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Matthias Altmeyer

Matthias Altmeyer

D-Index & Metrics

Molecular Biology

D-Index
46
Citations
9935
World Ranking
2799
National Ranking
51

Overview

Matthias Altmeyer is affiliated with the University of Zurich in Switzerland. Their research focuses primarily on biochemistry, genetics, and molecular biology, with contributions also in medicine. The main subfields of study for Altmeyer include molecular biology, oncology, genetics, plant science, and cancer research.

The scientist's work covers a range of research topics, notably DNA repair mechanisms, CRISPR and genetic engineering, genomics and chromatin dynamics, PARP inhibition in cancer therapy, RNA research and splicing, cancer-related molecular pathways, and calcium signaling and nucleotide metabolism.

Altmeyer has published extensively in several scientific venues, contributing the most to Nature Communications, followed by Molecular Cell, bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, and Nature.

  • Nature Communications (6 publications)
  • Molecular Cell (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Cell Reports (2 publications)
  • Nature (2 publications)

Recent papers by Matthias Altmeyer include the following:

  • "ADP-ribosyltransferases, an update on function and nomenclature," 2021, FEBS Journal
  • "The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency," 2020, Cell Reports
  • "Activation of homologous recombination in G1 preserves centromeric integrity," 2021, Nature
  • "Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma," 2021, Nature Cancer
  • "Sequential role of RAD51 paralog complexes in replication fork remodeling and restart," 2020, Nature Communications

Altmeyer has also contributed to the publication of books, including "Protecting the Code: DNA Double-Strand Break Repair Pathway Choice," published by Frontiers Media in 2023.

Frequent collaborators in Altmeyer's research include Vincent Spegg, Ανδρέας Παναγόπουλος, Marco Gatti, Ralph Imhof, and Aleksandra Lezaja.

Best Publications

  • ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Luis Ignacio Toledo;Matthias Altmeyer;Maj-Britt Rask;Claudia Lukas

  • Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

    Matthias Altmeyer;Matthias Altmeyer;Kai J. Neelsen;Federico Teloni;Irina Pozdnyakova

  • Complete genome sequence of the myxobacterium Sorangium cellulosum

    Susanne Schneiker;Olena Perlova;Olaf Kaiser;Klaus Gerth

  • A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation.

    Gyula Timinszky;Susanne Till;Paul O Hassa;Michael Hothorn

  • Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

    Matthias Altmeyer;Simon Messner;Paul O. Hassa;Monika Fey

  • Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding

    Gad Asher;Hans Reinke;Matthias Altmeyer;Maria Gutierrez-Arcelus

  • Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

    Stephanie Jungmichel;Florian Rosenthal;Matthias Altmeyer;Jiri Lukas

  • Phase separation of 53BP1 determines liquid-like behavior of DNA repair compartments.

    Sinan Kilic;Aleksandra Lezaja;Marco Gatti;Eliana Bianco

  • TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

    Thorkell Gudjonsson;Matthias Altmeyer;Velibor Savic;Luis Toledo

  • PARP1 ADP-ribosylates lysine residues of the core histone tails

    Simon Messner;Matthias Altmeyer;Hongtao Zhao;Andrea Pozivil

  • Phase Separation: Linking Cellular Compartmentalization to Disease

    Adriano Aguzzi;Matthias Altmeyer

  • ADP-ribosyltransferases, an update on function and nomenclature

    Bernhard Lüscher;Ivan Ahel;Matthias Altmeyer;Alan Ashworth

  • 53BP1 fosters fidelity of homology-directed DNA repair

    Fena Ochs;Kumar Somyajit;Matthias Altmeyer;Maj-Britt Druedahl Rask

  • Readers of poly(ADP-ribose): designed to be fit for purpose

    Federico Teloni;Matthias Altmeyer

  • Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length.

    Jörg Fahrer;Ramon Kranaster;Matthias Altmeyer;Andreas H Marx

  • A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells.

    Akshay K. Ahuja;Karolina Jodkowska;Federico Teloni;Anna H. Bizard

  • The NBS1–Treacle complex controls ribosomal RNA transcription in response to DNA damage

    Dorthe H Larsen;Flurina J. Hari;Julie A. Clapperton;Myriam Gwerder

  • Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin

    Stefania Pellegrino;Jone Michelena;Federico Teloni;Ralph Imhof

  • A Mechanism for Controlled Breakage of Under-replicated Chromosomes during Mitosis.

    Heike Duda;Meret Arter;Jiradet Gloggnitzer;Federico Teloni

  • Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance.

    Jone Michelena;Aleksandra Lezaja;Federico Teloni;Thomas Schmid

Frequent Co-Authors

Michael O. Hottiger
Michael O. Hottiger University of Zurich
Jiri Lukas
Jiri Lukas University of Copenhagen
Rolf Müller
Rolf Müller Saarland University
Claudia Lukas
Claudia Lukas University of Copenhagen
Michael L. Nielsen
Michael L. Nielsen University of Copenhagen
Magnar Bjørås
Magnar Bjørås Norwegian University of Science and Technology
Grigory L. Dianov
Grigory L. Dianov Novosibirsk State University
Helge B. Bode
Helge B. Bode Goethe University Frankfurt
Jiri Bartek
Jiri Bartek Karolinska Institute
Matthias Dobbelstein
Matthias Dobbelstein University of Göttingen

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