His primary areas of investigation include Mitochondrion, Biochemistry, Metabolomics, Cell biology and Data science. His Mitochondrion research integrates issues from Malate dehydrogenase, Depolarization and Respiration. His work on Metabolome as part of general Metabolomics research is frequently linked to Molecular medicine, bridging the gap between disciplines.
Bruce S. Kristal combines subjects such as Metabolic effects, Disease, Risk analysis and Mass spectrometry with his study of Metabolome. Bruce S. Kristal has researched Cell biology in several fields, including Programmed cell death and Alpha-synuclein. Bruce S. Kristal interconnects Raw data and Metabolite profiling in the investigation of issues within Data science.
Bruce S. Kristal spends much of his time researching Mitochondrion, Biochemistry, Internal medicine, Mitochondrial permeability transition pore and Metabolomics. His Mitochondrion research is multidisciplinary, incorporating perspectives in Oxidative stress, Programmed cell death and Neuroprotection. The study incorporates disciplines such as Gastroenterology, Endocrinology and Cardiology in addition to Internal medicine.
His research integrates issues of Cyclosporin a, Biophysics and Calcium in his study of Mitochondrial permeability transition pore. His Metabolomics research includes elements of Disease and Mass spectrometry. As part of one scientific family, Bruce S. Kristal deals mainly with the area of Metabolome, narrowing it down to issues related to the Cohort, and often Epidemiology.
Bruce S. Kristal mainly investigates Internal medicine, Endocrinology, Cell biology, Pathology and Adipose tissue. His work on Calorie restriction and Multiethnic cohort as part of general Internal medicine study is frequently linked to mTORC1 and Tissue membrane, bridging the gap between disciplines. His study in Endocrinology is interdisciplinary in nature, drawing from both Minor allele frequency and Fatty liver.
His Mitochondrion study in the realm of Cell biology interacts with subjects such as Calcium buffering. His research in Mitochondrion intersects with topics in Caspase 3, Reactive oxygen species, Neurite, Neurodegeneration and Depolarization. His work carried out in the field of Metabolomics brings together such families of science as Liquid chromatography–mass spectrometry and Mass spectrometry.
The scientist’s investigation covers issues in Metabolomics, Disease, Cell biology, Mass spectrometry and Cohort. His Metabolomics study combines topics from a wide range of disciplines, such as Biological system, Analyte and Liquid chromatography–mass spectrometry. His studies deal with areas such as Computational biology and Bioinformatics as well as Disease.
His Cell biology study incorporates themes from Mitochondrial permeability transition pore, Biochemistry and Reverse electron flow. His Mass spectrometry research is classified as research in Chromatography. The concepts of his Cohort study are interwoven with issues in Metabolome, Interquartile range, Epidemiology and Gerontology.
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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
Shan Zhu;Irina G. Stavrovskaya;Martin Drozda;Martin Drozda;Betty Y. S. Kim;Betty Y. S. Kim.
Metabolomics: A Global Biochemical Approach to Drug Response and Disease
Rima Kaddurah-Daouk;Bruce S. Kristal;Richard M. Weinshilboum.
Annual Review of Pharmacology and Toxicology (2008)
Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research
Augustin Scalbert;Lorraine Brennan;Oliver Fiehn;Thomas Hankemeier.
Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease.
Xin Wang;Shan Zhu;Martin Drozda;Wenhua Zhang.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.
Tie Shan Tang;Elizabeth Slow;Vitalie Lupu;Irina G. Stavrovskaya.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Proposed minimum reporting standards for data analysis in metabolomics
Royston Goodacre;David Broadhurst;Age K. Smilde;Bruce S. Kristal.
The metabolomics standards initiative (MSI)
Oliver Fiehn;Don Robertson;Jules Griffin;Mariet vab der Werf.
MULTIPLE ROLES OF GLUTATHIONE IN THE CENTRAL NERVOUS SYSTEM
A. J. L. Cooper;B. S. Kristal.
Biological Chemistry (1997)
The Metabolomics Standards Initiative
Susanna Assunta Sansone;Teresa Fan;Royston Goodacre;Julian L. Griffin.
Nature Biotechnology (2007)
An emerging hypothesis: synergistic induction of aging by free radicals and Maillard reactions.
Bruce S. Kristal;Byung P. Yu.
Journal of Gerontology (1992)
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