Scott Southwood

Overview

Best Publications

• The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

  A. Sette;A. Vitiello;B. Reherman;P. Fowler

  1098
  Citations

• Predicting population coverage of T-cell epitope-based diagnostics and vaccines

  Huynh-Hoa Bui;John Sidney;Kenny Dinh;Scott Southwood

  939
  Citations

• Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule.

  Jonathan A. Hill;Scott Southwood;Alessandro Sette;Anthony M. Jevnikar

  934
  Citations

• Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires

  Southwood S;Sidney J;Kondo A;del Guercio Mf

  832
  Citations

• Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.

  Maria R. Parkhurst;Michael L. Salgaller;Scott Southwood;Paul F. Robbins

  738
  Citations

• Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

  Y. Kawakami;S. Eliyahu;C. Jennings;K. Sakaguchi

  716
  Citations

• Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides

  Jeff Alexander;John Sidney;Scott Southwood;Jörg Ruppert

  654
  Citations

• Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo.

  C Pfeiffer;J Stein;S Southwood;H Ketelaar

  576
  Citations

• Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

  David A. Ostrov;Barry J. Grant;Yuri A. Pompeu;John Sidney

  481
  Citations

• Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1.

  Licia Rivoltini;Yutaka Kawakami;Kazuyasu Sakaguchi;Scott Southwood

  448
  Citations

• Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection.

  H M Diepolder;J T Gerlach;R Zachoval;R M Hoffmann

  424
  Citations

• Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.

  Kyong-Mi Chang;Barbara Rehermann;John G. McHutchison;Claudio Pasquinelli

  416
  Citations

• Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays

  A Sette;J Sidney;M F del Guercio;S Southwood

  396
  Citations

• The Multi-epitope Approach for Immunotherapy for Cancer: Identification of Several CTL Epitopes from Various Tumor-Associated Antigens Expressed on Solid Epithelial Tumors ☆

  Ichiro Kawashima;Stephen J Hudson;Van Tsai;Scott Southwood

  396
  Citations

• Melanoma-specific CD4 + T Cells Recognize Nonmutated HLA-DR-restricted Tyrosinase Epitopes

  Suzanne L. Topalian;Monica I. Gonzales;Maria Parkhurst;Yong F. Li

  393
  Citations

• Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

  K W Wucherpfennig;A Sette;S Southwood;C Oseroff

  384
  Citations

• On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.

  D O'Sullivan;T Arrhenius;J Sidney;M F Del Guercio

  357
  Citations

• Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules

  J Sidney;H M Grey;S Southwood;E Celis

  312
  Citations

• Specific binding of leukemia oncogene fusion protein peptides to HLA class I molecules.

  Monica Bocchia;Peggy A. Wentworth;Scott Southwood;John Sidney

  296
  Citations

• Identification of a Shared HLA-A*0201-restricted T-Cell Epitope from the Melanoma Antigen Tyrosinase-related Protein 2 (TRP2)

  Maria R. Parkhurst;Ellen B. Fitzgerald;Scott Southwood;Alessandro Sette

  296
  Citations

• Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells.

  Van Tsai;Scott Southwood;John Sidney;Kazuyasu Sakaguchi

  289
  Citations