World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
48
Citations
39983
World Ranking
15035
National Ranking
226

Research.com Recognitions

  • 2003 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences for his development of refinement techniques for macromolecules". Jones: "for his pioneering development of methods to interpret electron density maps and to build models of biological macromolecules with the aid of computer graphics

Overview

T.A. Jones is affiliated with Uppsala University in Sweden and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, as well as medicine. Their research spans multiple subfields including molecular biology, genetics, immunology, molecular medicine, and infectious diseases.

The scientist's recent publications cover diverse topics, with a focus on glioma diagnosis and treatment, immune cells in cancer, antibiotic resistance in bacteria, tuberculosis research and epidemiology, RNA research and splicing, RNA modifications and cancer, and RNA regulation and disease.

Recent papers authored or coauthored by Jones include:

  • "Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates" (2020, EMBO Reports)
  • "Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma" (2021, Nature Communications)
  • "Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria" (2024, Proceedings of the National Academy of Sciences)
  • "Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors" (2024, European Journal of Medicinal Chemistry)
  • "A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas" (2025, Nature Communications)

Jones frequently publishes in several scientific journals, notably:

  • Nature Communications
  • Neuro-Oncology
  • EMBO Reports
  • Proceedings of the National Academy of Sciences
  • European Journal of Medicinal Chemistry

Collaborations have been a notable part of Jones's career. Frequent coauthors include Denise Sheer, Lewis Woodward, David Jones, Sha Cao, and Edouard Zamaratski, reflecting active interdisciplinary teamwork and contributions to various aspects of biomedical research.

Among awards, Jones received the Gregori Aminoff Prize from the Royal Swedish Academy of Sciences in 2003, cited for the development of refinement techniques for macromolecules and pioneering methods to interpret electron density maps and create models of biological macromolecules using computer graphics.

Best Publications

  • Improved methods for building protein models in electron density maps and the location of errors in these models.

    T.A. Jones;J.-Y. Zou;S.W. Cowan;M. Kjeldgaard

  • A graphics model building and refinement system for macromolecules

    T. A. Jones

  • Detection, delineation, measurement and display of cavities in macromolecular structures

    G. J. Kleywegt;T. A. Jones

  • The structure of β -lactoglobulin and its similarity to plasma retinol-binding protein

    M. Z. Papiz;L. Sawyer;E. E. Eliopoulos;A. C. T. North

  • Using known substructures in protein model building and crystallography

    T A Jones;S Thirup

  • Electron-density map interpretation.

    T.A. Jones;M. Kjeldgaard

  • Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecificity pocket for secondary alcohols.

    J Uppenberg;N Ohrner;M Norin;K Hult

  • Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei. A study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing.

    J Kraulis;G.M Clore;M Nilges;T.A Jones

  • Databases in Protein Crystallography

    G.J. Kleywegt;T.A. Jones

  • High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei.

    Christina Divne;J Stahlberg;T T Teeri;T A Jones

  • Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.

    I. Sinning;G. J. Kleywegt;S. W. Cowan;P. Reinemer

  • The three-dimensional structure of retinol-binding protein.

    M.E. Newcomer;T.A. Jones;J. Aqvist;J. Sundelin

  • Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG

    A.E. Sauer-Eriksson;G.J. Kleywegt;M. Uhlen;T.A. Jones

  • Structure of a triclinic ternary complex of horse liver alcohol dehydrogenase at 2.9 A resolution.

    H Eklund;J.P Samma;L Wallen;C.I Branden

  • Detecting folding motifs and similarities in protein structures.

    GJ Kleywegt;TA Jones

  • Model building and refinement practice.

    GJ Kleywegt;TA Jones

  • xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets.

    G. J. Kleywegt;T. A. Jones

  • The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study

    Holak Ta;Engström A;Kraulis Pj;Lindeberg G

  • The crystal structure of the catalytic core domain of endoglucanase I from Trichoderma reesei at 3.6 A resolution, and a comparison with related enzymes.

    G J Kleywegt;J Y Zou;Christina Divne;G J Davies

  • Trichoderma reesei cellobiohydrolases: why so efficient on crystalline cellulose?

    T T Teeri;A Koivula;M Linder;G Wohlfahrt

Frequent Co-Authors

Gerard J. Kleywegt
Gerard J. Kleywegt European Bioinformatics Institute
Alexander D. Cameron
Alexander D. Cameron University of Warwick
Sherry L. Mowbray
Sherry L. Mowbray Uppsala University
Jerry Ståhlberg
Jerry Ståhlberg Swedish University of Agricultural Sciences
Bengt Mannervik
Bengt Mannervik Stockholm University
Tuula T. Teeri
Tuula T. Teeri Royal Swedish Academy of Engineering Sciences
Johan Åqvist
Johan Åqvist Uppsala University
Franz Oesch
Franz Oesch Johannes Gutenberg University of Mainz
David I. Stuart
David I. Stuart University of Oxford
Michael Arand
Michael Arand University of Zurich

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