Simon M. Hughes

Overview

Best Publications

• The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover

  Stephan Lange;Fengqing Xiang;Andrey Yakovenko;Anna Vihola

  671
  Citations

• Nanoscale live-cell imaging using hopping probe ion conductance microscopy.

  Pavel Novak;Chao Li;Andrew I Shevchuk;Ruben Stepanyan

  562
  Citations

• Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones

  Simon M. Hughes;Jane M. Taylor;Stephen J. Tapscott;Cathy M. Gurley

  480
  Citations

• Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog

  Chris S. Blagden;Peter D. Currie;Philip W. Ingham;Philip W. Ingham;Simon M. Hughes

  430
  Citations

• Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

  Simon M. Hughes;Laura E. Lillien;Martin C. Raff;Hermann Rohrer

  413
  Citations

• Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy.

  Andrew S. Brack;Heidi Bildsoe;Simon M. Hughes;Simon M. Hughes

  313
  Citations

• Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

  Laura E. Lillien;Michael Sendtner;Hermann Rohrer;Simon M. Hughes

  301
  Citations

• Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology

  Jean Pierre Droz;Matti Aapro;Lodovico Balducci;Helen Boyle

  256
  Citations

• A continuous 4D motion model from multiple respiratory cycles for use in lung radiotherapy

  Jamie R. McClelland;Jane M. Blackall;Ségolène Tarte;Adam C. Chandler

  247
  Citations

• WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons

  Olga Krylova;Judit Herreros;Karen E Cleverley;Elisabeth Ehler

  245
  Citations

• Migration of myoblasts across basal lamina during skeletal muscle development.

  Simon M. Hughes;Helen M. Blau

  243
  Citations

• Relationship between Membrane Phosphatidylinositol-4,5-Bisphosphate and Receptor-Mediated Inhibition of Native Neuronal M Channels

  Joanna S Winks;Simon Hughes;Alexander K Filippov;Lucine Tatulian

  236
  Citations

• Myogenin Induces a Shift of Enzyme Activity from Glycolytic to Oxidative Metabolism in Muscles of Transgenic Mice

  Simon M. Hughes;Maggie M.-Y. Chi;Oliver H. Lowry;Kristian Gundersen

  233
  Citations

• Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle

  Simon M. Hughes;Mildred Cho;Ilene Karsch-Mizrachi;Marilyn Travis

  233
  Citations

• Muscle fiber pattern is independent of cell lineage in postnatal rodent development.

  Simon M. Hughes;Helen M. Blau

  215
  Citations

• MyoD protein is differentially accumulated in fast and slow skeletal muscle fibres and required for normal fibre type balance in rodents

  Simon M. Hughes;Kyoko Koishi;Michael Rudnicki;Alison M. Maggs

  196
  Citations

• Sequential actions of Pax3 and Pax7 drive xanthophore development in zebrafish neural crest.

  James E.N. Minchin;Simon M. Hughes

  192
  Citations

• Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis.

  Oliver Coutelle;Chris S. Blagden;Richard Hampson;Chandi Halai

  176
  Citations

• Signals and myogenic regulatory factors restrict pax3 and pax7 expression to dermomyotome-like tissue in zebrafish.

  Christina L. Hammond;Yaniv Hinits;Daniel P.S. Osborn;James E.N. Minchin

  175
  Citations

• Mef2 and the skeletal muscle differentiation program

  Michael V. Taylor;Simon M. Hughes

  166
  Citations