2026 Haruki Okamura: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	78	1717	1564	63	58	285	33642

Overview

Haruki Okamura is affiliated with Hyogo College of Medicine in Japan and has contributed extensively to research in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields including Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, Reproductive Medicine, and Public Health, Environmental and Occupational Health.

Their research primarily focuses on immune cell function and interaction, inflammasome and immune disorders, ovarian function and disorders, IL-33, ST2, and ILC pathways, stress responses and cortisol, tryptophan and brain disorders, and diabetes and associated disorders.

Frequent coauthors in Okamura's publications include:

Kyosuke Yamanishi
Yoshimasa Tanaka
Antoaneta Gateva
Zdravko Kamenov
Tsvetelina Velikova

Okamura's research has been published in several scientific venues, notably:

Cells
Archives of Endocrinology and Metabolism
Cancer Immunology Immunotherapy
Translational Psychiatry
International Journal of Molecular Sciences

Their recent papers include:

IL-12 regulates the expansion, phenotype, and function of murine NK cells activated by IL-15 and IL-18 (2020) published in Cancer Immunology Immunotherapy
Elevated levels of interleukin-18 are associated with several indices of general and visceral adiposity and insulin resistance in women with polycystic ovary syndrome (2022) published in Archives of Endocrinology and Metabolism
Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice (2022) published in Translational Psychiatry
Molecular Mechanisms of IL18 in Disease (2023) published in International Journal of Molecular Sciences
Exploring Molecular Mechanisms Involved in the Development of the Depression-Like Phenotype in Interleukin-18-Deficient Mice (2021) published in BioMed Research International

Best Publications

Cloning of a new cytokine that induces IFN-gamma production by T cells.

H Okamura;H Tsutsi;T Komatsu;M Yutsudo

4030
Citations
Interleukin-18 regulates both Th1 and Th2 responses.

Kenji Nakanishi;Tomohiro Yoshimoto;Hiroko Tsutsui;Haruki Okamura

1864
Citations
Activation of Interferon-γ Inducing Factor Mediated by Interleukin-1β Converting Enzyme

Yong Gu;Keisuke Kuida;Hiroko Tsutsui;George Ku

1730
Citations
Defective NK Cell Activity and Th1 Response in IL-18–Deficient Mice

Kiyoshi Takeda;Hiroko Tsutsui;Tomohiro Yoshimoto;Osamu Adachi

1345
Citations
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production.

Tomohiro Yoshimoto;Kiyoshi Takeda;Takashi Tanaka;Kazunobu Ohkusu

1193
Citations
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein.

S Ushio;M Namba;T Okura;K Hattori

1001
Citations
Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu.

Kenji Nakanishi;Tomohiro Yoshimoto;Hiroko Tsutsui;Haruki Okamura

917
Citations
Regulation of interferon-gamma production by IL-12 and IL-18

Haruki Okamura;Shin-ichiro Kashiwamura;Hiroko Tsutsui;Tomohiro Yoshimoto

779
Citations
INTERLEUKIN-18: A NOVEL CYTOKINE THAT AUGMENTS BOTH INNATE AND ACQUIRED IMMUNITY

Haruki Okamura;Hiroko Tsutsui;Shin-Ichiro Kashiwamura;Tomohiro Yoshimoto

702
Citations
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

Tomohiro Yoshimoto;Hiroko Tsutsui;Kouji Tominaga;Katsuaki Hoshino

635
Citations
IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones.

H Tsutsui;K Nakanishi;K Matsui;K Higashino

633
Citations
Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation.

N Udagawa;N J Horwood;J Elliott;A Mackay

549
Citations
Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-γ production from activated B cells

Tomohiro Yoshimoto;Haruki Okamura;Yoh Ichi Tagawa;Yoichiro Iwakura

524
Citations
IL-18 induction of IgE: dependence on CD4+ T cells, IL-4 and STAT6.

Tomohiro Yoshimoto;Hitoshi Mizutani;Hiroko Tsutsui;Nancy Noben-Trauth

506
Citations
A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock.

H Okamura;K Nagata;T Komatsu;T Tanimoto

496
Citations
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Kazuyoshi Takeda

478
Citations
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.

H J Ahn;S Maruo;M Tomura;J Mu

458
Citations
IL-12 synergizes with IL-18 or IL-1β for IFN-γ production from human T cells

Kouji Tominaga;Tomohiro Yoshimoto;Kakuji Torigoe;Masashi Kurimoto

447
Citations
Endotoxin-induced serum factor that stimulates gamma interferon production.

K Nakamura;H Okamura;M Wada;K Nagata

410
Citations
Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells.

Shunji Sugawara;Akiko Uehara;Tomonori Nochi;Takahiro Yamaguchi

406
Citations

Frequent Co-Authors

Kenji Nakanishi Hyogo College of Medicine

Hiroko Tsutsui Hyogo College of Medicine

Masashi Kurimoto Okayama University

Yoshimasa Tanaka Nagasaki University

Tomohiro Yoshimoto Hyogo College of Medicine

Shizuo Akira Osaka University

Nagahiro Minato Kyoto University

Craig T. Morita University of Iowa

Tomohiro Matsuyama Hyogo College of Medicine

Shinji Takai Kitasato University

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