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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
18828
World Ranking
13562
National Ranking
5749

Overview

Brian D. Brown is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans several intersecting domains within the biomedical sciences, notably immunology, oncology, and molecular biology.

The main fields of study associated with their work include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of focus highlight specialization within these areas:

  • Immunology
  • Oncology
  • Molecular Biology
  • Infectious Diseases
  • Cancer Research

Their research topics reflect an emphasis on immune system function and related therapeutic strategies:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • T-cell and B-cell Immunology
  • Immune cells in cancer
  • Phagocytosis and Immune Regulation

Brian D. Brown has several frequent collaborators, including Miriam Mérad, Thomas U. Marron, Matthew D. Park, Nina Bhardwaj, and Jessica Le Bérichel.

Their work is published regularly in a range of scientific venues. The most common publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Nature
  • Regular and Young Investigator Award Abstracts
  • Immunity

Recent papers authored or co-authored by Brian D. Brown include:

  • "Immunology of COVID-19: Current State of the Science" (2020), published in Immunity
  • "A conserved dendritic-cell regulatory program limits antitumour immunity" (2020), published in Nature
  • "Cancer vaccines: the next immunotherapy frontier" (2022), published in Nature Cancer
  • "Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells" (2021), published in Nature
  • "The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments" (2021), published in Nature Communications

Best Publications

  • Immunology of COVID-19: Current State of the Science.

    Nicolas Vabret;Graham J. Britton;Conor Gruber;Samarth Hegde

  • Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

    Hélène Salmon;Juliana Idoyaga;Adeeb Rahman;Marylène Leboeuf

  • A conserved dendritic-cell regulatory program limits antitumour immunity

    Barbara Maier;Andrew M. Leader;Steven T. Chen;Navpreet Tung

  • Deciphering the transcriptional network of the dendritic cell lineage

    Jennifer C Miller;Brian D Brown;Tal Shay;Emmanuel L Gautier;Emmanuel L Gautier

  • Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state

    Brian D Brown;Bernhard Gentner;Alessio Cantore;Silvia Colleoni

  • β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma

    Marina Ruiz de Galarreta;Erin Bresnahan;Pedro Molina-Sánchez;Katherine E. Lindblad

  • Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer

    Brian D Brown;Mary Anna Venneri;Anna Zingale;Lucia Sergi Sergi

  • Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

    Brian D. Brown;Luigi Naldini

  • Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.

    María Casanova-Acebes;Erica Dalla;Andrew M. Leader;Jessica LeBerichel

  • The cis-Regulatory Atlas of the Mouse Immune System

    Hideyuki Yoshida;Caleb A. Lareau;Ricardo N. Ramirez;Samuel A. Rose

  • GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

    Melanie Greter;Julie Helft;Andrew Chow;Daigo Hashimoto

  • High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

    Gavriel Mullokandov;Alessia Baccarini;Albert Ruzo;Anitha D Jayaprakash

  • Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination.

    Linda Hammerich;Thomas U. Marron;Ranjan Upadhyay;Judit Svensson-Arvelund

  • Stable knockdown of microRNA in vivo by lentiviral vectors.

    Bernhard Gentner;Giulia Schira;Alice Giustacchini;Mario Amendola

  • TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

    Priyanka Nair-Gupta;Alessia Baccarini;Navpreet Tung;Fabian Seyffer

  • Studying the mononuclear phagocyte system in the molecular age

    Andrew Chow;Brian D. Brown;Miriam Merad

  • A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

    Brian D. Brown;Alessio Cantore;Andrea Annoni;Lucia Sergi Sergi

  • Identification and remediation of biases in the activity of RNA ligases in small-RNA deep sequencing

    Anitha D. Jayaprakash;Omar Jabado;Brian D. Brown;Ravi Sachidanandam

  • Kinetic Analysis Reveals the Fate of a MicroRNA following Target Regulation in Mammalian Cells

    Alessia Baccarini;Hemangini Chauhan;Thomas J. Gardner;Anitha D. Jayaprakash

  • microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

    Aditya Parikh;Christine Lee;Peronne Joseph;Sergio Marchini

Frequent Co-Authors

Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
David Lillicrap
David Lillicrap Queen's University
Luigi Naldini
Luigi Naldini Vita-Salute San Raffaele University
Nina Bhardwaj
Nina Bhardwaj Icahn School of Medicine at Mount Sinai
Gwendalyn J. Randolph
Gwendalyn J. Randolph Washington University in St. Louis
Amy J. Wagers
Amy J. Wagers Harvard University
Ravi Sachidanandam
Ravi Sachidanandam Icahn School of Medicine at Mount Sinai
Sacha Gnjatic
Sacha Gnjatic Icahn School of Medicine at Mount Sinai
Christophe Benoist
Christophe Benoist Harvard University

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