D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 63 Citations 13,534 302 World Ranking 5358 National Ranking 169

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Catalysis

Pierre Sinaÿ mainly focuses on Stereochemistry, Organic chemistry, Heparin, Biochemistry and Nuclear magnetic resonance spectroscopy. Pierre Sinaÿ works in the field of Stereochemistry, namely Glycoside. As a part of the same scientific family, Pierre Sinaÿ mostly works in the field of Organic chemistry, focusing on N-Acetylneuraminic acid and, on occasion, Chloride, Ethanethiol, Thiophenol and Thiocarbonate.

His Heparin research includes themes of Glycosaminoglycan, Tetrasaccharide, Biological activity, Chemical synthesis and Pharmacology. His Biochemistry research is multidisciplinary, incorporating perspectives in Biophysics and Phagocytosis. Pierre Sinaÿ combines subjects such as Alkylation, Electrophile, Medicinal chemistry, Lithium and C glycosides with his study of Nuclear magnetic resonance spectroscopy.

His most cited work include:

  • Structure-activity relationship in heparin : a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity (581 citations)
  • Carbohydrates in chemistry and biology (355 citations)
  • The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence. Chemical and 13C nuclear-magnetic-resonance studies. (280 citations)

What are the main themes of his work throughout his whole career to date?

Pierre Sinaÿ focuses on Stereochemistry, Organic chemistry, Disaccharide, Medicinal chemistry and Glycoside. Pierre Sinaÿ studies Stereochemistry, namely Anomer. In the subject of general Organic chemistry, his work in Glycosyl, Glycal and Yield is often linked to Triisobutylaluminium, thereby combining diverse domains of study.

Pierre Sinaÿ is studying Aldose, which is a component of Glycoside. The study incorporates disciplines such as Monosaccharide and Glycoside hydrolase in addition to Ring. The concepts of his Hydrogenolysis study are interwoven with issues in Bromide and Trifluoromethanesulfonate.

He most often published in these fields:

  • Stereochemistry (63.52%)
  • Organic chemistry (29.92%)
  • Disaccharide (13.39%)

What were the highlights of his more recent work (between 2003-2020)?

  • Stereochemistry (63.52%)
  • Organic chemistry (29.92%)
  • Cyclodextrin (6.82%)

In recent papers he was focusing on the following fields of study:

Stereochemistry, Organic chemistry, Cyclodextrin, Ring and Molecule are his primary areas of study. He specializes in Stereochemistry, namely Disaccharide. His study in the field of Reagent, Glycoside, Sugar and Carbohydrate chemistry is also linked to topics like Triisobutylaluminium.

His Cyclodextrin research is multidisciplinary, incorporating elements of Diol, Primary, Diisobutylaluminum hydride and Aqueous solution. His study looks at the relationship between Ring and fields such as Selective inhibition, as well as how they intersect with chemical problems. His studies deal with areas such as Computational chemistry, Nanotechnology, Polymer chemistry and Polymer as well as Molecule.

Between 2003 and 2020, his most popular works were:

  • Triisobutylaluminium and diisobutylaluminium hydride as molecular scalpels: the regioselective stripping of perbenzylated sugars and cyclodextrins. (126 citations)
  • The first synthesis of substituted azepanes mimicking monosaccharides: a new class of potent glycosidase inhibitors. (77 citations)
  • Catching elusive glycosyl cations in a condensed phase with HF/SbF5 superacid (71 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Catalysis

His primary areas of study are Stereochemistry, Ring, Glycoside hydrolase, Cyclodextrin and Organic chemistry. His Stereochemistry study incorporates themes from Lipid vesicle, Selectfluor, Mutase, Chemical synthesis and Monomer. His biological study spans a wide range of topics, including Imino Sugars, Molecule, Nucleophile and Hydroxymethyl.

His work deals with themes such as Acid catalyzed, Disaccharide, Isopropyl and Lone pair, which intersect with Glycoside hydrolase. His research in Cyclodextrin intersects with topics in Primary, Diisobutylaluminium hydride and Regioselectivity. Pierre Sinaÿ interconnects Yield, Selectivity and Tin in the investigation of issues within Primary.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure-activity relationship in heparin : a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

J. Choay;M. Petitou;J.C. Lormeau;P. Sinaÿ.
Biochemical and Biophysical Research Communications (1983)

879 Citations

Carbohydrates in chemistry and biology

Beat Ernst;Gerald Warren Hart;Pierre Sinay.
(2000)

568 Citations

The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence. Chemical and 13C nuclear-magnetic-resonance studies.

B Casu;P Oreste;G Torri;G Zoppetti.
Biochemical Journal (1981)

433 Citations

Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans

B. Casu;M. Petitou;M. Provasoli;P. Sinaÿ.
Trends in Biochemical Sciences (1988)

349 Citations

Structural studies on a biologically active hexasaccharide obtained from heparin.

Jean Choay;Jean-Claude Lormeau;Maurice Petitou;Pierre Sinay.
Annals of the New York Academy of Sciences (1981)

323 Citations

Total synthesis of a heparin pentasaccharide fragment having high affinity for antithrombin III

Pierre Sinaÿ;Jean-Claude Jacquinet;Maurice Petitou;Philippe Duchaussoy.
Carbohydrate Research (1984)

303 Citations

Total synthesis and adjuvant activity of bacterial peptidoglycan derivatives.

Claude Merser;Pierre Sinaÿ;Arlette Adam.
Biochemical and Biophysical Research Communications (1975)

276 Citations

Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences.

Dino R. Ferro;Augusto Provasoli;Massimo Ragazzi;Benito Casu.
Carbohydrate Research (1990)

275 Citations

Evidence for conformational equilibrium of the sulfated L-iduronate residue in heparin and in synthetic heparin mono- and oligo-saccharides: NMR and force-field studies

Dino R. Ferro;Augusto. Provasoli;Massimo. Ragazzi;Giangiacomo. Torri.
Journal of the American Chemical Society (1986)

265 Citations

Stereoselective synthesis of 2-thioglycosides of N-acetylneuraminic acid

Alberto Marra;Pierre Sinaÿ.
Carbohydrate Research (1989)

254 Citations

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