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Microbiology

D-Index
60
Citations
10457
World Ranking
3179
National Ranking
1258

Overview

Andrea Gambotto is affiliated with the University of Pittsburgh in the United States. Their research primarily focuses on medicine, with particular expertise in infectious diseases, immunology, pharmaceutical science, molecular biology, and oncology. The scientist's work addresses a range of topics including SARS-CoV-2 and COVID-19 research, immunotherapy and immune responses, COVID-19 clinical research studies, advancements in transdermal drug delivery, viral gastroenteritis research and epidemiology, virus-based gene therapy research, and animal virus infections studies.

Their recent scholarly output includes several peer-reviewed papers, notable among them:

  • Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development, 2020, EBioMedicine
  • A single subcutaneous or intranasal immunization with adenovirus-based SARS-CoV-2 vaccine induces robust humoral and cellular immune responses in mice, 2021, European Journal of Immunology
  • Improved Cutaneous Genetic Immunization by Microneedle Array Delivery of an Adjuvanted Adenovirus Vaccine, 2020, Journal of Investigative Dermatology
  • Impact of checkpoint blockade on cancer vaccine-activated CD8+ T cell responses, 2020, The Journal of Experimental Medicine
  • Haemophilus parasuis (Glaesserella parasuis) as a Potential Driver of Molecular Mimicry and Inflammation in Rheumatoid Arthritis, 2021, Frontiers in Medicine

Gambotto's collaborative work is reflected through frequent co-authorship with several researchers, including:

  • Shaohua Huang
  • Thomas W. Kenniston
  • Irene Cassaniti
  • Fausto Baldanti
  • Muhammad S. Khan

Their contributions have appeared in multiple scientific venues, with the most common publication outlets being:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Vaccines
  • Journal of Investigative Dermatology
  • EBioMedicine
  • European Journal of Immunology

Best Publications

  • Exosomes Derived from IL-10-Treated Dendritic Cells Can Suppress Inflammation and Collagen-Induced Arthritis

    Seon Hee Kim;Eric R. Lechman;Nicole Bianco;Rajasree Menon

  • Dendritic Cells Acquire Antigens from Live Cells for Cross-Presentation to CTL

    Larry A. Harshyne;Simon C. Watkins;Andrea Gambotto;Simon M. Barratt-Boyes

  • Human infection with highly pathogenic H5N1 influenza virus.

    Andrea Gambotto;Simon M Barratt-Boyes;Menno D de Jong;Menno D de Jong;Gabriele Neumann

  • Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development.

    Eun Kim;Geza Erdos;Shaohua Huang;Thomas W. Kenniston

  • Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization

    Wentao Gao;Adam C. Soloff;Xiuhua Lu;Angela Montecalvo

  • Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the adult populations of The Gambia, South Africa, and the United States.

    Edward Nwanegbo;Eftyhia Vardas;Wentao Gao;Hilton Whittle

  • Effects of a SARS-associated coronavirus vaccine in monkeys.

    Wentao Gao;Azaibi Tamin;Azaibi Tamin;Adam Soloff;Leonardo D'Aiuto

  • INTERLEUKIN-1F7B (IL-1H4/IL-1F7) IS PROCESSED BY CASPASE-1 AND MATURE IL-1F7B BINDS TO THE IL-18 RECEPTOR BUT DOES NOT INDUCE IFN-γ PRODUCTION

    Sanjay Kumar;Charles R. Hanning;Michael R. Brigham-Burke;David J. Rieman

  • Role of Toll-Like Receptors in Changes in Gene Expression and NF-κB Activation in Mouse Hepatocytes Stimulated with Lipopolysaccharide

    Shubing Liu;David J. Gallo;Angela M. Green;Debra L. Williams

  • Cisplatin-induced immune modulation in ovarian cancer mouse models with distinct inflammation profiles.

    Shannon Grabosch;Mirna Bulatovic;Feitianzhi Zeng;Feitianzhi Zeng;Tianzhou Ma;Tianzhou Ma

  • Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro.

    Nick Giannoukakis;William A. Rudert;Steve C. Ghivizzani;Andrea Gambotto

  • Identification of peptides that facilitate uptake and cytoplasmic and /or nuclear transport of proteins, DNA and viruses

    Paul D. Robbins;Zhibao Mi;Raymond Frizzell;Joseph C. Glorioso

  • Immunogenicity of enhanced green fluorescent protein (EGFP) in BALB/c mice: identification of an H2-Kd-restricted CTL epitope.

    A Gambotto;G Dworacki;V Cicinnati;T Kenniston

  • Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity

    Tomohide Tatsumi;Jian Huang;William E. Gooding;Andrea Gambotto

  • Potent antitumor effects mediated by local expression of the mature form of the interferon-γ inducing factor, interleukin-18 (IL-18)

    T Osaki;W Hashimoto;A Gambotto;H Okamura

  • Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees

    Eric R. Lechman;Daniel Jaffurs;Steven C. Ghivizzani;Andrea Gambotto

  • Immunogenicity of an adenoviral-based Middle East Respiratory Syndrome coronavirus vaccine in BALB/c mice

    Eun Kim;Kaori Okada;Tom Kenniston;V. Stalin Raj

  • A Role for Mitochondrial Bak in Apoptotic Response to Anticancer Drugs

    Gui Qiang Wang;Brian R. Gastman;Eva Wieckowski;Leslie A. Goldstein

  • IRF-1 expression induces apoptosis and inhibits tumor growth in mouse mammary cancer cells in vitro and in vivo.

    Peter K M Kim;Michaele Armstrong;Ye Liu;Peng Yan

  • Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I.

    N Giannoukakis;Z Mi;W A Rudert;A Gambotto

Frequent Co-Authors

Paul D. Robbins
Paul D. Robbins University of Minnesota
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Walter J. Storkus
Walter J. Storkus University of Pittsburgh
Michael T. Lotze
Michael T. Lotze University of Pittsburgh
Thomas Tüting
Thomas Tüting Otto-von-Guericke University Magdeburg
Louis D. Falo
Louis D. Falo University of Pittsburgh
Hideho Okada
Hideho Okada University of California, San Francisco
David A. Geller
David A. Geller University of Pittsburgh
Xiao Ming Yin
Xiao Ming Yin Indiana University
Noriko Murase
Noriko Murase University of Pittsburgh

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