D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 48 Citations 9,029 139 World Ranking 14097 National Ranking 1123

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Genetics
  • Gene expression

Simon M. Hughes mainly investigates Cell biology, Skeletal muscle, Myocyte, Myosin and Endocrinology. His work on Astrocyte differentiation as part of general Cell biology research is frequently linked to Oligodendrocyte differentiation, bridging the gap between disciplines. MyoD and Myogenesis are among the areas of Skeletal muscle where the researcher is concentrating his efforts.

His studies in Myocyte integrate themes in fields like Multinucleate and Cytoplasm. His research in Myosin focuses on subjects like Gene isoform, which are connected to Function, Epitope, Antibody and Monoclonal antibody. Simon M. Hughes has researched Endocrinology in several fields, including Basal lamina, Internal medicine, Cell migration and Somite.

His most cited work include:

  • The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover (480 citations)
  • Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones (368 citations)
  • Nanoscale live-cell imaging using hopping probe ion conductance microscopy. (338 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Skeletal muscle, Zebrafish, Myocyte and Myogenesis. His Cell biology study combines topics in areas such as Internal medicine, Somite, Cellular differentiation and Endocrinology. In his study, Cell growth is inextricably linked to Atrophy, which falls within the broad field of Skeletal muscle.

His Zebrafish research includes elements of Vertebrate and Myotome. The study incorporates disciplines such as Muscle tissue, Anatomy, Molecular biology and Multinucleate in addition to Myocyte. His work deals with themes such as Limb bud, Wnt signaling pathway and Transcription factor, which intersect with Myogenesis.

He most often published in these fields:

  • Cell biology (59.13%)
  • Skeletal muscle (31.30%)
  • Zebrafish (30.43%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (59.13%)
  • Zebrafish (30.43%)
  • Skeletal muscle (31.30%)

In recent papers he was focusing on the following fields of study:

Simon M. Hughes mainly focuses on Cell biology, Zebrafish, Skeletal muscle, Myogenesis and MyoD. His research in Cell biology intersects with topics in Transcription factor and Mutant. His research integrates issues of Phenotype, Internal medicine, Epidermal growth factor receptor and Endocrinology in his study of Zebrafish.

His Skeletal muscle research incorporates elements of Stimulus, Signal transduction, Growth factor and Cellular differentiation. His Myogenesis research is within the category of Myocyte. In general MyoD, his work in MYF5 is often linked to Notochord linking many areas of study.

Between 2016 and 2021, his most popular works were:

  • Mef2 and the skeletal muscle differentiation program (48 citations)
  • Myogenin promotes myocyte fusion to balance fibre number and size. (37 citations)
  • Crispr/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function (20 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Genetics
  • Gene expression

His scientific interests lie mostly in Cell biology, Zebrafish, Myogenesis, Transcription factor and MyoD. As a part of the same scientific study, Simon M. Hughes usually deals with the Zebrafish, concentrating on Myotome and frequently concerns with Wnt signaling pathway and Dermomyotome. Myocyte and Skeletal muscle are inherently bound to his Myogenesis studies.

His Myocyte research is mostly focused on the topic Myogenin. The various areas that Simon M. Hughes examines in his Myogenin study include Multinucleate, Stem cell and Developmental biology. Simon M. Hughes has researched Transcription factor in several fields, including Gene expression and Alternative splicing.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover

Stephan Lange;Fengqing Xiang;Andrey Yakovenko;Anna Vihola.
Science (2005)

641 Citations

Nanoscale live-cell imaging using hopping probe ion conductance microscopy.

Pavel Novak;Chao Li;Andrew I Shevchuk;Ruben Stepanyan.
Nature Methods (2009)

477 Citations

Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones

Simon M. Hughes;Jane M. Taylor;Stephen J. Tapscott;Cathy M. Gurley.
Development (1993)

468 Citations

Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog

Chris S. Blagden;Peter D. Currie;Philip W. Ingham;Philip W. Ingham;Simon M. Hughes.
Genes & Development (1997)

417 Citations

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

Simon M. Hughes;Laura E. Lillien;Martin C. Raff;Hermann Rohrer.
Nature (1988)

409 Citations

Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

Laura E. Lillien;Michael Sendtner;Hermann Rohrer;Simon M. Hughes.
Neuron (1988)

301 Citations

Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy.

Andrew S. Brack;Heidi Bildsoe;Simon M. Hughes;Simon M. Hughes.
Journal of Cell Science (2005)

279 Citations

WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons

Olga Krylova;Judit Herreros;Karen E Cleverley;Elisabeth Ehler.
Neuron (2002)

241 Citations

A continuous 4D motion model from multiple respiratory cycles for use in lung radiotherapy

Jamie R. McClelland;Jane M. Blackall;Ségolène Tarte;Adam C. Chandler.
Medical Physics (2006)

240 Citations

Migration of myoblasts across basal lamina during skeletal muscle development.

Simon M. Hughes;Helen M. Blau.
Nature (1990)

237 Citations

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