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Biology and Biochemistry

D-Index
84
Citations
41049
World Ranking
3237
National Ranking
1639

Overview

Thomas J. Schall is affiliated with ChemoCentryx in the United States. Their research primarily spans the field of Medicine, with a significant focus on subfields including Oncology, Immunology, Genetics, Nephrology, and Pulmonary and Respiratory Medicine.

The scientist has contributed to several main topics within medical research, notably:

  • Vasculitis and related conditions
  • Renal Diseases and Glomerulopathies
  • Cancer Immunotherapy and Biomarkers
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Cell Adhesion Molecules Research
  • Chemokine receptors and signaling
  • Complement system in diseases

Thomas J. Schall's recent publications include:

  • "Avacopan for the Treatment of ANCA-Associated Vasculitis," 2021, New England Journal of Medicine
  • "Cancer associated fibroblast FAK regulates malignant cell metabolism," 2020, Nature Communications
  • "Adjunctive Treatment With Avacopan, an Oral C5a Receptor Inhibitor, in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis," 2020, ACR Open Rheumatology
  • "Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells," 2020, Cell
  • "Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias," 2022, Science Advances

Frequent collaborators in their research include Linda Ertl, Penglie Zhang, Kathleen M. Sullivan, Israel Charo, and Pirow Bekker.

Their work has been published repeatedly in several scientific journals, including:

  • Nephrology Dialysis Transplantation
  • Journal of the American Society of Nephrology
  • Kidney International Reports
  • Chemie Ingenieur Technik
  • Journal of Investigative Dermatology

Best Publications

  • Identification of a major co-receptor for primary isolates of HIV-1

    H Deng;R Liu;W Ellmeier;S Choe

  • A new class of membrane-bound chemokine with a CX3C motif

    J F Bazan;K B Bacon;G Hardiman;W Wang

  • Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

    Toshio Imai;Kunio Hieshima;Christopher Haskell;Masataka Baba

  • Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES.

    Thomas J. Schall;Kevin Bacon;Karen J. Toy;David V. Goeddel

  • Molecular cloning and expression of a receptor for human tumor necrosis factor.

    Thomas J. Schall;Martyn Lewis;Kerry J. Koller;Angela Lee

  • A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

    Jennifer M. Burns;Bretton C. Summers;Yu Wang;Anita Melikian

  • Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

    Kuldeep Neote;David DiGregorio;John Y. Mak;Richard Horuk

  • Biology of the rantes/sis cytokine family

    Thomas J. Schall

  • Chemokines, leukocyte trafficking, and inflammation.

    Thomas J. Schall;Kevin B. Bacon

  • Chemokine receptors: gateways to inflammation and infection.

    Brett A. Premack;Thomas J. Schall

  • Lymphotactin: a cytokine that represents a new class of chemokine

    Gregory S. Kelner;Jacqueline Kennedy;Kevin B. Bacon;Sarah Kleyensteuber

  • RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes.

    Antal Rot;Martin Krieger;Thomas Brunner;Stephan C. Bischoff

  • CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature

    Zhenhua Miao;Kathryn E. Luker;Bretton C. Summers;Rob Berahovich

  • Human macrophage inflammatory protein alpha (MIP-1 alpha) and MIP-1 beta chemokines attract distinct populations of lymphocytes.

    Thomas J. Schall;Kevin Bacon;Richard D. R. Camp;James W. Kaspari

  • A human T cell-specific molecule is a member of a new gene family.

    Thomas J. Schall;Jan Jongstra;Bradley J. Dyer;Jeffrey L Jorgensen

  • Activation of dual T cell signaling pathways by the chemokine RANTES

    Kevin B. Bacon;Brett A. Premack;Phyllis Gardner;Thomas J. Schall

  • Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis.

    David R W Jayne;Annette N Bruchfeld;Lorraine Harper;Matthias Schaier

  • Cytomegalovirus encodes a potent alpha chemokine.

    Mark E. T. Penfold;Daniel J. Dairaghi;Gregory M. Duke;Noah Saederup

  • Chemokine/chemokine receptor nomenclature

    K. Bacon;M. Baggiolini;Hal Broxmeyer;R. Horuk

  • CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.

    David R. Greaves;Wei Wang;Daniel J. Dairaghi;Marie Caroline Dieu

Frequent Co-Authors

Israel F. Charo
Israel F. Charo University of California, San Francisco
David Jayne
David Jayne University of Cambridge
Richard Horuk
Richard Horuk University of California, Davis
Albert Zlotnik
Albert Zlotnik University of California, Irvine
Mårten Segelmark
Mårten Segelmark Lund University
Michel Jadoul
Michel Jadoul Université Catholique de Louvain
Maureen Howard
Maureen Howard Stanford University
David V. Goeddel
David V. Goeddel The Colum Group
Shaun R. McColl
Shaun R. McColl University of Adelaide
Alan M. Krensky
Alan M. Krensky Northwestern University

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