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Trine H. Mogensen

Trine H. Mogensen

D-Index & Metrics

Immunology

D-Index
51
Citations
16624
World Ranking
4108
National Ranking
41

Overview

Trine H. Mogensen is affiliated with Aarhus University in Denmark. Their research encompasses a broad range of topics primarily within the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. They have published extensively on Immunology, Infectious Diseases, Epidemiology, Molecular Biology, and Genetics.

Their work covers several main research topics, including:

  • Interferon and immune responses
  • Herpesvirus infections and treatments
  • COVID-19 clinical research studies
  • SARS-CoV-2 and COVID-19 research
  • Immunodeficiency and autoimmune disorders
  • Immune cell function and interaction
  • Cytomegalovirus and herpesvirus research

Mogensen's publication record includes studies in various scientific journals. Frequent venues for their work include:

  • The Journal of Experimental Medicine
  • Journal of Clinical Immunology
  • The Journal of Infectious Diseases
  • Frontiers in Immunology
  • Nature Communications

Among recent papers, notable contributions are:

  • "Autoantibodies against type I IFNs in patients with life-threatening COVID-19," 2020, Science
  • "SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate," 2020, Nature Communications
  • "Constitutive immune mechanisms: mediators of host defence and immune regulation," 2020, Nature Reviews Immunology
  • "A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection," 2020, Cell
  • "Studying severe long COVID to understand post-infectious disorders beyond COVID-19," 2022, Nature Medicine

The scientist frequently collaborates with several researchers, including:

  • Søren R. Paludan
  • Sofie E. Jørgensen
  • Jacques Fellay
  • Jean-Laurent Casanova
  • Paul Bastard

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

    Trine H. Mogensen

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

    Qian Zhang;Paul Bastard;Paul Bastard;Zhiyong Liu;Jérémie Le Pen

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • Molecular Pathways in Virus-Induced Cytokine Production

    Trine H. Mogensen;Søren R. Paludan

  • NF-κB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-κB-inducing kinase and IκB kinase

    Maryam Zamanian-Daryoush;Trine H. Mogensen;Joseph A. DiDonato;Bryan R. G. Williams

  • SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

    David Olagnier;Ensieh Farahani;Jacob Thyrsted;Julia Blay-Cadanet

  • Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS

    Line S Reinert;Katarína Lopušná;Katarína Lopušná;Henriette Winther;Chenglong Sun

  • IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

    Martin R. Jakobsen;Rasmus O. Bak;Annika Andersen;Randi K. Berg;Randi K. Berg

  • Constitutive immune mechanisms: mediators of host defence and immune regulation

    Søren R. Paludan;Søren R. Paludan;Thomas Pradeu;Seth L. Masters;Seth L. Masters;Trine H. Mogensen;Trine H. Mogensen

  • Long-term renal effects of a neutralizing RAGE antibody in obese type 2 diabetic mice

    Allan Flyvbjerg;Larry Denner;Bieke F. Schrijvers;Bieke F. Schrijvers;Ronald G. Tilton

  • Live Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis activate the inflammatory response through Toll-like receptors 2, 4, and 9 in species-specific patterns

    Trine H. Mogensen;Søren R. Paludan;Mogens Kilian;Lars Østergaard

  • IRF and STAT Transcription Factors - From Basic Biology to Roles in Infection, Protective Immunity, and Primary Immunodeficiencies.

    Trine H. Mogensen

  • HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression

    Maria H Christensen;Søren B Jensen;Juho J Miettinen;Stefanie Luecke

  • Innate immune recognition and activation during HIV infection

    Trine H Mogensen;Jesper Melchjorsen;Carsten S Larsen;Søren R Paludan

  • A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

    Jean-Laurent Casanova;Helen C. Su;Covid Human Genetic Effort

  • Functional IRF3 deficiency in a patient with herpes simplex encephalitis

    Line Lykke Andersen;Nanna Mørk;Line S. Reinert;Emil Kofod-Olsen

  • Reading the viral signature by Toll-like receptors and other pattern recognition receptors

    Trine H. Mogensen;Søren R. Paludan

  • TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

    Line Reinert;Louis Andreas Harder;Christian Holm;Marie Beck Iversen

  • Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

    Unknown

  • Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA

    Randi K. Berg;Jesper Melchjorsen;Johanna Rintahaka;Elisabeth Diget

  • p38 MAPK Autophosphorylation Drives Macrophage IL-12 Production during Intracellular Infection

    Leesun Kim;Laura Del Rio;Barbara A. Butcher;Trine H. Mogensen

  • Autoantibodies against type I IFNs in patients with critical influenza pneumonia

    Unknown

Frequent Co-Authors

Søren R. Paludan
Søren R. Paludan Aarhus University
Lars Østergaard
Lars Østergaard Aarhus University Hospital
Shen-Ying Zhang
Shen-Ying Zhang Rockefeller University
Rune Hartmann
Rune Hartmann Aarhus University
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Laurent Abel
Laurent Abel Université Paris Cité
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Darragh Duffy
Darragh Duffy Institut Pasteur
Aurélie Cobat
Aurélie Cobat Grenoble Alpes University

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