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Genetics

D-Index
68
Citations
16696
World Ranking
2431
National Ranking
1094

Overview

Marc Lalande is affiliated with the University of Connecticut Health Center in the United States. Their research spans multiple interconnected fields, primarily within biochemistry, genetics, and molecular biology, with additional contributions to medicine and neuroscience. Their work frequently addresses genetic syndromes, imprinting, and the use of pluripotent stem cells in research contexts.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Within these broader disciplines, Lalande's subfields of work cover:

  • Genetics
  • Molecular Biology
  • Pediatrics, Perinatology and Child Health
  • Developmental Neuroscience
  • Cellular and Molecular Neuroscience

The specific topics that recur across their publications are:

  • Genetic Syndromes and Imprinting
  • Prenatal Screening and Diagnostics
  • Pluripotent Stem Cells Research
  • Genetics and Neurodevelopmental Disorders
  • Epigenetics and DNA Methylation
  • Anesthesia and Neurotoxicity Research
  • Neuroscience and Neural Engineering

Marc Lalande has collaborated frequently with colleagues including Maéva Langouët, Dea Gorka, Clarisse Orniacki, Clémence Dupont-Thibert, and Michael Chung.

Their recent publications include:

  • Specific ZNF274 binding interference at SNORD116 activates the maternal transcripts in Prader-Willi syndrome neurons, 2020, Human Molecular Genetics
  • Specific ZNF274 binding interference at SNORD116 activates the maternal transcripts in Prader-Willi syndrome neurons, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Modelling Acute Glucocorticoid Transcriptome Response in Human Embryonic Stem Cell Derived Neural Cultures, 2022, SSRN Electronic Journal
  • Modelling acute glucocorticoid transcriptome response in human embryonic stem cell derived neural cultures, 2023, Stem Cell Research

These publications highlight a focus on genetic regulation mechanisms affecting neural cells and the use of stem cell models to study glucocorticoid responses. Their work contributes to understanding both fundamental molecular processes and clinical conditions related to neurodevelopmental and genetic syndromes.

Best Publications

  • UBE3A/E6-AP mutations cause Angelman syndrome

    Tatsuya Kishino;Marc Lalande;Marc Lalande;Joseph Wagstaff

  • Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome

    Robert D. Nicholls;Joan H. M. Knoll;Merlin G. Butler;Susan Karam

  • Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization.

    Jérôme Cavaillé;Karin Buiting;Martin Kiefmann;Marc Lalande

  • Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion.

    J. H. M. Knoll;J. H. M. Knoll;R. D. Nicholls;R. D. Nicholls;R. E. Magenis;J. M. Graham

  • The Angelman syndrome candidate gene, UBE3A/E6-AP, is imprinted in brain.

    Claire Rougeulle;Claire Rougeulle;Heather Glatt;Marc Lalande;Marc Lalande

  • A strategy to reveal high-frequency RFLPs along the human X chromosome.

    Aldridge J;Kunkel L;Bruns G;Tantravahi U

  • An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript.

    Claire Rougeulle;Carlos Cardoso;Michel Fontés;Laurence Colleaux

  • Analysis of the Set of GABAA Receptor Genes in the Human Genome

    Joseph Simon;Hironobu Wakimoto;Norihisa Fujita;Marc Lalande

  • Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes

    Stormy J. Chamberlain;Pin-Fang Chen;Khong Y. Ng;Fany Bourgois-Rocha

  • Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader–Willi syndrome critical region

    Tayfun Özçelik;Stuart Leff;Wendy Robinson;Tim Donlon

  • Homologous Association of Oppositely Imprinted Chromosomal Domains

    Janine M. LaSalle;Marc Lalande

  • RAB22 and RAB163/mouse BRCA2: Proteins that specifically interact with the RAD51 protein

    Ryushin Mizuta;Janine M. LaSalle;Hwei Ling Cheng;Akira Shinohara

  • The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region.

    P. Jay;C. Rougeulle;A. Massacrier;A. Moncla

  • Imprinting mutations suggested by abnormal DNA methylation patterns in familial Angelman and Prader-Willi syndromes

    A. Reis;B. Dittrich;V. Greger;K. Buiting

  • Allele specificity of DNA replication timing in the Angelman/Prader–Willi syndrome imprinted chromosomal region

    Joan H.M. Knoll;Joan H.M. Knoll;Sou-De Cheng;Marc Lalande;Marc Lalande

  • A reversible arrest point in the late G1 phase of the mammalian cell cycle.

    Marc Lalande

  • Recurrent copy number variations in human induced pluripotent stem cells.

    Kristen Martins-Taylor;Benjamin S Nisler;Seth M Taapken;Tiwanna Compton

  • The Human Magel2 Gene and Its Mouse Homologue Are Paternally Expressed and Mapped to the Prader-Willi Region

    Irène Boccaccio;Heather Glatt-Deeley;Françoise Watrin;Nathalie Roëckel

  • Localization of the gene encoding the GABAA receptor β3 subunit to the Angelman/Prader-Willi region of human chromosome 15

    J. Wagstaff;J. H. M. Knoll;J. Fleming;E. F. Kirkness

  • Regulation of the large (∼1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn

    Miguel Landers;Daria L. Bancescu;Elodie Le Meur;Claire Rougeulle

Frequent Co-Authors

Samuel A. Latt
Samuel A. Latt Boston Children's Hospital
Janine M. LaSalle
Janine M. LaSalle University of California, Davis
Timothy A. Donlon
Timothy A. Donlon University of Hawaii at Manoa
Daniel Sinnett
Daniel Sinnett University of Montreal
Louis M. Kunkel
Louis M. Kunkel Boston Children's Hospital
Robert D. Nicholls
Robert D. Nicholls University of Pittsburgh
Jaan Noolandi
Jaan Noolandi Stanford University
Bernhard Horsthemke
Bernhard Horsthemke University of Duisburg-Essen
Richard G. Miller
Richard G. Miller University of Toronto
André Reis
André Reis University of Erlangen-Nuremberg

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