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Nagahiro Minato

Nagahiro Minato

D-Index & Metrics

Immunology

D-Index
78
Citations
32290
World Ranking
1718
National Ranking
64

Overview

Nagahiro Minato is affiliated with Kyoto University in Japan and focuses on immunology and molecular biology within biomedical research. Their work spans multiple interconnected fields with a primary emphasis on immune system function and related molecular mechanisms.

The main fields of study associated with their research include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields reflect a deep engagement with specific aspects of immune cell biology and oncology, including:

  • Immunology
  • Molecular Biology
  • Oncology
  • Neurology
  • Hematology

The scientist's research covers various topics related to immune functions and cellular dynamics, notably:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • Immunotherapy and Immune Responses
  • Single-cell and spatial transcriptomics
  • Telomeres, Telomerase, and Senescence
  • Barrier Structure and Function Studies

The list of recent papers documents their contributions to immunological science and cellular biology. Key publications include:

  • Physiology and pathology of T-cell aging, 2020, International Immunology
  • A circulating subset of iNKT cells mediates antitumor and antiviral immunity, 2022, Science Immunology
  • Selective expression of claudin-5 in thymic endothelial cells regulates the blood-thymus barrier and T-cell export, 2020, International Immunology
  • cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells, 2022, Cell Reports
  • SIPA1 enhances SMAD2/3 expression to maintain stem cell features in breast cancer cells, 2020, Stem Cell Research

The frequent co-authors collaborating with Nagahiro Minato include:

  • Masakazu Hattori
  • Yoko Hamazaki
  • Koichi Ikuta
  • Takeshi Ito
  • Kohei Kometani

Their work has been published repeatedly in venues dedicated to immunological and molecular research, including:

  • International Immunology
  • Science Immunology
  • Cell Reports
  • Stem Cell Research
  • International Journal of Biological Macromolecules

Best Publications

  • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.

    Hiroyuki Nishimura;Masato Nose;Hiroshi Hiai;Nagahiro Minato

  • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

    Yoshiko Iwai;Masayoshi Ishida;Yoshimasa Tanaka;Taku Okazaki

  • Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice

    Hiroyuki Nishimura;Taku Okazaki;Yoshimasa Tanaka;Kazuki Nakatani

  • Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.

    Junzo Hamanishi;Masaki Mandai;Masashi Iwasaki;Taku Okazaki

  • Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice

    Taku Okazaki;Yoshimasa Tanaka;Yoshimasa Tanaka;Ryosuke Nishio;Tamotsu Mitsuiye

  • Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

    Keisuke Kataoka;Yuichi Shiraishi;Yohei Takeda;Seiji Sakata

  • Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses.

    Hiroyuki Nishimura;Nagahiro Minato;Toru Nakano;Tasuku Honjo

  • The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors.

    David Yin-wei Lin;Yoshimasa Tanaka;Masashi Iwasaki;Apostolos G. Gittis

  • TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells).

    J Yodoi;K Teshigawara;T Nikaido;K Fukui

  • Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase.

    Koko Katagiri;Masakazu Hattori;Nagahiro Minato;Shin-kichi Irie

  • Developmentally regulated expression of the PD-1 protein on the surface of double-negative(CD4–CD8–) thymocytes

    Hiroyuki Nishimura;Yasutoshi Agata;Akemi Kawasaki;Masaki Sato

  • Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues.

    Masayoshi Ishida;Yoshiko Iwai;Yoshimasa Tanaka;Taku Okazaki

  • Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes.

    Kenji Kawada;Masahiro Sonoshita;Hiromi Sakashita;Arimichi Takabayashi

  • SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

    Takanori Kitamura;Kohei Kometani;Hiroki Hashida;Akihiro Matsunaga

  • The bHLH gene Hes1 is essential for expansion of early T cell precursors

    Koichi Tomita;Masakazu Hattori;Eijiro Nakamura;Shigetada Nakanishi

  • Cancer treating agent

    本庶 佑;Tasuku Honjo;佑 本庶;長博 湊

  • Obesity accelerates T cell senescence in murine visceral adipose tissue

    Kohsuke Shirakawa;Xiaoxiang Yan;Ken Shinmura;Jin Endo

  • Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study.

    Hirohito Kobayashi;Yoshimasa Tanaka;Junji Yagi;Yukinari Osaka

  • Analyses of peripheral blood mononuclear cells in operational tolerance after pediatric living donor liver transplantation.

    Ying Li;Takaaki Koshiba;Atsushi Yoshizawa;Yukihide Yonekawa

  • Facilitation of β Selection and Modification of Positive Selection in the Thymus of Pd-1–Deficient Mice

    Hiroyuki Nishimura;Tasuku Honjo;Nagahiro Minato

  • Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

    Yoko Hamazaki;Harumi Fujita;Takashi Kobayashi;Yongwon Choi

  • Mode of regulation of natural killer cell activity by interferon

    Nagahiro Minato;Lola Reid;Harvey Cantor;Peter Lengyel

Frequent Co-Authors

Yoshimasa Tanaka
Yoshimasa Tanaka Nagasaki University
Tasuku Honjo
Tasuku Honjo Kyoto University
Hiroshi Kawamoto
Hiroshi Kawamoto Kyoto University
Kazuhiro Iwai
Kazuhiro Iwai Kyoto University
Taku Okazaki
Taku Okazaki University of Tokushima
Hiroshi Hiai
Hiroshi Hiai Kyoto University
Haruki Okamura
Haruki Okamura Hyogo College of Medicine
Masakazu Toi
Masakazu Toi Kyoto University
Shimon Sakaguchi
Shimon Sakaguchi Osaka University

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