World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
86
Citations
28483
World Ranking
1258
National Ranking
656

Medicine

D-Index
88
Citations
29710
World Ranking
13121
National Ranking
6694

Overview

Massimo Trucco is affiliated with Carnegie Mellon University in the United States. Their research spans several interconnected fields within medicine and molecular biology, focusing primarily on pancreatic function and diabetes, along with related areas such as pluripotent stem cells and oncology.

The main fields of study for Massimo Trucco include Medicine and Biochemistry, Genetics and Molecular Biology. Their subfields of focus are Surgery, Genetics, Molecular Biology, Endocrinology, Diabetes and Metabolism, and Oncology.

Their research topics cover a range of areas in diabetes and pancreatic health, including:

  • Pancreatic function and diabetes
  • Diabetes and associated disorders
  • Diabetes Management and Research
  • Pluripotent Stem Cells Research
  • Pancreatitis Pathology and Treatment
  • Xenotransplantation and immune response
  • Pancreatic and Hepatic Oncology Research

Recent publications by Massimo Trucco illustrate the scope and interdisciplinary nature of their work. Selected papers include:

  • "Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors," 2021, Translational Psychiatry
  • "De novo construction of T cell compartment in humanized mice engrafted with iPSC-derived thymus organoids," 2022, Nature Methods
  • "Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-trans Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation," 2021, Frontiers in Immunology
  • "Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice," 2021, Frontiers in Endocrinology
  • "Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist," 2022, Cardiovascular Diabetology

Frequent coauthors collaborating with Massimo Trucco include Rita Bottino, Nick Giannoukakis, Suzanne Bertera, Yésica Garciafigueroa, and Brett E. Phillips. These collaborations suggest a networked and multidisciplinary approach to their research work.

Their research has been published in a variety of academic venues, with recurring contributions to the International Journal of Radiation Oncology*Biology*Physics and UNC Libraries. Other venues include Translational Psychiatry, Nature Methods, and Frontiers in Immunology.

Best Publications

  • Production of α1,3-Galactosyltransferase-Deficient Pigs

    Carol J. Phelps;Chihiro Koike;Todd D. Vaught;Jeremy Boone

  • Cell migration, chimerism, and graft acceptance

    Thomas E. Starzl;Anthony J. Demetris;Noriko Murase;Suzanne Ildstad

  • Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance

    Thomas E. Starzl;Anthony J. Demetris;Massimo Trucco;Noriko Murase

  • Baboon-to-human liver transplantation

    T.E Starzl;J Fung;A Tzakis;S Todo

  • Tolerogenic immunosuppression for organ transplantation.

    Thomas E Starzl;Noriko Murase;Kareem Abu-Elmagd;Edward A Gray

  • Phase I (Safety) Study of Autologous Tolerogenic Dendritic Cells in Type 1 Diabetic Patients

    Nick Giannoukakis;Brett E. Phillips;David Finegold;Jo Harnaha

  • Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.

    Penelope A. Morel;Janice S. Dorman;John A. Todd;Hugh O. McDevitt

  • Chimerism and donor-specific nonreactivity 27 to 29 years after kidney allotransplantation.

    Thomas E. Starzl;Anthony J. Demetris;Massimo Trucco;Adriana Zeevi

  • Systemic chimerism in human female recipients of male livers.

    T.E Starzl;H Ramos;A Zeevi;C Ricordi

  • Clinical xenotransplantation: the next medical revolution?

    Burcin Ekser;Mohamed Ezzelarab;Hidetaka Hara;Dirk J. Van Der Windt;Dirk J. Van Der Windt;Dirk J. Van Der Windt

  • Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology

    Bernard Conrad;Eckhart Weidmann;Giuliana Trucco;William A. Rudert

  • Use of Differentiated Pluripotent Stem Cells in Replacement Therapy for Treating Disease

    Ira J. Fox;George Q. Daley;George Q. Daley;Steven A. Goldman;Steven A. Goldman;Johnny Huard

  • Response of human islets to isolation stress and the effect of antioxidant treatment.

    Rita Bottino;A.N. Balamurugan;Hubert Tse;C. Thirunavukkarasu

  • The lost chord: microchimerism and allograft survival

    Thomas E. Starzi;Anthony J. Demetris;Noriko Murase;Massimo Trucco

  • Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain.

    Janice S. Dorman;Ronald E. Laporte;Roslyn A. Stone;Massimo Trucco

  • Nitric Oxide Primes Pancreatic β Cells for Fas-mediated Destruction in Insulin-dependent Diabetes Mellitus

    Giorgio Stassi;Ruggero De Maria;Giuliana Trucco;William Rudert

  • CHIMERISM AFTER LIVER TRANSPLANTATION FOR TYPE IV GLYCOGEN STORAGE DISEASE AND TYPE 1 GAUCHER’S DISEASE

    Thomas E. Starzl;Anthony J. Demetris;Massimo Trucco;Camillo Ricordi

  • Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

    Thomas E. Starzl;Anthony J. Demetris;Noriko Murase;Angus W. Thomson

  • NKR-P1, a signal transduction molecule on natural killer cells

    Roberto Giorda;William A. Rudert;Carla Vavassori;William H. Chambers

  • Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation

    P Fontes;A.S Rao;P Carroll;F Dodson

  • Aspartic acid at position 57 of the DQ beta chain protects against type 1 diabetes: A family study

    P A Morel;J S Dorman;J A Todd;H O Mcdevitt

Frequent Co-Authors

Thomas E. Starzl
Thomas E. Starzl University of Pittsburgh
Anthony J. Demetris
Anthony J. Demetris University of Pittsburgh
Noriko Murase
Noriko Murase University of Pittsburgh
John J. Fung
John J. Fung University of Chicago
Paul D. Robbins
Paul D. Robbins University of Minnesota
Camillo Ricordi
Camillo Ricordi University of Miami
Roberto Giorda
Roberto Giorda MRC Laboratory of Molecular Biology
David K. C. Cooper
David K. C. Cooper University of Pittsburgh
Angus W. Thomson
Angus W. Thomson University of Pittsburgh
Dorothy J. Becker
Dorothy J. Becker University of Pittsburgh

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