World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
52
Citations
13343
World Ranking
4033
National Ranking
191

Overview

Salvatore Valitutti is a researcher affiliated with the Federal University of Toulouse Midi-Pyrénées in France. Their work primarily spans the fields of Immunology and Microbiology, as well as Biochemistry, Genetics, and Molecular Biology. Within these domains, Valitutti's research focuses on specialized subfields such as Immunology, Molecular Biology, Oncology, Cell Biology, and Biophysics.

The main topics addressed in Valitutti's publications include:

  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • Mast cells and histamine
  • CAR-T cell therapy research
  • Cellular transport and secretion
  • RNA Interference and Gene Delivery

Valitutti has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Frontiers in Immunology, Zenodo (CERN European Organization for Nuclear Research), and Science. This reflects a broad engagement with both preprint and peer-reviewed platforms.

Some of Valitutti's recent papers include:

  • Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells, 2020, Science
  • Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes, 2022, Nature Communications
  • Evolutionary design of explainable algorithms for biomedical image segmentation, 2023, Nature Communications
  • Self-activation of Vγ9Vδ2 T cells by exogenous phosphoantigens involves TCR and butyrophilins, 2021, Cellular and Molecular Immunology
  • Resisting T cell attack: tumor-cell-intrinsic defense and reparation mechanisms, 2022, Trends in cancer

Valitutti has collaborated extensively with several researchers, indicating a network of frequent coauthors. These include Sabina Müller, Michael L. Dustin, Cosima T. Baldari, Brienne McKenzie, and Éric Espinosa, with coauthorship counts ranging from seven to eleven publications each.

Best Publications

  • Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.

    Nils Holler;Rossana Zaru;Olivier Micheau;Margot Thome

  • Serial triggering of many T-cell receptors by a few peptide–MHC complexes

    Salvatore Valitutti;Sabina Müller;Marina Cella;Elisabetta Padovan

  • SUSTAINED SIGNALING LEADING TO T CELL ACTIVATION RESULTS FROM PROLONGED T CELL RECEPTOR OCCUPANCY. ROLE OF T CELL ACTIN CYTOSKELETON

    Salvatore Valitutti;Mark Dessing;Klaus Aktories;Harald Gallati

  • Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

    S Valitutti;S Müller;M Dessing;A Lanzavecchia

  • CARMA1 is a critical lipid raft- associated regulator of TCR-induced NF-κB activation

    Olivier Gaide;Benoît Favier;Daniel F. Legler;David Bonnet

  • A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells.

    Jun Huang;Mario Brameshuber;Xun Zeng;Jianming Xie

  • Degradation of T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation

    Salvatore Valitutti;Sabina Müller;Mariolina Salio;Antonio Lanzavecchia

  • Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines.

    S Sozzani;F Sallusto;W Luini;D Zhou

  • Different activation signals induce distinct mast cell degranulation strategies

    Nicolas Gaudenzio;Riccardo Sibilano;Thomas Marichal;Philipp Starkl

  • Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

    Wong Yu;Ning Jiang;Peter J.R. Ebert;Brian A. Kidd

  • Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition

    Salvatore Valitutti;Antonio Lanzavecchia

  • Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: Manifestation of a dual activation threshold

    Mustapha Faroudi;Clemens Utzny;Mariolina Salio;Vincenzo Cerundolo

  • HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes.

    M P Zanni;S von Greyerz;B Schnyder;K A Brander

  • Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses.

    Aurelie Wiedemann;David Depoil;Mustapha Faroudi;Salvatore Valitutti

  • Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes.

    Olivier Leupin;Rossana Zaru;Thierry Laroche;Sabina Müller

  • Immunological Synapses Are Versatile Structures Enabling Selective T Cell Polarization

    David Depoil;Rossana Zaru;Martine Guiraud;Anne Chauveau

  • Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

    Š. Bálint;S. Müller;R. Fischer;B. M. Kessler

  • Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion.

    Elisabetta Padovan;Claudia Giachino;Marina Cella;Salvatore Valitutti

  • Cutting Edge: T Lymphocyte Activation by Repeated Immunological Synapse Formation and Intermittent Signaling

    Mustapha Faroudi;Rossana Zaru;Pierre Paulet;Sabina Müller

  • An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse

    Florie Bertrand;Sabina Müller;Sabina Müller;Kyung-Ho Roh;Camille Laurent;Camille Laurent

  • A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion

    Jun Huang;Mario Brameshuber;Xun Zeng;Jianming Xie

  • Degradation of T Cell Receptor (TCR)-CD3- z Complexes after Antigenic Stimulation

    Salvatore Valitutti;Sabina Müller;Mariolina Salio;Antonio Lanzavecchia

Frequent Co-Authors

Antonio Lanzavecchia
Antonio Lanzavecchia Istituto Nazionale Genetica Molecolare
Piero Musiani
Piero Musiani University of Chieti-Pescara
Luigi Maria Larocca
Luigi Maria Larocca Catholic University of the Sacred Heart
Daniela Corda
Daniela Corda National Academies of Sciences, Engineering, and Medicine
Mark M. Davis
Mark M. Davis Stanford University
Qi-Jing Li
Qi-Jing Li Duke University
Mariolina Salio
Mariolina Salio University of Oxford
Mayte Villalba
Mayte Villalba Complutense University of Madrid
Noriyo Nagata
Noriyo Nagata National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in advancing their career in Immunology, exploring related healthcare degrees can open new opportunities. Nursing paths such as nurse practitioners (NPs) offer specialized roles that complement immunological research and clinical practice.

One important factor for prospective students is finding the easiest np programs to get into. These programs provide accessible entry points while maintaining quality education. Additionally, programs that offer excellent hands-on experience, like the online pmhnp programs with clinical placement, are crucial for gaining practical skills essential in healthcare settings.

Cost is another vital consideration. Many students seek affordability without sacrificing program integrity, making the cheapest psych np programs online attractive options for budgeting their education.

Finally, understanding future earnings potential is key. The dnp salary varies by location, informing career decisions for those pursuing a Doctor of Nursing Practice degree alongside immunology expertise.

Best Scientists Citing Salvatore Valitutti

Trending Scientists