authors collaborating with Richard Wade-Martins include:

  • Nora Bengoa-Vergniory
  • Brent J. Ryan
  • Natalie Connor-Robson
  • Sally A. Cowley
  • Bryan Ng

The scientist regularly publishes in a range of venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Alzheimer s & Dementia
  • Nature Communications
  • Scientific Reports

Some representative recent papers include:

  • Mitochondrial Dysfunction and Mitophagy in Parkinson's Disease: From Mechanism to Therapy, 2020, Trends in Biochemical Sciences
  • A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders, 2020, Nature Communications
  • Impaired dopamine release in Parkinson's disease, 2023, Brain
  • "LRRK2: Autophagy and Lysosomal Activity", 2020, Frontiers in Neuroscience
  • Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases, 2021, International Journal of Molecular Sciences

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

    W Haenseler;S N Sansom;J Buchrieser;S E Newey

  • Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease.

    Brent J. Ryan;Selim Hoek;Edward A. Fon;Richard Wade-Martins

  • The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

    Heather D.E. Booth;Warren D. Hirst;Richard Wade-Martins

  • LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

    Javier Alegre-Abarrategui;Helen Christian;Michele M.P. Lufino;Ruxandra Mutihac

  • LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia

    Clyde Francks;S. Maegawa;J. Laurén;B. S. Abrahams

  • Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation

    Olivia A Shipton;Julie R Leitz;Jenny Dworzak;Christine E J Acton

  • ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

    Hugo J.R. Fernandes;Elizabeth M. Hartfield;Helen C. Christian;Evangelia Emmanoulidou

  • The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration

    Silvia Paracchini;Ankur Thomas;Sandra Castro;Cecilia Lai

  • α-Synuclein and dopamine at the crossroads of Parkinson's disease

    Lara Lourenço Venda;Stephanie J. Cragg;Vladimir L. Buchman;Richard Wade-Martins

  • The influence of age and gender on motor and non-motor features of early Parkinson's disease: Initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort

    Konrad Szewczyk-Krolikowski;Paul Tomlinson;Kannan Nithi;Richard Wade-Martins

  • R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.

    Matthias Groh;Michele M. P. Lufino;Richard Wade-Martins;Natalia Gromak

  • Alpha-synuclein oligomers: a new hope

    Nora Bengoa-Vergniory;Rosalind F. Roberts;Richard Wade-Martins;Javier Alegre-Abarrategui

  • Mitochondrial Dysfunction and Mitophagy in Parkinson's Disease: From Mechanism to Therapy.

    Ana Belen Malpartida;Matthew Williamson;Derek P. Narendra;Richard Wade-Martins

  • C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

    Ruxandra Dafinca;Jakub Scaber;Nida'a Ababneh;Tatjana Lalic

  • Targeting Alpha-Synuclein as a Therapy for Parkinson's Disease.

    Carroll Rutherford Fields;Nora Bengoa-Vergniory;Richard Wade-Martins

  • A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

    Devika Agarwal;Devika Agarwal;Cynthia Sandor;Viola Volpato;Tara M. Caffrey;Tara M. Caffrey

  • Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain

    Rosalind F. Roberts;Richard Wade-Martins;Javier Alegre-Abarrategui

  • Functional Alterations to the Nigrostriatal System in Mice Lacking All Three Members of the Synuclein Family

    S Anwar;O Peters;S Millership;N Ninkina

Frequent Co-Authors

Sally A. Cowley
Sally A. Cowley University of Oxford
Michele T.M. Hu
Michele T.M. Hu University of Oxford
Kevin Talbot
Kevin Talbot University of Oxford
Keith M. Channon
Keith M. Channon University of Oxford
Stephanie J. Cragg
Stephanie J. Cragg University of Oxford
Caleb Webber
Caleb Webber University of Oxford
William James
William James University of Oxford
Javier Díaz-Nido
Javier Díaz-Nido Spanish National Research Council
David M. Bannerman
David M. Bannerman University of Oxford
Clare E. Mackay
Clare E. Mackay University of Oxford

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