What is he best known for?
The fields of study he is best known for:
- Cancer
- Immune system
- Internal medicine
His primary scientific interests are in Immunology, Transplantation, Stem cell, Chemotherapy and Hematopoietic stem cell transplantation.
His study focuses on the intersection of Immunology and fields such as Cytotoxic T cell with connections in the field of CD8.
While the research belongs to areas of Transplantation, Robert S. Negrin spends his time largely on the problem of Interleukin 2, intersecting his research to questions surrounding Immune tolerance, Antigen, Priming and Adoptive cell transfer.
As a part of the same scientific study, Robert S. Negrin usually deals with the Stem cell, concentrating on Granulocyte and frequently concerns with Peripheral blood mononuclear cell, Globulin and Platelet.
His research investigates the connection with Chemotherapy and areas like Gastroenterology which intersect with concerns in Myelodysplastic syndromes.
His Hematopoietic stem cell transplantation research is multidisciplinary, incorporating elements of Survival rate and Lymphoma.
His most cited work include:
- CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. (1078 citations)
- Transplantation of bone marrow as compared with peripheral-blood cells from HLA-identical relatives in patients with hematologic cancers (860 citations)
- Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation. (841 citations)
What are the main themes of his work throughout his whole career to date?
Robert S. Negrin focuses on Immunology, Transplantation, Internal medicine, Graft-versus-host disease and Hematopoietic stem cell transplantation.
His study in T cell, IL-2 receptor, Immune system, CD8 and Bone marrow falls within the category of Immunology.
In his work, Regulatory T cell is strongly intertwined with FOXP3, which is a subfield of IL-2 receptor.
His work carried out in the field of CD8 brings together such families of science as Cytotoxic T cell, Cytokine and Molecular biology.
His studies examine the connections between Transplantation and genetics, as well as such issues in Cancer research, with regards to Immunotherapy.
He has included themes like Gastroenterology, Surgery and Oncology in his Internal medicine study.
He most often published in these fields:
- Immunology (55.42%)
- Transplantation (46.83%)
- Internal medicine (27.40%)
What were the highlights of his more recent work (between 2015-2021)?
- Transplantation (46.83%)
- Internal medicine (27.40%)
- Immunology (55.42%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Transplantation, Internal medicine, Immunology, Graft-versus-host disease and Cancer research.
His Transplantation research is multidisciplinary, relying on both Hematopoietic cell, Adoptive cell transfer, IL-2 receptor and CD8.
His Internal medicine study combines topics from a wide range of disciplines, such as Gastroenterology and Oncology.
His Immunology study frequently draws connections between related disciplines such as Stem cell.
His Graft-versus-host disease study also includes fields such as
- Immune system which is related to area like Cytotoxic T cell and Mantle cell lymphoma,
- Cell which intersects with area such as Disease.
His work deals with themes such as T cell, Cell therapy, CD19, Bone marrow and Monoclonal antibody, which intersect with Cancer research.
Between 2015 and 2021, his most popular works were:
- Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells (99 citations)
- Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation. (68 citations)
- TNF-α priming enhances CD4+FoxP3+ regulatory T-cell suppressive function in murine GVHD prevention and treatment (57 citations)
In his most recent research, the most cited papers focused on:
- Cancer
- Immune system
- Internal medicine
Robert S. Negrin mainly investigates Transplantation, Immunology, Immune system, FOXP3 and Graft-versus-host disease.
His Transplantation research entails a greater understanding of Internal medicine.
In the field of Immunology, his study on Pathogenesis, Natural killer T cell and Acquired immune system overlaps with subjects such as Population and In patient.
The various areas that he examines in his Immune system study include Cytotoxic T cell and Hematopoietic stem cell transplantation.
His Graft-versus-host disease study incorporates themes from Corticosteroid, Cytopenia and Ruxolitinib.
His Stem cell research includes themes of Leukemia and Tolerance induction.
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