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Amanda E. I. Proudfoot

Amanda E. I. Proudfoot

D-Index & Metrics

Immunology

D-Index
98
Citations
34023
World Ranking
789
National Ranking
51

Overview

Amanda E. I. Proudfoot was affiliated with Merck (Germany) in Germany. Their research primarily focused on the biology and pharmacology of chemokine receptors, which are critical in cell signaling pathways related to immune response and cancer. Throughout their career, they contributed to multiple publications in a specialized field of Medicine, particularly within Oncology and Immunology subfields.

Their recent publications consistently appeared in the venue IUPHAR/BPS Guide to Pharmacology CITE, marking a clear focus on high-quality pharmacological databases and reviews related to chemokine receptors. The following papers document their continued involvement over several years:

  • Chemokine receptors (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database, 2020, IUPHAR/BPS Guide to Pharmacology CITE
  • Chemokine receptors in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Chemokine receptors in GtoPdb v.2025.1, 2025, IUPHAR/BPS Guide to Pharmacology CITE
  • Chemokine receptors in GtoPdb v.2025.3, 2025, IUPHAR/BPS Guide to Pharmacology CITE

Their scholarly work concentrated on several main topics:

  • Chemokine receptors and signaling
  • Immune cells in cancer
  • Cytokine Signaling Pathways and Interactions

Throughout their career, Amanda E. I. Proudfoot collaborated frequently with a group of coauthors who appeared repeatedly in their publications:

  • Françoise Bachelerie
  • Adit Ben-Baruch
  • Amanda M. Burkhardt
  • Israel Charo
  • Christophe Combadière

Their contributions advanced the understanding of chemokine receptor biology within the contexts of immune modulation and cancer. By participating in the curation and updating of pharmacological databases, they provided reference points widely used within the scientific community studying receptor signaling.

Best Publications

  • Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

    Amanda E. I. Proudfoot;Tracy M. Handel;Zoë Johnson;Elaine K. Lau

  • International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors

    Francoise Bachelerie;Adit Ben-Baruch;Amanda M. Burkhardt;Christophe Combadiere

  • Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

    Graham Simmons;Paul R. Clapham;Laurent Picard;Robin E. Offord

  • Lymph-Borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex

    J. Elizabeth Gretz;Christopher C. Norbury;Arthur O. Anderson;Amanda E.I. Proudfoot

  • Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6Chi and Ly6Clo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

    Christophe Combadière;Stéphane Potteaux;Mathieu Rodero;Tabassome Simon

  • RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis.

    Clare M. Lloyd;Andrew W. Minto;Martin E. Dorf;Amanda Proudfoot

  • Chemokine receptors: multifaceted therapeutic targets

    Unknown

  • HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

    Milena Schiraldi;Angela Raucci;Laura Martínez Muñoz;Elsa Livoti

  • RANTES Deposition by Platelets Triggers Monocyte Arrest on Inflamed and Atherosclerotic Endothelium

    Philipp von Hundelshausen;Philipp von Hundelshausen;Philipp von Hundelshausen;Kim S. C. Weber;Kim S. C. Weber;Kim S. C. Weber;Yuqing Huo;Yuqing Huo;Yuqing Huo;Amanda E. I. Proudfoot;Amanda E. I. Proudfoot;Amanda E. I. Proudfoot

  • Regulation of protein function by glycosaminoglycans- : As exemplified by chemokines

    T M Handel;Z Johnson;S E Crown;E K Lau

  • Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses.

    Gabriele S. V. Kuschert;Florence Coulin;Christine A. Power;Amanda E. I. Proudfoot

  • The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness

    Jose-Angel Gonzalo;Clare M. Lloyd;Danyi Wen;Juan P. Albar

  • Glycosaminoglycans Mediate Cell Surface Oligomerization of Chemokines

    Arlene J. Hoogewerf;Gabriele S. V. Kuschert;Amanda E. I. Proudfoot;Frederic Borlat

  • CC Chemokine Receptor (CCR)4 and the CCR10 Ligand Cutaneous T Cell–attracting Chemokine (CTACK) in Lymphocyte Trafficking to Inflamed Skin

    Yvonne Reiss;Amanda E. Proudfoot;Christine A. Power;James J. Campbell

  • Expression and Characterization of the Chemokine Receptors CCR2 and CCR5 in Mice

    Matthias Mack;Josef Cihak;Christopher Simonis;Bruno Luckow

  • Extension of Recombinant Human RANTES by the Retention of the Initiating Methionine Produces a Potent Antagonist

    Amanda E.I. Proudfoot;Christine A. Power;Arlene J. Hoogewerf;Marc-Olivier Montjovent

  • Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

    Matthias Mack;Bruno Luckow;Peter J. Nelson;Josef Cihak

  • Antagonism of RANTES Receptors Reduces Atherosclerotic Plaque Formation in Mice

    Niels R. Veillard;Brenda Kwak;Graziano Pelli;Flore Mulhaupt

  • Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

    Philipp von Hundelshausen;Rory R. Koenen;Markus Sack;Sebastian F. Mause

  • Overcoming hurdles in developing successful drugs targeting chemokine receptors

    Unknown

  • Molecular Cloning and Functional Expression of a Novel CC Chemokine Receptor cDNA from a Human Basophilic Cell Line

    Christine A. Power;Alexandra Meyer;Karin Nemeth;Kevin B. Bacon

  • HIV-1 Tat protein mimicry of chemokines

    Adriana Albini;Silvano Ferrini;Roberto Benelli;Sabrina Sforzini

  • Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3α from Lung Dendritic Cells

    Christine A. Power;Dennis J. Church;Alexandra Meyer;Sami Alouani

Frequent Co-Authors

Christine A. Power
Christine A. Power Merck Serono (Italy)
Timothy N. C. Wells
Timothy N. C. Wells Cardiff University
Paul R. Clapham
Paul R. Clapham University of Massachusetts Chan Medical School
Tracy M. Handel
Tracy M. Handel University of Montana
Christian Weber
Christian Weber Ludwig-Maximilians-Universität München
Matthias Mack
Matthias Mack University of Regensburg
Alain Bernard
Alain Bernard Grenoble Alpes University
Manuel C. Peitsch
Manuel C. Peitsch Philip Morris International (United States)
Mauro M. Teixeira
Mauro M. Teixeira Universidade Federal de Minas Gerais

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Best Scientists Citing Amanda E. I. Proudfoot