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Genetics

D-Index
76
Citations
36317
World Ranking
1794
National Ranking
822

Overview

Ravi Sachidanandam is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans multiple domains within medicine and molecular biology, including immunology, infectious diseases, and oncology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Within these broader fields, their work focuses especially on the following subfields:

  • Immunology
  • Molecular Biology
  • Infectious Diseases
  • Epidemiology
  • Oncology

Ravi Sachidanandam's research explores several key scientific topics, including:

  • Immune Cell Function and Interaction
  • RNA modifications and cancer
  • Viral Infections and Outbreaks Research
  • Hepatitis B Virus Studies
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • RNA Research and Splicing

The scientist has published extensively in reputable journals, frequently contributing to:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • Viruses
  • Thyroid

Among recent papers are:

  • High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer, 2021, Nature Communications
  • ISG15 deficiency restricts HIV-1 infection, 2022, PLoS Pathogens
  • Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex, 2021, Nature Communications
  • Marburg and Ebola Virus Infections Elicit a Complex, Muted Inflammatory State in Bats, 2023, Viruses
  • The Transient Human Thyroid Progenitor Cell: Examining the Thyroid Continuum from Stem Cell to Follicular Cell, 2021, Thyroid

The scientist collaborates with several frequent co-authors, including:

  • Anitha D. Jayaprakash
  • Saboor Hekmaty
  • Adam J. Ronk
  • Abhishek N. Prasad
  • Michael F. Covington

Best Publications

  • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

    Ravi Sachidanandam;David Weissman;Steven C. Schmidt;Jerzy M. Kakol

  • Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila

    Julius Brennecke;Alexei A. Aravin;Alexander Stark;Monica Dus

  • A germline-specific class of small RNAs binds mammalian Piwi proteins

    Angélique Girard;Angélique Girard;Ravi Sachidanandam;Gregory J. Hannon;Michelle A. Carmell

  • A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.

    Alexei A. Aravin;Alexei A. Aravin;Ravi Sachidanandam;Ravi Sachidanandam;Deborah Bourc'his;Christopher Schaefer;Christopher Schaefer

  • Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

    Oliver H. Tam;Alexei A. Aravin;Paula Stein;Angelique Girard

  • Developmentally Regulated piRNA Clusters Implicate MILI in Transposon Control

    Alexei A. Aravin;Ravi Sachidanandam;Angelique Girard;Katalin Fejes-Toth

  • De novo mutations in histone-modifying genes in congenital heart disease

    Samir Zaidi;Murim Choi;Hiroko Wakimoto;Lijiang Ma

  • Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary

    Colin D. Malone;Colin D. Malone;Julius Brennecke;Julius Brennecke;Monica Dus;Monica Dus;Alexander Stark

  • A resource for large-scale RNA-interference-based screens in mammals

    Patrick J. Paddison;Jose M. Silva;Douglas S. Conklin;Douglas S. Conklin;Mike Schlabach;Mike Schlabach

  • An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

    Julius Brennecke;Colin D. Malone;Alexei A. Aravin;Ravi Sachidanandam

  • An endogenous small interfering RNA pathway in Drosophila

    Benjamin Czech;Colin D. Malone;Rui Zhou;Alexander Stark;Alexander Stark

  • Second-generation shRNA libraries covering the mouse and human genomes.

    Jose M Silva;Mamie Z Li;Ken Chang;Wei Ge

  • Genome analysis of the platypus reveals unique signatures of evolution

    Wesley C. Warren;La Deana W. Hillier;Jennifer A. Marshall Graves;Ewan Birney

  • From silencing to gene expression: real-time analysis in single cells.

    Susan M Janicki;Toshiro Tsukamoto;Simone E Salghetti;William P Tansey

  • Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells

    Mariia Yuneva;Nicola Zamboni;Peter Oefner;Ravi Sachidanandam

  • Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution

    Jeramiah J. Smith;Shigehiro Kuraku;Carson Holt;Tatjana Sauka-Spengler

  • Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs.

    Katalin Fejes-Toth;Vihra Sotirova;Ravi Sachidanandam;Gordon Assaf

  • Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

    Alina Baum;Ravi Sachidanandam;Adolfo García-Sastre

  • Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

    Michael Reuter;Philipp Berninger;Shinichiro Chuma;Hardik Shah

  • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer (Nature (2007) 449, (682-688))

    Li Ma;Julie Teruya-Feldstein;Robert A. Weinberg

Frequent Co-Authors

Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Alexei A. Aravin
Alexei A. Aravin California Institute of Technology
Alexander Stark
Alexander Stark Research Institute of Molecular Pathology
Julius Brennecke
Julius Brennecke Austrian Academy of Sciences
Stuart A. Aaronson
Stuart A. Aaronson Icahn School of Medicine at Mount Sinai
Brian D. Brown
Brian D. Brown Icahn School of Medicine at Mount Sinai
Christopher F. Basler
Christopher F. Basler University of Georgia
Vessela N. Kristensen
Vessela N. Kristensen Oslo University Hospital
Adrian R. Krainer
Adrian R. Krainer Cold Spring Harbor Laboratory

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