What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
His primary scientific interests are in Immunology, Peripheral tolerance, Cytotoxic T cell, Immune system and B7-H1 Antigen.
Taku Okazaki studied Immunology and Receptor that intersect with CD8 and Ovarian cancer.
His Peripheral tolerance study incorporates themes from Cell biology, IL-2 receptor and Antigen-presenting cell.
His Antigen-presenting cell research incorporates elements of Interferon gamma and Cytokine.
As a part of the same scientific study, Taku Okazaki usually deals with the Cytotoxic T cell, concentrating on Antibody and frequently concerns with Myocyte.
His work in B7-H1 Antigen addresses issues such as Cancer research, which are connected to fields such as Antigen, Cancer, Immunosuppression, Tumor-infiltrating lymphocytes and Pathology.
His most cited work include:
- Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. (3499 citations)
- PD-L2 is a second ligand for PD-1 and inhibits T cell activation (2108 citations)
- Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade (1942 citations)
What are the main themes of his work throughout his whole career to date?
Taku Okazaki focuses on Immunology, T cell, Molecular biology, Autoimmunity and Receptor.
His work in Autoimmune disease, CD28, Immune system, CD8 and Antigen are all subfields of Immunology research.
His biological study spans a wide range of topics, including Cell, Antibody and Inhibitory postsynaptic potential.
His Antigen research is multidisciplinary, incorporating elements of Autoantibody and Monoclonal antibody.
Taku Okazaki combines subjects such as Cytotoxic T cell, Co-receptor and Cell biology with his study of T cell.
The Receptor study combines topics in areas such as Peripheral tolerance and Immunohistochemistry.
He most often published in these fields:
- Immunology (50.54%)
- T cell (29.03%)
- Molecular biology (20.43%)
What were the highlights of his more recent work (between 2016-2020)?
- T cell (29.03%)
- Co-receptor (12.90%)
- Cell biology (22.58%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are T cell, Co-receptor, Cell biology, Immune system and Autoimmunity.
Taku Okazaki has included themes like Cancer research and Effector in his T cell study.
His research in Cancer research intersects with topics in Cell and Cytotoxic T cell.
His Cell biology research integrates issues from Immunotherapy, Stimulation, In vivo and T-cell receptor.
Taku Okazaki focuses mostly in the field of Immunotherapy, narrowing it down to topics relating to Cell culture and, in certain cases, Antigen.
The Autoimmunity study which covers Immune tolerance that intersects with Immunity.
Between 2016 and 2020, his most popular works were:
- Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses (105 citations)
- LAG-3 inhibits the activation of CD4 + T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII (59 citations)
- PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation. (41 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cytokine
Taku Okazaki spends much of his time researching Cell biology, T cell, Immunotherapy, Autoimmunity and Immune system.
His Cell biology research incorporates themes from Stimulation, Co-receptor, In vivo and T-cell receptor.
His research on T cell focuses in particular on CD28.
His Immunotherapy study combines topics from a wide range of disciplines, such as Plasma protein binding, Function, Receptor, Intracellular and Major histocompatibility complex.
His Autoimmunity study combines topics in areas such as Acquired immune system, Cancer, Cancer research, Clinical trial and Immune tolerance.
Taku Okazaki interconnects CD80 and Effector in the investigation of issues within Immune system.
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