Niels Mailand

Overview

Best Publications

• The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.

  Jacob Falck;Niels Mailand;Randi G. Syljuåsen;Jiri Bartek

  1472
  Citations

• RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

  Niels Mailand;Simon Bekker-Jensen;Helene Faustrup;Fredrik Melander

  1322
  Citations

• RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

  Carsten Doil;Niels Mailand;Simon Bekker-Jensen;Patrice Menard

  1059
  Citations

• Rapid destruction of human Cdc25A in response to DNA damage.

  Niels Mailand;Jacob Falck;Claudia Lukas;Randi G. Syljuåsen

  1057
  Citations

• ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

  Luis Ignacio Toledo;Matthias Altmeyer;Maj-Britt Rask;Claudia Lukas

  876
  Citations

• Regulation of G2/M events by Cdc25A through phosphorylation‐dependent modulation of its stability

  Niels Mailand;Alexandre V. Podtelejnikov;Anja Groth;Matthias Mann

  459
  Citations

• DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

  Rajat Gupta;Kumar Somyajit;Takeo Narita;Elina Maskey

  430
  Citations

• Regulation of PCNA-protein interactions for genome stability.

  Niels Mailand;Ian Gibbs-Seymour;Simon Bekker-Jensen

  423
  Citations

• Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase.

  Alwin Krämer;Niels Mailand;Claudia Lukas;Randi G. Syljuåsen

  418
  Citations

• CDKs Promote DNA Replication Origin Licensing in Human Cells by Protecting Cdc6 from APC/C-Dependent Proteolysis

  Niels Mailand;John F.X. Diffley

  414
  Citations

• Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

  Tina Thorslund;Anita Ripplinger;Saskia Hoffmann;Thomas Wild

  407
  Citations

• The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

  Rune Busk Damgaard;Ueli Nachbur;Ueli Nachbur;Ueli Nachbur;Monica Yabal;Wendy Wei-Lynn Wong;Wendy Wei-Lynn Wong

  396
  Citations

• Assembly and function of DNA double-strand break repair foci in mammalian cells

  Simon Bekker-Jensen;Niels Mailand

  394
  Citations

• Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

  Petra Schwertman;Simon Bekker-Jensen;Niels Mailand

  364
  Citations

• Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

  Jannie M.R. Danielsen;Kathrine B. Sylvestersen;Simon Bekker-Jensen;Damian Szklarczyk

  362
  Citations

• HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

  Simon Bekker-Jensen;Jannie Rendtlew Danielsen;Kasper Fugger;Irina Gromova

  354
  Citations

• TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

  Thorkell Gudjonsson;Matthias Altmeyer;Velibor Savic;Luis Toledo

  348
  Citations

• The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks

  Mayura Meerang;Danilo Ritz;Danilo Ritz;Shreya Paliwal;Zuzana Garajova

  303
  Citations

• Destruction of Claspin by SCFβTrCP Restrains Chk1 Activation and Facilitates Recovery from Genotoxic Stress

  Niels Mailand;Simon Bekker-Jensen;Jiri Bartek;Jiri Lukas

  298
  Citations

• Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.

  Lou K. Povlsen;Petra Beli;Sebastian A. Wagner;Sara L. Poulsen

  286
  Citations