Jean Choay

Overview

Best Publications

• Structure-activity relationship in heparin : a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

  J. Choay;M. Petitou;J.C. Lormeau;P. Sinaÿ

  900
  Citations

• Role of the antithrombin-binding pentasaccharide in heparin acceleration of antithrombin-proteinase reactions. Resolution of the antithrombin conformational change contribution to heparin rate enhancement.

  S.T. Olson;I Björk;R Sheffer;P.A. Craig

  666
  Citations

• The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence. Chemical and 13C nuclear-magnetic-resonance studies.

  B Casu;P Oreste;G Torri;G Zoppetti

  443
  Citations

• Contribution of zinc and other metals to the biological activity of the serum thymic factor

  Mireille Dardenne;Jean-Marie Pleau;Bernadette Nabarra;Pierre Lefrancier

  411
  Citations

• Contribution of monosaccharide residues in heparin binding to antithrombin III.

  Donald H. Atha;Jean Claude Lormeau;Maurice Petitou;Robert D. Rosenberg

  343
  Citations

• Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs

  L Chedid;M Parant;F Parant;P Lefrancher

  339
  Citations

• Structural studies on a biologically active hexasaccharide obtained from heparin.

  Jean Choay;Jean-Claude Lormeau;Maurice Petitou;Pierre Sinay

  328
  Citations

• Total synthesis of a heparin pentasaccharide fragment having high affinity for antithrombin III

  Pierre Sinaÿ;Jean-Claude Jacquinet;Maurice Petitou;Philippe Duchaussoy

  312
  Citations

• Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences.

  Dino R. Ferro;Augusto Provasoli;Massimo Ragazzi;Benito Casu

  295
  Citations

• Evidence for conformational equilibrium of the sulfated L-iduronate residue in heparin and in synthetic heparin mono- and oligo-saccharides: NMR and force-field studies

  Dino R. Ferro;Augusto. Provasoli;Massimo. Ragazzi;Giangiacomo. Torri

  277
  Citations

• Modulation of the immune response by a synthetic adjuvant and analogs

  L Chedid;F Audibert;P Lefrancier;J Choay

  263
  Citations

• Structural Determinants of the Capacity of Heparin to Inhibit the Proliferation of Vascular Smooth Muscle Cells. II. Evidence for a Pentasaccharide Sequence That Contains a 3-O-Sulfate Group

  John J. Castellot;Jean Choay;Jean-Claude Lormeau;Maurice Petitou

  228
  Citations

• Synthesis of heparin fragments: A methyl α-pentaoside with high affinity for antithrombin III☆

  Maurice Petitou;Philippe Duchaussoy;Isidore Lederman;Jean Choay

  214
  Citations

• Inhibition of leucocyte elastase by heparin and its derivatives.

  F Redini;J M Tixier;M Petitou;J Choay

  197
  Citations

• Contribution of 3-O- and 6-O-sulfated glucosamine residues in the heparin-induced conformational change in antithrombin III.

  Donald H. Atha;Jean Claude Lormeau;Maurice Petitou;Robert D. Rosenberg

  187
  Citations

• Mono- and bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: evidence for conformational peculiarity of the sulfated iduronate residue.

  G. Torri;B. Casu;G. Gatti;M. Petitou

  156
  Citations

• Synthesis of heparin fragments. A chemical synthesis of the trisaccharide O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-α-d-glucopyranosyl)-(1→4)-O-(2-O-sulfo-α-l-idopyranosyluronic acid)-(1→4)-2-deoxy-2-sulfamido-6-O-sulfo-d-glucopyranose heptasodium salt

  Jean-Claude Jacquinet;Maurice Petitou;Philippe Duchaussoy;Isidore Lederman

  147
  Citations

• Crystal structure of cleaved bovine antithrombin III at 3·2 Å resolution

  Lionel Mourey;Jean-Pierre Samama;Marc Delarue;Maurice Petitou

  146
  Citations

• Conformation of the pentasaccharide corresponding to the binding site of heparin for antithrombin III.

  Massimo Ragazzi;Dino R. Ferro;Bruno Perly;Pierre Sinaÿ

  138
  Citations

• Synthesis of heparin fragments. A chemical synthesis of the pentasaccharide O-(2-deoxy-2-sulfamido-6-O-sulfo-α-D-glucopyranosyl)-(1→4)-O-(β-D-glucopyranosyluronic acid)-(1→4)-O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-α-D-gluco-pyranosyl)(1→4)-O-...

  M. Petitou;P. Duchaussoy;I. Lederman;J. Choay

  137
  Citations

• Antithrombotic activity of a synthetic heparin pentasaccharide in a rabbit stasis thrombosis model using different thrombogenic challenges.

  J.M. Walenga;M. Petitou;J.C. Lormeau;M. Samama

  128
  Citations

• Synthesis of heparin fragments. A chemical synthesis of the pentasaccharide O-(2-deoxy-2-sulfamido-6-O-sulfo-α-?-glucopyranosyl)-(1→4)-O-(β-?-glucopyranosyluronic acid)-(1→4)-O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-α-?-glucopyranosyl)-(1→4)-O-(2-O-sulfo-α-?-idopyranosyluronic acid)-(1→4)-2-deoxy-2-sul

  Unknown

  19
  Citations