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D-Index
72
Citations
18499
World Ranking
19842
National Ranking
1783

Overview

Michael Laffan is affiliated with Imperial College London in the United Kingdom. Their research activity is primarily situated within the field of Medicine, with a significant focus on Hematology. Other subfields include Internal Medicine, Surgery, Infectious Diseases, and Genetics.

Their research covers a variety of specialized topics centered on blood disorders and related clinical conditions. Key areas of work are:

  • Platelet Disorders and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • COVID-19 Clinical Research Studies
  • Hemophilia Treatment and Research
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Blood Coagulation and Thrombosis Mechanisms
  • COVID-19 and healthcare impacts

Michael Laffan has contributed to multiple publications in journals that frequently feature their research. Notable venues include:

  • British Journal of Haematology
  • Journal of Thrombosis and Haemostasis
  • Research and Practice in Thrombosis and Haemostasis
  • Blood
  • Haemophilia

Frequent collaborators in their research encompass:

  • Deepa J. Arachchillage
  • Indika Rajakaruna
  • Nicola Curry
  • Richard Szydlo
  • Zain Odho

Among recent papers associated with Michael Laffan are:

  • Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19, 2021, New England Journal of Medicine
  • Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia, 2020, Journal of Thrombosis and Haemostasis
  • Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A, 2020, New England Journal of Medicine
  • ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease, 2021, Blood Advances
  • COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects, 2021, Angiogenesis

Best Publications

  • Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

    Simone Wahl;Alexander Drong;Benjamin Lehne;Marie Loh;Marie Loh;Marie Loh

  • AAV5–Factor VIII Gene Transfer in Severe Hemophilia A

    Savita Rangarajan;Liron Walsh;Will Lester;David Perry

  • Endothelial von Willebrand factor regulates angiogenesis

    Richard D. Starke;Francesco Ferraro;Koralia E. Paschalaki;Nicola H. Dryden

  • Whole-genome sequencing of patients with rare diseases in a national health system.

    E Turro;W J Astle;W J Astle;K Megy;S Gräf

  • Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A

    K John Pasi;Savita Rangarajan;Nina Mitchell;Will Lester

  • The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology

    Mike A. Laffan;Will Lester;James S. O'Donnell;Andrew Will

  • Whole-genome sequencing of patients with rare diseases in a national health system

    Ernest Turro;William J Astle;Karyn Megy;Stefan Graf

  • The relationship between ABO histo-blood group, factor VIII and von Willebrand factor.

    J. O'Donnell;M. A. Laffan

  • Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia.

    Deepa R. J. Arachchillage;Deepa R. J. Arachchillage;Mike Laffan;Mike Laffan

  • Transcriptional diversity during lineage commitment of human blood progenitors

    Lu Chen;Lu Chen;Lu Chen;Myrto Kostadima;Myrto Kostadima;Myrto Kostadima;Joost H. A. Martens;Giovanni Canu;Giovanni Canu

  • High prevalence of elevated factor VIII levels in patients referred for thrombophilia screening: role of increased synthesis and relationship to the acute phase reaction.

    J O’Donnell;E G D Tuddenham;R Manning;G Kemball-Cook

  • Randomised trials of human albumin for adults with sepsis: systematic review and meta-analysis with trial sequential analysis of all-cause mortality

    Amit Patel;Amit Patel;Michael A Laffan;Umeer Waheed;Stephen J Brett

  • Elevation of FVIII : C in Venous Thromboembolism Is Persistent and Independent of the Acute Phase Response

    James O'Donnell;Andrew D. Mumford;Richard A. Manning;Michael Laffan

  • Guideline on the management of bleeding in patients on antithrombotic agents.

    Mike Makris;Joost J Van Veen;Campbell R Tait;Andrew D Mumford

  • Bleeding symptoms and coagulation abnormalities in 337 patients with AL-amyloidosis

    Andrew D. Mumford;James O'donnell;Julian D. Gillmore;Richard A. Manning

  • The Use of Fresh-Frozen Plasma in England: High Levels of Inappropriate Use in Adults and Children

    Simon J. Stanworth;John Grant-Casey;Derek Lowe;Mike Laffan

  • The diagnosis of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization.

    M. Laffan;S. A. Brown;Peter William Collins;A. M. Cumming

  • Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial.

    P Chowdary;S Lethagen;S Lethagen;U Friedrich;B Brand

  • Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarction.

    E. Mercuri;F. Cowan;G. Gupte;R. Manning

  • ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease.

    Nathan T. Connell;Veronica H. Flood;Romina Brignardello-Petersen;Rezan Abdul-Kadir

Frequent Co-Authors

Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Jonathan Stephens
Jonathan Stephens University of Cambridge
David Lane
David Lane Imperial College London
Timothy J. Aitman
Timothy J. Aitman University of Edinburgh
Peter Collins
Peter Collins Cardiff University
Simon J. Stanworth
Simon J. Stanworth NHS Blood and Transplant
Dorian O. Haskard
Dorian O. Haskard Imperial College London
Rémi Favier
Rémi Favier University of Paris-Saclay
Daniel F. Cutler
Daniel F. Cutler University College London

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