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Biology and Biochemistry

D-Index
66
Citations
14609
World Ranking
8721
National Ranking
670

Overview

William James is affiliated with the University of Oxford in the United Kingdom and primarily conducts research within the field of Medicine. Their work notably spans subfields including Infectious Diseases, Molecular Biology, Immunology, Neurology, and Public Health, Environmental and Occupational Health. The scientist's research covers a range of critical topics such as SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Neuroinflammation and Neurodegeneration Mechanisms, Mosquito-borne diseases and control, Monoclonal and Polyclonal Antibodies Research, SARS-CoV-2 detection and testing, and Immune cells in cancer.

William James has published extensively, with a number of recent papers focusing on SARS-CoV-2 variants and neutralization mechanisms. Notable publications include:

  • Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera, 2021, Cell
  • Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2, 2020, Nature Structural & Molecular Biology
  • Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera, 2021, Cell
  • The antigenic anatomy of SARS-CoV-2 receptor binding domain, 2021, Cell
  • Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient, 2020, Nature Structural & Molecular Biology

Their frequent coauthors include Javier Gilbert-Jaramillo, Tiong Kit Tan, Miles W. Carroll, Alain Townsend, and Sally A. Cowley, establishing collaborative work patterns in their research endeavors.

William James's publications appear predominantly in high-impact and specialized scientific venues. The most common publication outlets are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • SSRN Electronic Journal
  • Nature Communications
  • Nature Structural & Molecular Biology

The focus and volume of publications in Infectious Diseases reflect a sustained commitment to understanding disease mechanisms and immune responses. The diverse range of topics emphasizes research on SARS-CoV-2 variants, immune system interactions, and neuroinflammatory processes linked to infectious agents.

Best Publications

  • Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera.

    D Zhou;W Dejnirattisai;P Supasa;C Liu

  • Neurological manifestations of dengue infection.

    Tom Solomon;Nguyen Minh Dung;David W Vaughn;Rachel Kneen;Rachel Kneen

  • A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

    W Haenseler;S N Sansom;J Buchrieser;S E Newey

  • Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.

    J Huo;J Huo;A Le Bas;A Le Bas;R R Ruza;Duyvesteyn Hme.

  • Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera.

    P Supasa;D Zhou;W Dejnirattisai;C Liu

  • The antigenic anatomy of SARS-CoV-2 receptor binding domain.

    Wanwisa Dejnirattisai;Daming Zhou;Helen M. Ginn;Helen M.E. Duyvesteyn

  • ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

    Hugo J.R. Fernandes;Elizabeth M. Hartfield;Helen C. Christian;Evangelia Emmanoulidou

  • Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species

    S. L. Pearce;D. F. Clarke;D. F. Clarke;P. D. East;S. Elfekih

  • Resistance to the Cry1Ac δ-Endotoxin of Bacillus thuringiensis in the Cotton Bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae)

    Raymond Joseph Akhurst;William James;Lisa Jane Bird;Cheryl Beard

  • Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.

    D Zhou;Duyvesteyn Hme.;Chen C-P.;Huang C-G.;Huang C-G.

  • Characterization of 2 '-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion

    Alexandre Rhie;Louise Kirby;Natalie Sayer;Rosanna Wellesley

  • Neutralization of Infectivity of Diverse R5 Clinical Isolates of Human Immunodeficiency Virus Type 1 by gp120-Binding 2′F-RNA Aptamers

    Makobetsa Khati;Michael Schüman;Jamal Ibrahim;Quentin Sattentau

  • The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding.

    P B Fischer;M Collin;G B Karlsson;W James

  • Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3

    Karl R. Karlsson;Sally Cowley;Fernando O. Martinez;Michael Shaw

  • Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages.

    Julian Buchrieser;William James;Michael D. Moore

  • OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand.

    A al-Shamkhani;M L Birkeland;M Puklavec;M H Brown

  • Physiological characterisation of human iPS-derived dopaminergic neurons.

    Elizabeth M. Hartfield;Michiko Yamasaki-Mann;Hugo J. Ribeiro Fernandes;Jane Vowles

  • HIV entry in macrophages is dependent on intact lipid rafts.

    Gemma C. Carter;Laura Bernstone;Dhaval Sangani;Jessica Wynter Bee

  • Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site.

    Mark P. Ashe;Philip Griffin;William James;Nick J. Proudfoot

  • Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination.

    Alexandre Teixeira;Abdessamad Tahiri-Alaoui;Steve West;Benjamin Thomas

Frequent Co-Authors

Sally A. Cowley
Sally A. Cowley University of Oxford
Alain Townsend
Alain Townsend University of Oxford
Miles W. Carroll
Miles W. Carroll University of Oxford
Paul Klenerman
Paul Klenerman University of Oxford
Juthathip Mongkolsapaya
Juthathip Mongkolsapaya University of Oxford
Jingshan Ren
Jingshan Ren University of Oxford
David I. Stuart
David I. Stuart University of Oxford
Raymond J. Owens
Raymond J. Owens University of Oxford
James H. Naismith
James H. Naismith Rosalind Franklin Institute
Richard Wade-Martins
Richard Wade-Martins University of Oxford

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