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John P. Overington

John P. Overington

D-Index & Metrics

Computer Science

D-Index
51
Citations
29994
World Ranking
5193
National Ranking
311

Overview

John P. Overington is affiliated with Exscientia in the United Kingdom and focuses their research primarily in the field of Medicine. Their work covers several specialized subfields including Molecular Biology, Computational Theory and Mathematics, Epidemiology, Spectroscopy, and Surgery.

Their recent publications address diverse topics within healthcare and computational sciences. Notable papers include:

  • PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease, 2020, Cochrane Database of Systematic Reviews
  • Artificial intelligence, drug repurposing and peer review, 2020, Nature Biotechnology
  • AI3SD Interview with Professor John Overington, 2020, ePrints Soton (University of Southampton)
  • EXTH-46. ARTIFICIAL INTELLIGENCE-BASED IDENTIFICATION OF COMBINED VANDETANIB AND EVEROLIMUS IN THE TREATMENT OF ACVR1-MUTANT DIFFUSE INTRINSIC PONTINE GLIOMA, 2020, Neuro-Oncology
  • AI3SD Video: Drug Repositioning for COVID-19, 2020, ePrints Soton (University of Southampton)

Frequent co-authors collaborating with Overington include:

  • Amand F. Schmidt
  • John-Paul Carter
  • Lucy S Pearce
  • John T. Wilkins
  • Aroon D. Hingorani

Their research has been published mostly in the following venues:

  • ePrints Soton (University of Southampton)
  • Cochrane Database of Systematic Reviews
  • Nature Biotechnology
  • Neuro-Oncology
  • SSRN Electronic Journal

Key topics addressed in Overington's work span multiple aspects of healthcare and computational methods, such as:

  • Computational Drug Discovery Methods
  • Lipoproteins and Cardiovascular Health
  • Pharmaceutical Economics and Policy
  • Artificial Intelligence in Healthcare and Education
  • Misinformation and Its Impacts
  • Academic Publishing and Open Access
  • Glioma Diagnosis and Treatment

Best Publications

  • How many drug targets are there

    John P. Overington;Bissan Al-Lazikani;Andrew L. Hopkins

  • ChEMBL: a large-scale bioactivity database for drug discovery

    Anna Gaulton;Louisa J. Bellis;A. Patricia Bento;Jon Chambers

  • A comprehensive map of molecular drug targets

    Rita Santos;Rita Santos;Oleg Ursu;Anna Gaulton;A. Patrícia Bento

  • The ChEMBL database in 2017.

    Anna Gaulton;Anne Hersey;Michał Nowotka;A. Patrícia Bento

  • The ChEMBL bioactivity database: an update

    A. Patrícia Bento;Anna Gaulton;Anne Hersey;Louisa J. Bellis

  • An atlas of genetic influences on human blood metabolites

    So-Youn Shin;Eric B Fauman;Ann-Kristin Petersen;Jan Krumsiek

  • The druggable genome and support for target identification and validation in drug development.

    Chris Finan;Anna Gaulton;Felix A. Kruger;R. Thomas Lumbers

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • ChEMBL web services: streamlining access to drug discovery data and utilities.

    Mark Davies;Michal Nowotka;George Papadatos;Nathan Dedman

  • HOMSTRAD: A database of protein structure alignments for homologous families

    Kenji Mizuguchi;Charlotte M. Deane;Tom L. Blundell;John P. Overington

  • Can we rationally design promiscuous drugs

    Andrew L Hopkins;Jonathan S Mason;John P Overington

  • JOY: protein sequence-structure representation and analysis.

    Kenji Mizuguchi;Charlotte M. Deane;Tom L. Blundell;Mark S. Johnson

  • Unexplored therapeutic opportunities in the human genome.

    Tudor I. Oprea;Cristian G. Bologa;Søren Brunak;Allen Campbell

  • A structural basis for sequence comparisons : an evaluation of scoring methodologies

    Mark S. Johnson;John P. Overington

  • Derivation of rules for comparative protein modeling from a database of protein structure alignments

    Andrej ŠAli;John P. Overington

  • Genomic-scale prioritization of drug targets: the TDR Targets database

    Fernán Agüero;Bissan Al-Lazikani;Martin Aslett;Matthew Berriman

  • Comprehensive characterization of the Published Kinase Inhibitor Set

    Jonathan M. Elkins;Vita Fedele;Marta Szklarz;Kamal R. Abdul Azeez

  • 18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design

    Tom Blundell;Devon Carney;Stephen Gardner;Fiona Hayes

  • PSICQUIC and PSISCORE: accessing and scoring molecular interactions

    Bruno Aranda;Hagen Blankenburg;Samuel Kerrien;Fiona S L Brinkman

  • Pharos: Collating protein information to shed light on the druggable genome

    Dac-Trung Nguyen;Stephen L. Mathias;Cristian Bologa;Søren Brunak

Frequent Co-Authors

Tom L. Blundell
Tom L. Blundell University of Cambridge
Andrej Sali
Andrej Sali University of California, San Francisco
Jonathan B. Baell
Jonathan B. Baell Monash University
Stuart A. Ralph
Stuart A. Ralph University of Melbourne
Guri Giaever
Guri Giaever University of British Columbia
Sergio Wittlin
Sergio Wittlin Swiss Tropical and Public Health Institute
Corey Nislow
Corey Nislow University of British Columbia
Vicky M. Avery
Vicky M. Avery Griffith University
Kiaran Kirk
Kiaran Kirk Australian National University
Elizabeth A. Winzeler
Elizabeth A. Winzeler University of California, San Diego

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