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Michael L. Nielsen

Michael L. Nielsen

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
20748
World Ranking
9001
National Ranking
88

Overview

Michael L. Nielsen is affiliated with the University of Copenhagen in Denmark. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with a notable output in related areas such as Medicine.

Their work spans several subfields including Molecular Biology, Oncology, Immunology, Physiology, and Electrical and Electronic Engineering. The main topics addressed in their research involve:

  • PARP inhibition in cancer therapy
  • DNA Repair Mechanisms
  • Ubiquitin and proteasome pathways
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • RNA modifications and cancer
  • Calcium signaling and nucleotide metabolism

Frequent co-authors associated with Michael L. Nielsen include:

  • Ivo A. Hendriks
  • Sara C. Buch-Larsen
  • Julien P. Duxin
  • Niels Mailand
  • Ivan Ahel

Consistent publication venues where Nielsen's work appears are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Reports
  • Molecular Cell
  • The EMBO Journal

Representative recent papers include:

  • "ADP-ribosyltransferases, an update on function and nomenclature," 2021, FEBS Journal
  • "Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation," 2020, Cell Reports
  • "The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome," 2021, Nature Communications
  • "Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation," 2020, Nature Communications
  • "Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease," 2021, Molecular Cell

Best Publications

  • Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

    Chuna Ram Choudhary;Chanchal Kumar;Florian Gnad;Michael L Nielsen

  • Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast.

    Lyris M. F. de Godoy;Jesper V. Olsen;Jürgen Cox;Michael L. Nielsen

  • A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Sebastian A. Wagner;Petra Beli;Brian T. Weinert;Michael L. Nielsen

  • A Dual Pressure Linear Ion Trap Orbitrap Instrument with Very High Sequencing Speed

    Jesper Olsen;Jae C Schwartz;Jens Griep-Raming;Michael L. Nielsen

  • Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

    Matthias Altmeyer;Matthias Altmeyer;Kai J. Neelsen;Federico Teloni;Irina Pozdnyakova

  • An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.

    Dorte B. Bekker-Jensen;Christian D. Kelstrup;Tanveer S. Batth;Sara C. Larsen

  • Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

    Celia J. Webby;Alexander Wolf;Natalia Gromak;Mathias Dreger

  • Citrullination regulates pluripotency and histone H1 binding to chromatin

    Maria A Christophorou;Gonçalo Castelo-Branco;Richard P Halley-Stott;Clara Slade Oliveira

  • Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

    Stephanie Jungmichel;Florian Rosenthal;Matthias Altmeyer;Jiri Lukas

  • Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

    Iben Lundgaard;Baoman Li;Lulu Xie;Hongyi Kang

  • Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

    Jannie M.R. Danielsen;Kathrine B. Sylvestersen;Simon Bekker-Jensen;Damian Szklarczyk

  • Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation

    Ivo A Hendriks;David Lyon;Clifford Young;Lars J Jensen

  • Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry.

    Michael L Nielsen;Michiel Vermeulen;Tiziana Bonaldi;Jürgen Cox

  • Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues

    Sebastian A. Wagner;Sebastian A. Wagner;Petra Beli;Brian T. Weinert;Christian Schölz

  • Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer.

    Christian D. Kelstrup;Clifford Young;Richard Lavallee;Michael L. Nielsen

  • Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

    Sara C. Larsen;Kathrine B. Sylvestersen;Andreas Mund;David Lyon

  • Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.

    Lou K. Povlsen;Petra Beli;Sebastian A. Wagner;Sara L. Poulsen

  • De novo peptide sequencing and identification with precision mass spectrometry.

    Ari M. Frank;Mikhail M. Savitski;Michael N. Nielsen;Roman A. Zubarev

  • Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Peter Tessarz;Helena Santos-Rosa;Sam C. Robson;Kathrine B. Sylvestersen

  • ADP-ribosyltransferases, an update on function and nomenclature

    Bernhard Lüscher;Ivan Ahel;Matthias Altmeyer;Alan Ashworth

Frequent Co-Authors

Roman A. Zubarev
Roman A. Zubarev Karolinska Institute
Mikhail M. Savitski
Mikhail M. Savitski European Bioinformatics Institute
Jesper V. Olsen
Jesper V. Olsen University of Copenhagen
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Chunaram Choudhary
Chunaram Choudhary University of Copenhagen
Niels Mailand
Niels Mailand University of Copenhagen
Tony Kouzarides
Tony Kouzarides University of Cambridge
Lars Juhl Jensen
Lars Juhl Jensen University of Copenhagen
Matthias Altmeyer
Matthias Altmeyer University of Zurich
Mathias Uhlén
Mathias Uhlén Royal Institute of Technology

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