World's Best Scientists 2026 revealed!
Kathleen M. Sakamoto

Kathleen M. Sakamoto

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
13235
World Ranking
16508
National Ranking
6835

Overview

Kathleen M. Sakamoto is affiliated with Stanford University in the United States. Their research spans several domains within medicine and biochemistry, genetics, and molecular biology, with a strong focus on hematology and cancer-related studies.

Their recent publications demonstrate engagement with cutting-edge topics in oncology and hematology, including:

  • GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity (2021, Cancer Cell)
  • Delayed cancer diagnoses and high mortality in children during the COVID-19 pandemic (2020, Pediatric Blood & Cancer)
  • Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia (2021, Blood)
  • Metabolomics in acute myeloid leukemia (2020, Molecular Genetics and Metabolism)
  • RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit (2020, Oncotarget)

Kathleen M. Sakamoto has frequent co-authorship collaborations with:

  • Norman J. Lacayo (23 co-authored papers)
  • Mark C. Wilkes (17 co-authored papers)
  • Hee-Don Chae (12 co-authored papers)
  • Nobuko Hijiya (10 co-authored papers)
  • Anupama Narla (10 co-authored papers)

The scientist commonly publishes in the following venues:

  • Blood (22 publications)
  • Cancer Research (5 publications)
  • Cancers (4 publications)
  • Experimental Hematology (4 publications)
  • Nature Communications (3 publications)

Main fields of study covered by Kathleen M. Sakamoto include:

  • Medicine (99 publications)
  • Biochemistry, Genetics and Molecular Biology (81 publications)

Their subfields of study focus largely on:

  • Molecular Biology (66 publications)
  • Hematology (36 publications)
  • Genetics (17 publications)
  • Public Health, Environmental and Occupational Health (14 publications)
  • Epidemiology (8 publications)

The primary research topics evident from their work encompass:

  • RNA modifications and cancer (40 publications)
  • Acute Myeloid Leukemia Research (38 publications)
  • Acute Lymphoblastic Leukemia research (26 publications)
  • Chronic Myeloid Leukemia Treatments (26 publications)
  • Cancer-related gene regulation (22 publications)
  • Chronic Lymphocytic Leukemia Research (14 publications)
  • Epigenetics and DNA Methylation (14 publications)

Best Publications

  • Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation.

    Kathleen M. Sakamoto;Kyung B. Kim;Akiko Kumagai;Frank Mercurio

  • The role of the transcription factor CREB in immune function.

    Andy Y. Wen;Kathleen M. Sakamoto;Lloyd S. Miller

  • The Role of HDAC6 in Cancer

    Grace I. Aldana-Masangkay;Kathleen M. Sakamoto

  • Chemical genetic control of protein levels: selective in vivo targeted degradation.

    John S. Schneekloth;Fabiana N. Fonseca;Michael Koldobskiy;Amit Mandal

  • Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia

    Charlotte M. Niemeyer;Michelle W. Kang;Danielle H. Shin;Ingrid Furlan

  • Development of Protacs to Target Cancer-promoting Proteins for Ubiquitination and Degradation

    Kathleen M. Sakamoto;Kathleen M. Sakamoto;Kyung B. Kim;Rati Verma;Andy Ransick

  • Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family.

    Nadia Danilova;Kathleen M. Sakamoto;Kathleen M. Sakamoto;Shuo Lin

  • CREB in the Pathophysiology of Cancer: Implications for Targeting Transcription Factors for Cancer Therapy

    Kathleen M. Sakamoto;David A. Frank

  • The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia

    Deepa B. Shankar;Jerry C. Cheng;Kentaro Kinjo;Noah Federman

  • Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation.

    Agustin Rodriguez-Gonzalez;Tara Lin;Alan K. Ikeda;Tiffany R Simms-Waldrip

  • Ubistatins Inhibit Proteasome-Dependent Degradation by Binding the Ubiquitin Chain

    Rati Verma;Noel R. Peters;Mariapina D'Onofrio;Gregory P. Tochtrop

  • BUBR1 deficiency results in abnormal megakaryopoiesis

    Qi Wang;Tongyi Liu;Yuqiang Fang;Suqing Xie

  • Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer.

    A Rodriguez-Gonzalez;K Cyrus;M Salcius;K Kim

  • Targeting CREB for cancer therapy: friend or foe.

    Xiangshu Xiao;Bingbing X Li;Bryan Mitton;Alan Ikeda

  • Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner.

    Malvyne Rolli;Alexey Kotlyarov;Kathleen M. Sakamoto;Matthias Gaestel

  • Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit.

    Wenying Shou;Kathleen M Sakamoto;Kathleen M Sakamoto;John Keener;Kenji W Morimoto

  • FMS-like tyrosine kinase 3 in normal hematopoiesis and acute myeloid leukemia.

    Bertrand W. Parcells;Alan K. Ikeda;Tiffany Simms-Waldrip;Theodore B. Moore

  • Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter.

    K. M. Sakamoto;J. K. Fraser;Hu-Jung J. Lee;E. Lehman

  • ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia

    Deepa B. Shankar;Junling Li;Paul Tapang;J. Owen McCall

  • RNA interference and human disease.

    Jerry C Cheng;Theodore B Moore;Kathleen M Sakamoto

Frequent Co-Authors

Shuo Lin
Shuo Lin University of California, Los Angeles
Raymond J. Deshaies
Raymond J. Deshaies California Institute of Technology
Craig M. Crews
Craig M. Crews Yale University
Stanley F. Nelson
Stanley F. Nelson University of California, Los Angeles
Manuel Serrano
Manuel Serrano Institució Catalana de Recerca i Estudis Avançats
Judith C. Gasson
Judith C. Gasson University of California, Los Angeles
Michael C. Bassik
Michael C. Bassik Stanford University
James E. Bradner
James E. Bradner Amgen (United States)
Hiromitsu Nakauchi
Hiromitsu Nakauchi Stanford University
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University

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