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Mary E. Klotman

Mary E. Klotman

D-Index & Metrics

Microbiology

D-Index
62
Citations
12999
World Ranking
2889
National Ranking
1149

Research.com Recognitions

  • 2014 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Mary E. Klotman is affiliated with Duke University in the United States. Their research spans multiple domains within medicine, with a significant focus on HIV research and treatment. Their work encompasses virology, infectious diseases, genetics, and molecular biology, with a notable emphasis on HIV/AIDS research and interventions.

Their recent publications reflect a broad engagement with the study of HIV and related viral infections. Selected recent papers include:

  • Detection of Donor's HIV Strain in HIV-Positive Kidney-Transplant Recipient (2020), published in the New England Journal of Medicine
  • Skeletal Muscle Is an Antigen Reservoir in Integrase-Defective Lentiviral Vector-Induced Long-Term Immunity (2020), published in Molecular Therapy - Methods & Clinical Development
  • Tubular-specific expression of HIV protein Vpr leads to severe tubulointerstitial damage accompanied by progressive fibrosis and cystic development (2022), published in Kidney International
  • Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages (2020), published in AIDS
  • Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs (2020), published in npj Vaccines

Mary E. Klotman has frequently published in the following venues:

  • Journal of Clinical Investigation
  • npj Vaccines
  • Molecular Therapy - Methods & Clinical Development
  • bioRxiv (Cold Spring Harbor Laboratory)
  • New England Journal of Medicine

Their research collaborations include repeated partnerships with these co-authors:

  • Maria Blasi
  • Andrea Cara
  • Donatella Negri
  • Hannah Stadtler
  • Kelly T. Hughes

The primary fields of study for Mary E. Klotman include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Their subfields of research emphasize:

  • Virology
  • Infectious Diseases
  • Genetics
  • Epidemiology
  • Molecular Biology

Main topics addressed in their work cover:

  • HIV Research and Treatment
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • Virus-based gene therapy research
  • Herpesvirus Infections and Treatments
  • CAR-T cell therapy research
  • Cytomegalovirus and herpesvirus research

Mary E. Klotman has been recognized by professional organizations, including membership in the National Academy of Medicine since 2014 and the Association of American Physicians.

Best Publications

  • Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease.

    Paolo A. Hernandez;Robert J. Gorlin;John N. Lukens;Shoichiro Taniuchi

  • Defensins in innate antiviral immunity

    Mary E. Klotman;Theresa L. Chang

  • Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection.

    Jonathan A. Winston;Leslie A. Bruggeman;Michael D. Ross;Jeffrey Jacobson

  • Renal Epithelium Is a Previously Unrecognized Site of HIV-1 Infection

    Leslie A. Bruggeman;Michael D. Ross;Nozomu Tanji;Andrea Cara

  • Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy

    Daniele Marras;Leslie A Bruggeman;Feng Gao;Nozomu Tanji

  • Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes.

    Jeffrey B. Kopp;Mary E. Klotman;Scott H. Adler;Leslie A. Bruggeman

  • Dual role of α-defensin-1 in anti–HIV-1 innate immunity

    Theresa L. Chang;Jesus Vargas;Armando DelPortillo;Mary E. Klotman

  • Highly Active Antiretroviral Therapy and the Epidemic of HIV+ End-Stage Renal Disease

    Elissa J. Schwartz;Elissa J. Schwartz;Lynda A. Szczech;Michael J. Ross;Mary E. Klotman

  • Protein isoforms encoded by the pX region of human T-cell leukemia/lymphotropic virus type I.

    I J Koralnik;A Gessain;M E Klotman;A Lo Monico

  • Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes

    Mary E. Klotman;Sunyoung Kim;Aby Buchbinder;Anita DeRossi

  • Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

    Charles R. Swanepoel;Mohamed G. Atta;Vivette D. D’Agati;Michelle M. Estrella

  • Acute renal failure in hospitalized patients with HIV : risk factors and impact on in-hospital mortality

    Christina M Wyatt;Raymond R Arons;Paul E Klotman;Mary E Klotman

  • HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection

    Jonathan A. Winston;Mary E. Klotman;Paul E. Klotman

  • Chronic kidney disease in HIV infection: an urban epidemic.

    Christina M Wyatt;Jonathan A Winston;Carlos D Malvestutto;Dawn A Fishbein

  • Prophylactic Intravenous Amphotericin B in Neutropenic Autologous Bone Marrow Transplant Recipients

    John R. Perfect;Mary E. Klotman;Mary E. Klotman;Colleen C. Gilbert;Denise D. Crawford

  • Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults

    Jeffrey M. Jacobson;Israel Lowy;Courtney V. Fletcher;Tobias J. O'Neill

  • Expression of alternatively spliced human T-lymphotropic virus type I pX mRNA in infected cell lines and in primary uncultured cells from patients with adult T-cell leukemia/lymphoma and healthy carriers

    Zwi N. Berneman;Ronald B. Gartenhaus;Marvin S. Reitz;William A. Blattner

  • Novel Integrase-Defective Lentiviral Episomal Vectors for Gene Transfer

    Jr J Vargas;GL Gusella;V Najfeld;ME Klotman

  • Human Immunodeficiency Virus (HIV)-1 Infects Human Hepatic Stellate Cells and Promotes Collagen I and Monocyte Chemoattractant Protein-1 Expression: Implications for the Pathogenesis of HIV/Hepatitis C Virus–Induced Liver Fibrosis

    Ana C. Tuyama;Feng Hong;Yedidya Saiman;Chuansheng Wang

  • β-Defensin Inhibits Influenza Virus Replication by Cell-Mediated Mechanism(s)

    Mirella Salvatore;Adolfo García-Sastre;Piotr Ruchala;Robert I. Lehrer

  • Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways

    John Cijiang He;Mohammad Husain;Masaaki Sunamoto;Vivette D. D’Agati

Frequent Co-Authors

Michael W. Ross
Michael W. Ross University of Minnesota
Vivette D. D'Agati
Vivette D. D'Agati Columbia University
Sampa Santra
Sampa Santra Beth Israel Deaconess Medical Center
Celia C. LaBranche
Celia C. LaBranche Duke University
Barton F. Haynes
Barton F. Haynes Duke University
Betsy C. Herold
Betsy C. Herold Albert Einstein College of Medicine
Robert C. Gallo
Robert C. Gallo University of South Florida
feng gao
feng gao Duke University
Genoveffa Franchini
Genoveffa Franchini National Institutes of Health
Hynda K. Kleinman
Hynda K. Kleinman George Washington University

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