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M. Alexander Schmidt

M. Alexander Schmidt

D-Index & Metrics

Microbiology

D-Index
63
Citations
11572
World Ranking
2800
National Ranking
212

Overview

M. Alexander Schmidt is affiliated with the University of Münster in Germany. Their research spans multiple disciplines, primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's work notably integrates subfields such as Molecular Biology, Cell Biology, Immunology, Oncology, and Epidemiology.

Their research topics cover various aspects of molecular and cellular processes, with focused studies on:

  • Wnt/β-catenin signaling in development and cancer
  • Eosinophilic Disorders and Syndromes
  • Polyomavirus and related diseases
  • Chronic Myeloid Leukemia Treatments
  • Extracellular vesicles in disease
  • Nanoplatforms for cancer theranostics
  • Immune cells in cancer

Recent publication venues for M. Alexander Schmidt include a variety of specialized journals:

  • SSRN Electronic Journal
  • Journal of Virology
  • Molecular Imaging and Biology
  • Science Signaling
  • The Journal of Cell Biology

The scholar has contributed to significant research articles such as:

  • "Epidermal Growth Factor Receptor and Abl2 Kinase Regulate Distinct Steps of Human Papillomavirus 16 Endocytosis," 2020, Journal of Virology
  • "Tracking of Tumor Cell-Derived Extracellular Vesicles In Vivo Reveals a Specific Distribution Pattern with Consecutive Biological Effects on Target Sites of Metastasis," 2020, Molecular Imaging and Biology
  • "Intestinal brush border formation requires a TMIGD1-based intermicrovillar adhesion complex," 2022, Science Signaling
  • "A JAM-A-tetraspanin-αvβ5 integrin complex regulates contact inhibition of locomotion," 2022, The Journal of Cell Biology
  • "Discrete spatio-temporal regulation of tyrosine phosphorylation directs influenza A virus M1 protein towards its function in virion assembly," 2020, PLoS Pathogens

The scientist has collaborated frequently with peers including Lilo Greune, Volker Gerke, Klaus Ebnet, Christian Hartmann, and Eva-Maria Thüring. These collaborations reflect interdisciplinary efforts in molecular and cell biology research.

Best Publications

  • Molecular mechanisms underlying the probiotic effects of Escherichia coli Nissle 1917 involve ZO-2 and PKCzeta redistribution resulting in tight junction and epithelial barrier repair.

    Agata A. Zyrek;Christoph Cichon;Simone Helms;Corinne Enders

  • The structure of the capsular polysaccharide (K5 antigen) of urinary-tract-infective Escherichia coli 010:K5:H4. A polymer similar to desulfo-heparin.

    Willie F. Vann;M. Alexander Schmidt;Barbara Jann;Klaus Jann

  • Analysis of collection of hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli

    Alexander Mellmann;Martina Bielaszewska;Robin Köck;Alexander W Friedrich

  • Identification of unconventional intestinal pathogenic Escherichia coli isolates expressing intermediate virulence factor profiles by using a novel single-step multiplex PCR

    Daniel Müller;Lilo Greune;Gerhard Heusipp;Helge Karch

  • Never say never again: protein glycosylation in pathogenic bacteria.

    Inga Benz;M. Alexander Schmidt

  • Sweet new world: glycoproteins in bacterial pathogens

    M.Alexander Schmidt;Lee W. Riley;Inga Benz

  • Characterization of translocation pores inserted into plasma membranes by type III‐secreted Esp proteins of enteropathogenic Escherichia coli

    Unknown

  • Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury.

    Martina Bielaszewska;Christian Rüter;Andreas Bauwens;Lilo Greune

  • Enterohemorrhagic Escherichia coli hemolysin employs outer membrane vesicles to target mitochondria and cause endothelial and epithelial apoptosis

    Martina Bielaszewska;Christian Rüter;Lisa Kunsmann;Lilo Greune

  • Glycosylation with heptose residues mediated by the aah gene product is essential for adherence of the AIDA-I adhesin.

    Inga Benz;M. Alexander Schmidt

  • A novel staphylococcal internalization mechanism involves the major autolysin Atl and heat shock cognate protein Hsc70 as host cell receptor.

    Nina Hirschhausen;Tim Schlesier;M. Alexander Schmidt;Friedrich Götz

  • LEEways: tales of EPEC, ATEC and EHEC

    M. Alexander Schmidt

  • AIDA‐I, the adhesin involved in diffuse adherence of the diarrhoeagenic Escherichia coli strain 2787 (O126:H27), is synthesized via a precursor molecule

    Unknown

  • Cytolethal Distending Toxin Gene Cluster in Enterohemorrhagic Escherichia coli O157:H− and O157:H7: Characterization and Evolutionary Considerations

    Andreas Janka;Martina Bielaszewska;Ulrich Dobrindt;Lilo Greune

  • Characterization of Escherichia coli Isolates from Hospital Inpatients or Outpatients with Urinary Tract Infection

    Francisco Toval;Christian-Daniel Köhler;Ulrich Vogel;Florian Wagenlehner

  • Role of M cells in intestinal barrier function.

    T. Kucharzik;N. Lügering;K. Rautenberg;A. Lügering

  • Virulence from vesicles : Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain

    Lisa Kunsmann;Christian Rüter;Andreas Bauwens;Lilo Greune

  • Phospholipid substitution of capsular (K) polysaccharide antigens from Escherichia coli causing extraintestinal infections

    M. Alexander Schmidt;K. Jann

  • DNA adenine methylation and bacterial pathogenesis.

    Gerhard Heusipp;Stefan Fälker;M Alexander Schmidt

  • Shiga Toxin 2e-Producing Escherichia coli Isolates from Humans and Pigs Differ in Their Virulence Profiles and Interactions with Intestinal Epithelial Cells

    Anne-Katharina Sonntag;Martina Bielaszewska;Alexander Mellmann;Nadine Dierksen

  • Differential targeting of the E-Cadherin/β-Catenin complex by gram-positive probiotic lactobacilli improves epithelial barrier function.

    Stephanie Hummel;Katharina Veltman;Christoph Cichon;Ulrich Sonnenborn

  • Shiga Toxin-Negative Attaching and Effacing Escherichia coli: Distinct Clinical Associations with Bacterial Phylogeny and Virulence Traits and Inferred In-Host Pathogen Evolution

    Martina Bielaszewska;Barbara Middendorf;Robin Köck;Alexander W Friedrich

  • Characterization of cytolethal distending toxin genes and expression in shiga toxin-producing Escherichia coli strains of non-O157 serogroups.

    Martina Bielaszewska;Marina Fell;Lilo Greune;Rita Prager

Frequent Co-Authors

Helge Karch
Helge Karch University of Münster
Martina Bielaszewska
Martina Bielaszewska University of Münster
Alexander Mellmann
Alexander Mellmann University of Münster
Alexander W. Friedrich
Alexander W. Friedrich University Medical Center Groningen
Angelika Fruth
Angelika Fruth Robert Koch Institute
Ulrich Dobrindt
Ulrich Dobrindt University of Münster
Kwang Sik Kim
Kwang Sik Kim Johns Hopkins University School of Medicine
Dag Harmsen
Dag Harmsen University of Münster
Robin Köck
Robin Köck Essen University Hospital
Jasna Peter-Katalinić
Jasna Peter-Katalinić University of Münster

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