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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
17591
World Ranking
9053
National Ranking
4023

Overview

Wenwei Hu is affiliated with Rutgers, The State University of New Jersey in the United States. Their research focuses primarily on Medicine, with a significant body of work in Biochemistry, Genetics, and Molecular Biology.

The scientist's research covers several subfields, including Oncology, Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, and Immunology. Their work spans key topics such as Cancer-related Molecular Pathways, Cancer, Hypoxia, and Metabolism, Cancer Immunotherapy and Biomarkers, RNA modifications and cancer, Gastric Cancer Management and Outcomes, Ferroptosis and cancer prognosis, and Epigenetics and DNA Methylation.

Wenwei Hu's publications have appeared in a range of research venues, with notable frequency in:

  • Cancer Research
  • Nature Communications
  • Journal of Clinical Oncology
  • Cell Death and Disease
  • Journal of Molecular Cell Biology

Recent papers authored or co-authored by Wenwei Hu include:

  • Gain-of-function mutant p53 in cancer progression and therapy, 2020, Journal of Molecular Cell Biology
  • The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway, 2020, International Journal of Molecular Sciences
  • Autophagy promotes mammalian survival by suppressing oxidative stress and p53, 2020, Genes & Development
  • The Interplay Between Tumor Suppressor p53 and Hypoxia Signaling Pathways in Cancer, 2021, Frontiers in Cell and Developmental Biology
  • Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression, 2020, Journal of Clinical Investigation

Frequent collaborators contributing to the scientist's work include:

  • Zhaohui Feng
  • Jianming Wang
  • Cen Zhang
  • Chun-Yuan Chang
  • Lanjing Zhang

Best Publications

  • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.

    Gareth L. Bond;Wenwei Hu;Elisabeth E. Bond;Harlan Robins

  • Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

    Wenwei Hu;Cen Zhang;Rui Wu;Yvonne Sun

  • The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways

    Zhaohui Feng;Wenwei Hu;Elisa de Stanchina;Angelika K. Teresky

  • p53 regulates maternal reproduction through LIF

    Wenwei Hu;Zhaohui Feng;Angelika K. Teresky;Arnold J. Levine;Arnold J. Levine

  • Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair

    Zhaohui Feng;Wenwei Hu;Yu Hu;Moon-shong Tang

  • Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

    Cen Zhang;Meihua Lin;Rui Wu;Xiaowen Wang

  • Tumour-associated mutant p53 drives the Warburg effect.

    Cen Zhang;Juan Liu;Yingjian Liang;Rui Wu

  • A plausible model for the digital response of p53 to DNA damage

    Lan Ma;John Wagner;John Jeremy Rice;Wenwei Hu

  • MDM2 is a Central Node in the p53 Pathway: 12 Years and Counting

    Gareth L. Bond;Wenwei Hu;Arnold J. Levine

  • The Origins and Evolution of the p53 Family of Genes

    Vladimir A. Belyi;Prashanth Ak;Elke Markert;Haijian Wang

  • Negative regulation of tumor suppressor p53 by microRNA miR-504.

    Wenwei Hu;Chang S. Chan;Rui Wu;Cen Zhang

  • The major lipid peroxidation product, trans- 4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

    Wenwei Hu;Zhaohui Feng;Jamie Eveleigh;Ganesh Iyer

  • Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations

    Zhaohui Feng;Wenwei Hu;Angelika K Teresky;Eva Hernando

  • Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy.

    Xuetian Yue;Yuhan Zhao;Yang Xu;Min Zheng

  • Tumor suppressor p53 and its mutants in cancer metabolism.

    Juan Liu;Cen Zhang;Wenwei Hu;Zhaohui Feng

  • Tumor suppressor p53 meets microRNAs

    Zhaohui Feng;Cen Zhang;Rui Wu;Wenwei Hu

  • Tumor suppressor p53 and metabolism

    Juan Liu;Cen Zhang;Wenwei Hu;Zhaohui Feng

  • Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis.

    Zhaohui Feng;Wenwei Hu;Moon Shong Tang

  • A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect.

    Gareth L. Bond;Wenwei Hu;Arnold Levine

  • Gain-of-function mutant p53 in cancer progression and therapy.

    Cen Zhang;Juan Liu;Dandan Xu;Tianliang Zhang

Frequent Co-Authors

Zhaohui Feng
Zhaohui Feng Rutgers, The State University of New Jersey
Arnold J. Levine
Arnold J. Levine Institute for Advanced Study
Bruce G. Haffty
Bruce G. Haffty Rutgers, The State University of New Jersey
Eileen White
Eileen White Rutgers, The State University of New Jersey
Harlan Robins
Harlan Robins Adaptive Biotechnologies (United States)
William N. Rom
William N. Rom New York University
Xin Lu
Xin Lu University of Oxford
Frederick A. Beland
Frederick A. Beland National Center for Toxicological Research
Youli Zu
Youli Zu Houston Methodist
Maureen E. Murphy
Maureen E. Murphy The Wistar Institute

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