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Chemistry

D-Index
68
Citations
16031
World Ranking
6548
National Ranking
224

Overview

Pierre Sinaÿ is affiliated with the École Normale Supérieure in France. Their research spans multiple fields, including Pharmacology, Toxicology and Pharmaceutics, Engineering, and Chemistry. This interdisciplinary approach supports a focus on both biomedical and chemical applications.

Their subfields of study include Pharmaceutical Science, Biomedical Engineering, and Spectroscopy. These subfields align with the broader domains of their work, integrating aspects of drug development, engineering techniques, and analytical methods.

The main topics addressed in their research include:

  • Drug Solubility and Delivery Systems
  • Microfluidic and Capillary Electrophoresis Applications
  • Analytical Chemistry and Chromatography

One recent publication is titled "Preparation of unsymmetrically 2A,3B,6C(F)-trihydroxy-per-O-methylated α-cyclodextrin and NMR analysis," published in 2020 in Tetrahedron Letters. This paper reflects their focus in chemical synthesis and analytical characterization using nuclear magnetic resonance techniques.

Frequent collaborators in their work include Sulong Xiao, Demin Zhou, Lihe Zhang, and Yongmin Zhang. These coauthors have contributed jointly on studies related to the topics and methods outlined above.

The primary venue for their publications is Tetrahedron Letters, where they have published work relevant to chemistry and related analytical sciences.

Best Publications

  • Structure-activity relationship in heparin : a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

    J. Choay;M. Petitou;J.C. Lormeau;P. Sinaÿ

  • Carbohydrates in chemistry and biology

    Beat Ernst;Gerald Warren Hart;Pierre Sinay

  • The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence. Chemical and 13C nuclear-magnetic-resonance studies.

    B Casu;P Oreste;G Torri;G Zoppetti

  • Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans

    B. Casu;M. Petitou;M. Provasoli;P. Sinaÿ

  • Structural studies on a biologically active hexasaccharide obtained from heparin.

    Jean Choay;Jean-Claude Lormeau;Maurice Petitou;Pierre Sinay

  • Total synthesis of a heparin pentasaccharide fragment having high affinity for antithrombin III

    Pierre Sinaÿ;Jean-Claude Jacquinet;Maurice Petitou;Philippe Duchaussoy

  • Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences.

    Dino R. Ferro;Augusto Provasoli;Massimo Ragazzi;Benito Casu

  • Evidence for conformational equilibrium of the sulfated L-iduronate residue in heparin and in synthetic heparin mono- and oligo-saccharides: NMR and force-field studies

    Dino R. Ferro;Augusto. Provasoli;Massimo. Ragazzi;Giangiacomo. Torri

  • Total synthesis and adjuvant activity of bacterial peptidoglycan derivatives.

    Claude Merser;Pierre Sinaÿ;Arlette Adam

  • Stereoselective synthesis of 2-thioglycosides of N-acetylneuraminic acid

    Alberto Marra;Pierre Sinaÿ

  • Expression of Heparan Sulfate d-Glucosaminyl 3-O-Sulfotransferase Isoforms Reveals Novel Substrate Specificities

    Jian Liu;Nicholas W. Shworak;Nicholas W. Shworak;Pierre Sinay;John J. Schwartz

  • RECENT ADVANCES IN GLYCOSYLATION REACTIONS

    P. Sinay

  • Triisobutylaluminium and diisobutylaluminium hydride as molecular scalpels: the regioselective stripping of perbenzylated sugars and cyclodextrins.

    Thomas Lecourt;Alexandre Herault;Alan J. Pearce;Matthieu Sollogoub

  • Synthesis of heparin fragments: A methyl α-pentaoside with high affinity for antithrombin III☆

    Maurice Petitou;Philippe Duchaussoy;Isidore Lederman;Jean Choay

  • A NOVEL SYNTHESIS OF 1,2-CIS-DISACCHARIDES

    J.‐R. Pougny;J.‐C. Jacquinet;M. Nassr;D. Duchet

  • Catching elusive glycosyl cations in a condensed phase with HF/SbF5 superacid

    A. Martin;A. Arda;J. Désiré;A. Martin-Mingot

  • Conformational analysis of nitrilium intermediates in glycosylation reactions

    I. Braccini;C. Derouet;J. Esnault;C.Herv′e de Penhoat

  • Diisobutylaluminum‐Promoted Regioselective De‐O‐benzylation of Perbenzylated Cyclodextrins: A Powerful New Strategy for the Preparation of Selectively Modified Cyclodextrins

    Alan J. Pearce;Pierre Sinaÿ

  • Preparation and reductive lithiation of 2-deoxy-D-glucopyranosyl phenylsulfones: A highly stereoselective route to C-glycosides☆

    Jean-Marie Beau;Pierre Sinaÿ

  • Mono- and bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: evidence for conformational peculiarity of the sulfated iduronate residue.

    G. Torri;B. Casu;G. Gatti;M. Petitou

Frequent Co-Authors

Maurice Petitou
Maurice Petitou University of Cambridge
Alberto Marra
Alberto Marra University of Montpellier
Jean Choay
Jean Choay Centre national de la recherche scientifique, CNRS
Jean-Marc Herbert
Jean-Marc Herbert Centre Hospitalier Universitaire de Tours
Pierre Vogel
Pierre Vogel École Polytechnique Fédérale de Lausanne
Giangiacomo Torri
Giangiacomo Torri Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni
Christian Amatore
Christian Amatore École Normale Supérieure
Benito Casu
Benito Casu Istituto G. Ronzoni
Gerald W. Hart
Gerald W. Hart University of Georgia

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