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Sampsa Matikainen

Sampsa Matikainen

D-Index & Metrics

Microbiology

D-Index
73
Citations
18920
World Ranking
1665
National Ranking
19

Overview

Sampsa Matikainen is affiliated with the University of Helsinki in Finland. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, focusing on several subfields including Molecular Biology, Surgery, Immunology, Cancer Research, and Infectious Diseases.

The main topics of their research include:

  • Inflammasome and immune disorders
  • Lipoproteins and Cardiovascular Health
  • Extracellular vesicles in disease
  • Heme Oxygenase-1 and Carbon Monoxide
  • COVID-19 Clinical Research Studies
  • Kawasaki Disease and Coronary Complications
  • IL-33, ST2, and ILC Pathways

Frequent publication venues for Matikainen's work include:

  • The Journal of Immunology
  • Viruses
  • Cell Reports Medicine
  • Frontiers in Cardiovascular Medicine
  • Clinical & Translational Immunology

They have authored several recent papers such as:

  • "Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome," 2020, The Journal of Immunology
  • "Inflammasomes and SARS-CoV-2 Infection," 2021, Viruses
  • "Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis," 2024, Cell Reports Medicine
  • "Lipoprotein(a) induces caspase-1 activation and IL-1 signaling in human macrophages," 2023, Frontiers in Cardiovascular Medicine
  • "Native and oxidised lipoproteins negatively regulate the serum amyloid A-induced NLRP3 inflammasome activation in human macrophages," 2021, Clinical & Translational Immunology

Throughout their career, Matikainen has collaborated frequently with a number of researchers, including:

  • Tuula A. Nyman
  • Wojciech Cypryk
  • Katariina Nurmi
  • Kari K. Eklund
  • Martina B. Lorey

Best Publications

  • Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

    Kristiina Rajamäki;Jani Lappalainen;Katariina Öörni;Elina Välimäki

  • Distinct patterns and kinetics of chemokine production regulate dendritic cell function.

    Federica Sallusto;Belinda Palermo;Danielle Lenig;Minja Miettinen

  • IL-21 in Synergy with IL-15 or IL-18 Enhances IFN-γ Production in Human NK and T Cells

    Mari Strengell;Sampsa Matikainen;Jukka Sirén;Anne Lehtonen

  • Lactobacilli and Streptococci Induce Interleukin-12 (IL-12), IL-18, and Gamma Interferon Production in Human Peripheral Blood Mononuclear Cells

    Minja Miettinen;Sampsa Matikainen;Jaana Vuopio-Varkila;Jaana Pirhonen

  • Molecular pathogenesis of influenza A virus infection and virus-induced regulation of cytokine gene expression.

    Ilkka Julkunen;Timo Sareneva;Jaana Pirhonen;Tapani Ronni

  • Long, Needle-like Carbon Nanotubes and Asbestos Activate the NLRP3 Inflammasome through a Similar Mechanism

    Jaana Palomäki;Elina Välimäki;Jukka Sund;Minnamari Vippola

  • IL-33 and ST2 in Atopic Dermatitis: Expression Profiles and Modulation by Triggering Factors

    Terhi Savinko;Sampsa Matikainen;Ulpu Saarialho-Kere;Maili Lehto

  • Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells

    Sampsa Matikainen;Timo Sareneva;Tapani Ronni;Anne Lehtonen

  • IFNs activate toll-like receptor gene expression in viral infections.

    M Miettinen;T Sareneva;I Julkunen;S Matikainen

  • Virus infection activates IL-1 beta and IL-18 production in human macrophages by a caspase-1-dependent pathway.

    Jaana Pirhonen;Timo Sareneva;Masashi Kurimoto;Ilkka Julkunen

  • Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells.

    Timo Sareneva;Sampsa Matikainen;Masashi Kurimoto;Ilkka Julkunen

  • IL-21 Up-Regulates the Expression of Genes Associated with Innate Immunity and Th1 Response

    Mari Strengell;Timo Sareneva;Don Foster;Ilkka Julkunen

  • Inflammatory responses in influenza A virus infection.

    Ilkka Julkunen;Krister Melén;Maria Nyqvist;Jaana Pirhonen

  • Serum Amyloid A Activates the NLRP3 Inflammasome via P2X7 Receptor and a Cathepsin B-Sensitive Pathway

    Katri Niemi;Laura Teirilä;Jani Lappalainen;Kristiina Rajamäki

  • IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29

    Jukka Sirén;Jaana Pirhonen;Ilkka Julkunen;Sampsa Matikainen

  • (1,3)-β-Glucans Activate Both Dectin-1 and NLRP3 Inflammasome in Human Macrophages

    Päivi Kankkunen;Laura Teirilä;Johanna Rintahaka;Harri Alenius

  • Lactobacilli and Streptococci activate NF-kappa B and STAT signaling pathways in human macrophages.

    Minja Miettinen;Anne Lehtonen;Ilkka Julkunen;Sampsa Matikainen

  • Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages.

    A Lehtonen;S Matikainen;I Julkunen

  • Toll-like Receptor 3 Expressed by Melanoma Cells as a Target for Therapy?

    Bruno Salaun;Serge Lebecque;Sampsa Matikainen;Donata Rimoldi

  • Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells

    Pamela Österlund;Ville Veckman;Jukka Sirén;Kevin M. Klucher

Frequent Co-Authors

Ilkka Julkunen
Ilkka Julkunen University of Turku
Harri Alenius
Harri Alenius Karolinska Institute
Søren R. Paludan
Søren R. Paludan Aarhus University
Tero Aittokallio
Tero Aittokallio University of Helsinki
Mirja Salkinoja-Salonen
Mirja Salkinoja-Salonen University of Helsinki
Xavier Saelens
Xavier Saelens Ghent University
Tarja Porkka-Heiskanen
Tarja Porkka-Heiskanen University of Helsinki
Masashi Kurimoto
Masashi Kurimoto Okayama University
Jef K. De Brabander
Jef K. De Brabander The University of Texas Southwestern Medical Center
Petri T. Kovanen
Petri T. Kovanen Wihuri Research Institute

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