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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
16541
World Ranking
9083
National Ranking
4035

Overview

Bruce S. Kristal is affiliated with Brigham and Women's Hospital in the United States and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their work spans multiple subfields, including molecular biology, physiology, nutrition and dietetics, biological psychiatry, and artificial intelligence.

The primary focus areas of Bruce S. Kristal's research include metabolomics and mass spectrometry studies, tryptophan and brain disorders, diet and metabolism studies, gut microbiota and health, liver disease diagnosis and treatment, nutritional studies and diet, and stress responses and cortisol.

Bruce S. Kristal has authored research published in journals such as Brain Behavior and Immunity, PLoS ONE, Gut Microbes, Hepatology Communications, and Cancer Epidemiology Biomarkers & Prevention. Notable recent papers include:

  • Metabolomic and inflammatory signatures of symptom dimensions in major depression, 2022, Brain Behavior and Immunity
  • The gut microbiome and type 2 diabetes status in the Multiethnic Cohort, 2021, PLoS ONE
  • Associations of the gut microbiome with hepatic adiposity in the Multiethnic Cohort Adiposity Phenotype Study, 2021, Gut Microbes
  • Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study, 2020, Hepatology Communications
  • Circulating Biomarker Score for Visceral Fat and Risks of Incident Colorectal and Postmenopausal Breast Cancer: The Multiethnic Cohort Adiposity Phenotype Study, 2020, Cancer Epidemiology Biomarkers & Prevention

Frequent co-authors collaborating with Kristal include Lynne R. Wilkens, Loïc Le Marchand, Matthew J. Sniatynski, Tamar Sofer, and Gertraud Maskarinec.

Kristal's research has been published repeatedly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Patterns, UNC Libraries, PLoS ONE, and Cancer Epidemiology Biomarkers & Prevention.

Their expertise integrates advanced analytical techniques in molecular biology with clinical and epidemiological investigations. The scope of their work demonstrates a significant involvement in the analysis of metabolic processes, gut microbiota interactions, and related health outcomes.

Best Publications

  • Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

    Shan Zhu;Irina G. Stavrovskaya;Martin Drozda;Martin Drozda;Betty Y. S. Kim;Betty Y. S. Kim

  • Metabolomics: A Global Biochemical Approach to Drug Response and Disease

    Rima Kaddurah-Daouk;Bruce S. Kristal;Richard M. Weinshilboum

  • Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research

    Augustin Scalbert;Lorraine Brennan;Oliver Fiehn;Thomas Hankemeier

  • The metabolomics standards initiative (MSI)

    Oliver Fiehn;Don Robertson;Jules Griffin;Mariet vab der Werf

  • Proposed minimum reporting standards for data analysis in metabolomics

    Royston Goodacre;David Broadhurst;Age K. Smilde;Bruce S. Kristal

  • Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease.

    Xin Wang;Shan Zhu;Martin Drozda;Wenhua Zhang

  • Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease.

    Tie Shan Tang;Elizabeth Slow;Vitalie Lupu;Irina G. Stavrovskaya

  • The Metabolomics Standards Initiative

    Susanna Assunta Sansone;Teresa Fan;Royston Goodacre;Julian L. Griffin

  • MULTIPLE ROLES OF GLUTATHIONE IN THE CENTRAL NERVOUS SYSTEM

    A. J. L. Cooper;B. S. Kristal

  • Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.

    M. C. Cornelis;E. M. Byrne;T. Esko;M. A. Nalls

  • Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction.

    Eric S. Luth;Irina G. Stavrovskaya;Tim Bartels;Bruce S. Kristal

  • An emerging hypothesis: synergistic induction of aging by free radicals and Maillard reactions.

    Bruce S. Kristal;Byung P. Yu

  • High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation.

    Mary F. Lopez;Bruce S. Kristal;Elena Chernokalskaya;Alexander Lazarev

  • 4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition.

    Bruce S. Kristal;Brian K. Park;Byung P. Yu

  • Consensus scoring criteria for improving enrichment in virtual screening.

    Jinn-Moon Yang;Yen Fu Chen;Tsai Wei Shen;Bruce S. Kristal

  • Mitochondrial Permeability Transition in the Central Nervous System: Induction by Calcium Cycling‐Dependent and ‐Independent Pathways

    Bruce S. Kristal;Janet M. Dubinsky

  • Zn2+ Inhibits α-Ketoglutarate-stimulated Mitochondrial Respiration and the Isolated α-Ketoglutarate Dehydrogenase Complex *

    Abraham M. Brown;Bruce S. Kristal;Michelle S. Effron;Alexander I. Shestopalov

  • Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases.

    William J Burke;Shu Wen Li;Hyung D Chung;David A Ruggiero

  • Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease

    Robert J. Ferrante;Hoon Ryu;Hoon Ryu;James K. Kubilus;James K. Kubilus;Santosh D'Mello

  • Lipidomics profiling by high-resolution LC-MS and high-energy collisional dissociation fragmentation: focus on characterization of mitochondrial cardiolipins and monolysocardiolipins.

    Susan S. Bird;Vasant R. Marur;Vasant R. Marur;Matthew J. Sniatynski;Matthew J. Sniatynski;Heather K. Greenberg;Heather K. Greenberg

Frequent Co-Authors

Byung Pal Yu
Byung Pal Yu The University of Texas Health Science Center at San Antonio
Johanna W. Lampe
Johanna W. Lampe Fred Hutchinson Cancer Research Center
Loic Le Marchand
Loic Le Marchand University of Hawaii at Manoa
Lynne R. Wilkens
Lynne R. Wilkens University of Hawaii at Manoa
John P. Blass
John P. Blass Cornell University
M. Flint Beal
M. Flint Beal Cornell University
Robert J. Ferrante
Robert J. Ferrante Boston University
Walter C. Willett
Walter C. Willett Harvard University
John A. Shepherd
John A. Shepherd University of Hawaii at Manoa
Susan E. Hankinson
Susan E. Hankinson University of Massachusetts Amherst

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