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Genetics

D-Index
43
Citations
23996
World Ranking
4270
National Ranking
20

Overview

Julius Brennecke is affiliated with the Austrian Academy of Sciences in Austria, where their research primarily focuses on biochemistry, genetics, and molecular biology. Their work encompasses several specialized subfields including molecular biology, plant science, biomedical engineering, infectious diseases, and genetics.

The scientist's research explores various topics related to chromosomal and genetic variations, CRISPR and genetic engineering, advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, genomics and chromatin dynamics, RNA modifications and cancer, and RNA research and splicing.

Julius Brennecke has published extensively, with significant contributions appearing in a range of scientific journals. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), where they published 18 papers, eLife with 4 publications, Nature with 2 publications, as well as Nucleic Acids Research and Frontiers in Molecular Biosciences.

Notable recent papers by Brennecke and collaborators include:

  • Structure of the human core transcription-export complex reveals a hub for multivalent interactions, 2020, eLife
  • The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters, 2022, eLife
  • A universal method for the rapid isolation of all known classes of functional silencing small RNAs, 2020, Nucleic Acids Research
  • A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing, 2022, Frontiers in Molecular Biosciences
  • Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq, 2021, Nature Communications

The scientist frequently collaborates with several researchers, with the most frequent co-authors being:

  • Dominik Handler (22 co-authored publications)
  • Peter Duchek (13 co-authored publications)
  • Ulrich Hohmann (10 co-authored publications)
  • László Tirián (10 co-authored publications)
  • Kirsten-André Senti (8 co-authored publications)

Best Publications

  • Principles of MicroRNA–Target Recognition

    Julius Brennecke;Alexander Stark;Robert B Russell;Stephen M Cohen

  • Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila

    Julius Brennecke;Alexei A. Aravin;Alexander Stark;Monica Dus

  • bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

    Julius Brennecke;David R. Hipfner;Alexander Stark;Robert B. Russell

  • Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution.

    Alexander Stark;Julius Brennecke;Natascha Bushati;Robert B. Russell

  • The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race

    Alexei A. Aravin;Gregory J. Hannon;Julius Brennecke

  • Identification of Drosophila MicroRNA Targets

    Alexander Stark;Julius Brennecke;Robert B Russell;Stephen M Cohen

  • Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary

    Colin D. Malone;Colin D. Malone;Julius Brennecke;Julius Brennecke;Monica Dus;Monica Dus;Alexander Stark

  • An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

    Julius Brennecke;Colin D. Malone;Alexei A. Aravin;Ravi Sachidanandam

  • A genome-scale shRNA resource for transgenic RNAi in Drosophila

    Jian Quan Ni;Rui Zhou;Rui Zhou;Benjamin Czech;Lu Ping Liu;Lu Ping Liu

  • An endogenous small interfering RNA pathway in Drosophila

    Benjamin Czech;Colin D. Malone;Rui Zhou;Alexander Stark;Alexander Stark

  • Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures

    Alexander Stark;Michael F Lin;Pouya Kheradpour;Jakob Skou Pedersen;Jakob Skou Pedersen

  • Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression

    Grzegorz Sienski;Derya Dönertas;Julius Brennecke

  • The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila.

    Fabio Mohn;Grzegorz Sienski;Dominik Handler;Julius Brennecke

  • piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis

    Fabio Mohn;Dominik Handler;Julius Brennecke

  • Hierarchical rules for Argonaute loading in Drosophila.

    Benjamin Czech;Rui Zhou;Yaniv Erlich;Julius Brennecke

  • An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

    Daniel Olivieri;Martina M Sykora;Ravi Sachidanandam;Karl Mechtler

  • Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila.

    Natascha Bushati;Alexander Stark;Julius Brennecke;Stephen M. Cohen;Stephen M. Cohen

  • The piRNA pathway: a fly's perspective on the guardian of the genome.

    Kirsten-André Senti;Julius Brennecke

  • A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands

    Alexander Stark;Natascha Bushati;Calvin H. Jan;Pouya Kheradpour

  • Principles of MicroRNATarget Recognition

    Julius F. Brennecke;Alexander Stark;Robert B. Russell;Stephen M. Cohen

Frequent Co-Authors

Alexander Stark
Alexander Stark Research Institute of Molecular Pathology
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Stephen M. Cohen
Stephen M. Cohen University of Copenhagen
Ravi Sachidanandam
Ravi Sachidanandam Icahn School of Medicine at Mount Sinai
Maria Novatchkova
Maria Novatchkova University of Vienna
Johannes Zuber
Johannes Zuber Research Institute of Molecular Pathology
Karl Mechtler
Karl Mechtler Research Institute of Molecular Pathology
Alexei A. Aravin
Alexei A. Aravin California Institute of Technology
Robert B. Russell
Robert B. Russell Heidelberg University

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