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Lars A. Akslen

Lars A. Akslen

D-Index & Metrics

Medicine

D-Index
93
Citations
58426
World Ranking
10651
National Ranking
45

Overview

Lars A. Akslen is affiliated with the University of Bergen in Norway. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on Oncology, Cancer Research, Molecular Biology, Pulmonary and Respiratory Medicine, and Immunology.

Their work covers various main topics, particularly:

  • Breast Cancer Treatment Studies
  • Cancer Cells and Metastasis
  • Angiogenesis and VEGF in Cancer
  • Cancer Genomics and Diagnostics
  • Global Cancer Incidence and Screening
  • Prostate Cancer Treatment and Research
  • AI in cancer detection

Frequent publication venues for Akslen include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Pathology Clinical Research
  • Breast Cancer Research and Treatment
  • Scientific Reports
  • EBioMedicine

Coauthors regularly collaborating with Akslen are:

  • Elisabeth Wik
  • Gøril Knutsvik
  • Cecilie Askeland
  • Ole J. Halvorsen
  • Dimitrios Kleftogiannis

Examples of recent papers include:

  • Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility, 2020, Nature Genetics
  • AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells, 2020, Journal of Thoracic Oncology
  • Exploring the effects of lifestyle on breast cancer risk, age at diagnosis, and survival: the EBBA-Life study, 2020, Breast Cancer Research and Treatment
  • A novel age-related gene expression signature associates with proliferation and disease progression in breast cancer, 2022, British Journal of Cancer
  • Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus, 2022, Frontiers in Cellular and Infection Microbiology

Best Publications

  • Molecular portraits of human breast tumours

    Charles M. Perou;Therese Sørlie;Michael B. Eisen;Matt van de Rijn

  • Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma

    Torsten O. Nielsen;Forrest D. Hsu;Kristin Jensen;Maggie Cheang

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Re: Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer

    William D. Foulkes;Ingunn M. Stefansson;Pierre O. Chappuis;Louis R. Bégin

  • EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

    Ingeborg M. Bachmann;Ole J. Halvorsen;Karin Collett;Ingunn M. Stefansson

  • Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

    Turid Aas;Anne Lise Børresen;Stephanie Geisler;Birgitte Smith-Sørensen

  • Landscape of genomic alterations in cervical carcinomas

    Akinyemi I. Ojesina;Lee Lichtenstein;Samuel S. Freeman;Chandra Sekhar Pedamallu

  • A switch from E-cadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer.

    Karsten Gravdal;Ole J. Halvorsen;Svein A. Haukaas;Lars A. Akslen

  • Role of Angiogenesis in Human Tumor Dormancy: Animal Models of the Angiogenic Switch

    George N. Naumov;Lars A. Akslen;Judah Folkman

  • Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes.

    Emad A. Rakha;Somaia E. Elsheikh;Somaia E. Elsheikh;Muhammed A. Aleskandarany;Muhammed A. Aleskandarany;Hany O. Habashi;Hany O. Habashi

  • Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.

    Christine Gjerdrum;Crina Tiron;Torill Høiby;Ingunn Stefansson

  • A Model of Human Tumor Dormancy: An Angiogenic Switch From the Nonangiogenic Phenotype

    George N. Naumov;Elise Bender;David Zurakowski;Soo-Young Kang

  • Use of immunohistochemical markers can refine prognosis in triple negative breast cancer

    Marc Tischkowitz;Marc Tischkowitz;Jean-Sébastien Brunet;Jean-Sébastien Brunet;Louis R. Bégin;David G. Huntsman

  • The Prognostic Implication of the Basal-Like (Cyclin Ehigh/p27low/p53+/Glomeruloid-Microvascular-Proliferation+) Phenotype of BRCA1-Related Breast Cancer

    William D. Foulkes;Jean-Sébastien Brunet;Ingunn M. Stefansson;Oddbjørn Straume

  • Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer.

    Stephanie Geisler;Per Eystein Lønning;Turid Aas;Hilde Johnsen

  • Drug-sensitive FGFR2 mutations in endometrial carcinoma

    Amit Dutt;Helga B. Salvesen;Tzu-Hsiu Chen;Alex H. Ramos

  • PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma.

    Helga B. Salvesen;Helga B. Salvesen;Nicola MacDonald;Andy Ryan;Ian J. Jacobs

  • Combined Vascular Endothelial Growth Factor Receptor and Epidermal Growth Factor Receptor (EGFR) Blockade Inhibits Tumor Growth in Xenograft Models of EGFR Inhibitor Resistance

    George N. Naumov;Monique B. Nilsson;Tina Cascone;Alexandra Briggs

  • Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer

    Karin Collett;Geir E Eide;Jarle Arnes;Ingunn M Stefansson

  • RESPONSE: Re: Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer

    William D. Foulkes;Lars A. Akslen

Frequent Co-Authors

Helga B. Salvesen
Helga B. Salvesen Haukeland University Hospital
Anders Molven
Anders Molven University of Bergen
William D. Foulkes
William D. Foulkes McGill University
Per Eystein Lønning
Per Eystein Lønning Haukeland University Hospital
Johan R. Lillehaug
Johan R. Lillehaug University of Bergen
Nicholas K. Hayward
Nicholas K. Hayward QIMR Berghofer Medical Research Institute
Anne Lise Børresen-Dale
Anne Lise Børresen-Dale Oslo University Hospital
Susana Puig
Susana Puig University of Barcelona
Rameen Beroukhim
Rameen Beroukhim Harvard University
Matthew Meyerson
Matthew Meyerson Harvard University

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