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Neuroscience

D-Index
68
Citations
19380
World Ranking
2730
National Ranking
1276

Overview

Changiz Geula is affiliated with Northwestern University in the United States and has an extensive body of research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans subfields including Molecular Biology, Physiology, Neurology, Psychiatry and Mental Health, and Genetics.

The scientist's research focuses on multiple key topics:

  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA Research and Splicing
  • Amyotrophic Lateral Sclerosis Research
  • Neurobiology of Language and Bilingualism
  • Genetic Associations and Epidemiology

Among recent publications authored or co-authored by Changiz Geula are the following:

  • "Basal forebrain cholinergic system in the dementias: Vulnerability, resilience, and resistance," published in 2021 in the Journal of Neurochemistry
  • "Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway," 2021, Cell Reports
  • "Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds," 2021, Alzheimer s & Dementia
  • "Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma," 2023, Nature Immunology
  • "Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP type C," 2024, Nature

Frequent co-authors include:

  • Sandra Weintraub (41 collaborations)
  • Emily Rogalski (35 collaborations)
  • Tamar Gefen (34 collaborations)
  • Margaret E. Flanagan (30 collaborations)
  • Allegra Kawles (20 collaborations)

Changiz Geula's work is commonly published in the following venues:

  • Alzheimer s & Dementia (27 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (8 publications)
  • Neurology (4 publications)
  • Brain (3 publications)
  • Annals of Neurology (3 publications)

Best Publications

  • Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

    Joseph El Khoury;Michelle Toft;Suzanne E Hickman;Terry K Means

  • Neurobiology of butyrylcholinesterase.

    Sultan Darvesh;David A. Hopkins;Changiz Geula

  • Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

    Yevgenya Kraytsberg;Elena Kudryavtseva;Ann C McKee;Ann C McKee;Changiz Geula

  • Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity.

    Changiz Geula;Chuang Kuo Wu;Daniel Saroff;Alfredo Lorenzo

  • Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: Observations based on the distribution of acetylcholinesterase and choline acetyltransferase

    M‐Marsel ‐M Mesulam;Changiz Geula

  • Cytoarchitecture and neural afferents of orbitofrontal cortex in the brain of the monkey.

    R. J. Morecraft;C. Geula;M.-M. Mesulam

  • Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor

    Stephan Heckers;Toshiyuki Ohtake;Ronald G. Wiley;Douglas A. Lappi

  • Primary progressive aphasia and the evolving neurology of the language network

    M.-Marsel Mesulam;Emily J. Rogalski;Christina Wieneke;Robert S. Hurley

  • Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

    M.-Marsel Mesulam;Sandra Weintraub;Emily J. Rogalski;Christina Wieneke

  • Architecture of connectivity within a cingulo-fronto-parietal neurocognitive network for directed attention.

    Robert J. Morecraft;Changiz Geula;M.-Marsel Mesulam

  • Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia

    Marsel Mesulam;Changiz Geula

  • Human reticular formation: Cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons

    M. Marsel Mesulam;Changiz Geula;Mark A. Bothwell;Louis B. Hersh

  • The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

    Jin Xu;Nan Zhong;Haoyong Wang;Joshua E. Elias

  • Neuroglial cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability

    Christopher I. Wright;Changiz Geula;M.-Marsel Mesulam;M.-Marsel Mesulam

  • Cortical cholinergic fibers in aging and Alzheimer's disease: a morphometric study.

    C. Geula;M.-M. Mesulam

  • Systematic Regional Variations in the Loss of Cortical Cholinergic Fibers in Alzheimer's Disease

    Changiz Geula;M.-Marsel Mesulam

  • Cholinergic Neuronal and Axonal Abnormalities Are Present Early in Aging and in Alzheimer Disease

    Changiz Geula;Changiz Geula;Nicholas Nagykery;Alexander Nicholas;Chuang Kuo Wu

  • Cholinesterases and the pathology of Alzheimer disease.

    Changiz Geula;M.-Marsel Mesulam

  • Differential localization of nadph-diaphorase and calbindin-D28k within the cholinergic neurons of the basal forebrain, striatum and brainstem in the rat, monkey, baboon and human

    C. Geula;C.R. Schatz;M.-M. Mesulam

  • Anatomy of cholinesterase inhibition in Alzheimer's disease: effect of physostigmine and tetrahydroaminoacridine on plaques and tangles.

    M.‐Marsel Mesulam;Changiz Geula;M. Asuncion Morán

  • Differential cholinergic innervation within functional subdivisions of the human cerebral cortex: A choline acetyltransferase study

    M. ‐Marsel Mesulam;Louis B. Hersh;Deborah C. Mash;Changiz Geula

Frequent Co-Authors

M.-Marsel Mesulam
M.-Marsel Mesulam Northwestern University
Sandra Weintraub
Sandra Weintraub Northwestern University
Emily Rogalski
Emily Rogalski Northwestern University
Peter Heutink
Peter Heutink German Center for Neurodegenerative Diseases
Rosa Rademakers
Rosa Rademakers University of Antwerp
Glenda M. Halliday
Glenda M. Halliday University of Sydney
Stephan Heckers
Stephan Heckers Vanderbilt University Medical Center
Caroline Graff
Caroline Graff Karolinska University Hospital
Jeffery M. Vance
Jeffery M. Vance University of Miami
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami

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