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Medicine

D-Index
85
Citations
33650
World Ranking
14439
National Ranking
7304

Overview

Louise C. Strong is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on medical and biochemical topics, with significant contributions in oncology and molecular biology. Their work intersects cancer research, particularly in molecular pathways, genetic factors, and diagnostics.

Their recent publications cover topics such as hereditary cancer syndromes, cancer epidemiology, and secondary cancer screening outcomes. Notable papers include:

  • Li-Fraumeni Exploration Consortium Data Coordinating Center: Building an Interactive Web-Based Resource for Collaborative International Cancer Epidemiology Research for a Rare Condition, 2020, Cancer Epidemiology Biomarkers & Prevention
  • A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome, 2020, Genome Research
  • A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Abstract PS8-04: Clinical and pathological characteristics and screening outcome for secondary cancers in breast cancer patients with li-fraumeni syndrome attending the MD anderson li-fraumeni education and early detection program clinic, 2021, Cancer Research
  • Cancer mortality in relatives of desmoid sarcoma patients, 2023, Revista Brasileira de Cancerologia

Their work covers several main fields of study:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields relevant to their research include:

  • Oncology
  • Molecular Biology
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Pathology and Forensic Medicine

Key topics covered in their research are:

  • Cancer-related Molecular Pathways
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Advanced Breast Cancer Therapies
  • BRCA gene mutations in cancer
  • Genetic factors in colorectal cancer
  • Soft tissue tumor case studies

Frequent collaborators in their research include L. Phuong, Jasmina Bojadzieva, Kim E. Nichols, Judy E. Garber, and Constance A. Griffin. These coauthors have contributed to multiple projects, often exploring hereditary cancer syndromes and genomics.

Their findings have been disseminated across various publication venues, notably:

  • UNC Libraries
  • Cancer Epidemiology Biomarkers & Prevention
  • Genome Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research

Best Publications

  • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

    David Malkin;Frederick P. Li;Frederick P. Li;Louise C. Strong;Joseph F. Fraumeni

  • Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

    W. K. Cavenee;W. K. Cavenee;T. P. Dryja;R. A. Phillips;William F Benedict

  • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.

    Gareth L. Bond;Wenwei Hu;Elisabeth E. Bond;Harlan Robins

  • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

    Yuxin Yin;Michael A. Tainsky;Farideh Z. Bischoff;Louise C. Strong

  • Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome

    Gene A. Lang;Tomoo Iwakuma;Young Ah Suh;Geng Liu

  • Mutation and Cancer: A Model for Wilms' Tumor of the Kidney

    Alfred G. Knudson;Alfred G. Knudson;Louise C. Strong

  • Bone sarcomas linked to radiotherapy and chemotherapy in children.

    MA Tucker;GJ D'Angio;Jr Jd Boice;LC Strong

  • Study design and cohort characteristics of the Childhood Cancer Survivor Study: a multi-institutional collaborative project.

    Leslie L. Robison;Ann C. Mertens;John D. Boice;Norman E. Breslow

  • The Childhood Cancer Survivor Study: A National Cancer Institute–Supported Resource for Outcome and Intervention Research

    Leslie L. Robison;Gregory T. Armstrong;John D. Boice;Eric J. Chow

  • Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk.

    T S Frank;S A Manley;O I Olopade;S Cummings

  • Effects of treatment on fertility in long-term survivors of childhood or adolescent cancer.

    Byrne J;Mulvihill Jj;Myers Mh;Connelly Rr

  • Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms.

    David Malkin;Stephen H. Friend;Frederick P. Li;Louise C. Strong

  • Mutation and cancer: neuroblastoma and pheochromocytoma.

    A. G. Knudson;Louise C Strong

  • Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

    Christian P. Kratz;Maria Isabel Achatz;Laurence Brugieres;Thierry Frebourg

  • Characterization of BRCA1 and BRCA2 Mutations in a Large United States Sample

    Sining Chen;Edwin S. Iversen;Tara Friebel;Dianne Finkelstein

  • Cancer Survivorship—Genetic Susceptibility and Second Primary Cancers: Research Strategies and Recommendations

    Lois B. Travis;Charles S. Rabkin;Linda Morris Brown;James M. Allan

  • Familial renal cell carcinoma with a 3 ; 11 chromosome translocation limited to tumor cells

    S. Pathak;Louise C Strong;R. E. Ferrell;A. Trindade

  • Spontaneous Abnormalities in Normal Fibroblasts from Patients with Li-Fraumeni Cancer Syndrome: Aneuploidy and Immortalization

    Farideh Z. Bischoff;Sun O. Yim;Sen Pathak;Grace Grant

  • Genetic Disease in Offspring of Long-Term Survivors of Childhood and Adolescent Cancer

    Julianne Byrne;Julianne Byrne;Sonja A. Rasmussen;Sandra C. Steinhorn;Roger R. Connelly

  • Germline p53 Mutations in a Cohort with Childhood Sarcoma: Sex Differences in Cancer Risk

    Shih Jen Hwang;Guillermina Lozano;Christopher I. Amos;Louise C. Strong

Frequent Co-Authors

Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Vicki Huff
Vicki Huff The University of Texas MD Anderson Cancer Center
Leslie L. Robison
Leslie L. Robison St. Jude Children's Research Hospital
Grady F. Saunders
Grady F. Saunders The University of Texas MD Anderson Cancer Center
Judy Garber
Judy Garber Harvard University
Smita Bhatia
Smita Bhatia University of Alabama at Birmingham
Guillermina Lozano
Guillermina Lozano The University of Texas MD Anderson Cancer Center
Sharon A. Savage
Sharon A. Savage National Institutes of Health
Banu Arun
Banu Arun The University of Texas MD Anderson Cancer Center
Frederick P. Li
Frederick P. Li Harvard University

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