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Chemistry

D-Index
55
Citations
9986
World Ranking
12215
National Ranking
105

Overview

Mikael Bols is a researcher affiliated with the University of Copenhagen in Denmark. Their work spans multiple domains within chemistry and biochemistry, with a strong focus on molecular biology, organic chemistry, and pharmaceutical science.

Their primary fields of study include:

  • Chemistry
  • Biochemistry, Genetics and Molecular Biology

Within these fields, Mikael Bols has contributed to several subfields, such as:

  • Molecular Biology
  • Organic Chemistry
  • Pharmaceutical Science
  • Spectroscopy
  • Biomedical Engineering

The research topics covered in their publications feature:

  • Drug Solubility and Delivery Systems
  • Carbohydrate Chemistry and Synthesis
  • Analytical Chemistry and Chromatography
  • Glycosylation and Glycoproteins Research
  • Lysosomal Storage Disorders Research
  • Protein purification and stability
  • Phase Equilibria and Thermodynamics

Frequently collaborating with fellow researchers, Mikael Bols has worked alongside:

  • Martin Pedersen
  • Christian Pedersen
  • Julia Warren
  • Bo Wang
  • M. Zimmermann

Their research has been published in various scientific journals, with a notable presence in:

  • Organic & Biomolecular Chemistry
  • Beilstein Journal of Organic Chemistry
  • Carbohydrate Research
  • Angewandte Chemie International Edition
  • Chemistry - A European Journal

Key publications by Mikael Bols include:

  • Taming of the DIBAL Promoted Debenzylation of α-Cyclodextrin. Kinetics, Substituent Effects and Efficient Synthesis of Lings Tetrol, 2022, Chemistry - A European Journal
  • Imino- and Azasugar Protonation Inside Human Acid β-Glucosidase, the Enzyme that is Defective in Gaucher Disease (co-author), 2020, Angewandte Chemie International Edition
  • Imino- and Azasugar Protonation Inside Human Acid β-Glucosidase, the Enzyme that is Defective in Gaucher Disease (co-author), 2020, Angewandte Chemie
  • New methods of modification of α-cyclodextrin, 2024, Organic & Biomolecular Chemistry
  • CO2 complexation with cyclodextrins, 2023, Beilstein Journal of Organic Chemistry

Best Publications

  • Recent Developments of Transition-State Analogue Glycosidase Inhibitors of Non-Natural Product Origin

    Vinni H. Lillelund;Henrik H. Jensen;Xifu Liang;Mikael Bols

  • 1-AZA SUGARS, APPARENT TRANSITION STATE ANALOGUES OF EQUATORIAL GLYCOSIDE FORMATION/CLEAVAGE

    Mikael Bols

  • Silicon-Tethered Reactions

    Mikael. Bols;Troels. Skrydstrup

  • The disarming effect of the 4,6-acetal group on glycoside reactivity: torsional or electronic?

    Henrik Helligsø Jensen;Lars Ulrik Nordstrøm;Mikael Bols

  • Isofagomine, a Potent, New Glycosidase Inhibitor

    Tina M. Jespersen;Wenling Dong;Michael R. Sierks;Troels Skrydstrup

  • Stereoelectronic substituent effects.

    Henrik Helligsø Jensen;Mikael Bols

  • "Super armed" glycosyl donors: conformational arming of thioglycosides by silylation.

    Christian Marcus Pedersen;Lars Ulrik Nordstrøm;Mikael Bols

  • Mechanisms of Glycosylation Reactions Studied by Low-Temperature Nuclear Magnetic Resonance

    Tobias Gylling Frihed;Mikael Bols;Christian Marcus Pedersen

  • Garner's aldehyde

    Xifu Liang;Jens Andersch;Mikael Bols

  • Carbohydrate building blocks

    Mikael Bols

  • Artificial enzymes, “Chemzymes”: current state and perspectives

    Jeannette Bjerre;Cyril Rousseau;Lavinia Marinescu;Mikael Bols

  • Evaluation of Isofagomine and Its Derivatives As Potent Glycosidase Inhibitors

    Wenling Dong;Tina Jespersen;Mikael Bols;Troels Skrydstrup

  • Binding of serotonin to the human serotonin transporter. Molecular modeling and experimental validation.

    Leyla Celik;Steffen Sinning;Kasper Severinsen;Carsten G Hansen

  • Remarkable supramolecular catalysis of glycoside hydrolysis by a cyclodextrin cyanohydrin.

    Fernando Ortega-Caballero;Cyril Rousseau;Brian Christensen;Torben Ellebaek Petersen

  • Radical azidonation of aldehydes.

    Lavinia Marinescu;Jacob Thinggaard;Ib B Thomsen;Mikael Bols

  • Radical substitution with azide: TMSN3-PhI(OAc)2 as a substitute of IN3.

    Christian Marcus Pedersen;Lavinia Georgeta Marinescu;Mikael Bols

  • Stereoelectronic Substituent Effects in Polyhydroxylated Piperidines and Hexahydropyridazines

    Henrik Helligsø Jensen;Laila Lyngbye;Astrid Jensen;Mikael Bols

  • 1-Azafagomine: A Hydroxyhexahydropyridazine That Potently Inhibits Enzymatic Glycoside Cleavage

    Mikael Bols;Rita G. Hazell;Ib B. Thomsen

  • Very high rate enhancement of benzyl alcohol oxidation by an artificial enzyme.

    Lavinia G. Marinescu;Mikael Bols

  • Noeuromycin,1 A Glycosyl Cation Mimic that Strongly Inhibits Glycosidases

    Huizhen Liu;Xifu Liang;Helmer Søhoel;and Anne Bülow

  • Going to extremes: "super" armed glycosyl donors in glycosylation chemistry.

    Henrik H. Jensen;Christian Marcus Pedersen;Mikael Bols

Frequent Co-Authors

Troels Skrydstrup
Troels Skrydstrup Aarhus University
Feng-Ling Qing
Feng-Ling Qing Chinese Academy of Sciences
Carole C. Perry
Carole C. Perry Nottingham Trent University
Bent O. Petersen
Bent O. Petersen University of Copenhagen
Jens Ø. Duus
Jens Ø. Duus Technical University of Denmark
Morten Meldal
Morten Meldal University of Copenhagen
Birgit Schiøtt
Birgit Schiøtt Aarhus University
Torben E. Petersen
Torben E. Petersen Aarhus University
Birte Svensson
Birte Svensson Technical University of Denmark
Alexei V. Demchenko
Alexei V. Demchenko Saint Louis University

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