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Immunology

D-Index
72
Citations
25900
World Ranking
2176
National Ranking
1056

Overview

Paul R. Clapham is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple fields, including Immunology and Microbiology and Medicine, with a particular focus on several specialized subfields such as Virology, Industrial and Manufacturing Engineering, Molecular Biology, Radiology, Nuclear Medicine and Imaging, and Strategy and Management.

Their recent publications reflect a diverse range of topics, highlighting their involvement in both biomedical research and sustainable industrial practices. Notably, their works include:

  • Precursor considerations for new circular economy business models, 2022, published in IOP Conference Series Earth and Environmental Science
  • Implications of the 375W mutation for HIV-1 tropism and vaccine development, 2022, published in bioRxiv (Cold Spring Harbor Laboratory)
  • Implications of the 375W mutation for HIV-1 tropism and vaccine development, 2024, published in Journal of Virology

These publications demonstrate their active engagement with the study of HIV research and treatment, as well as vaccines and immunoinformatics approaches. Additionally, Paul R. Clapham has contributed to research on sustainable supply chain management, recycling and waste management techniques, and sustainable industrial ecology.

Their frequent co-authors include:

  • Odette Verdejo-Torres
  • Tania Vargas-Pavia
  • Syeda Urooj Fatima
  • Maria José Duenas-Decamp
  • Usha Iyer-Raniga

Their work has been disseminated through various publication venues such as bioRxiv (Cold Spring Harbor Laboratory), IOP Conference Series Earth and Environmental Science, and the Journal of Virology.

Paul R. Clapham's main topics of research cover a broad range of scientific and technical areas, including:

  • HIV Research and Treatment
  • Vaccines and Immunoinformatics Approaches
  • Monoclonal and Polyclonal Antibodies Research
  • Sustainable Supply Chain Management
  • Recycling and Waste Management Techniques
  • Sustainable Industrial Ecology
  • Immune Cell Function and Interaction

This combination of expertise situates Paul R. Clapham at the intersection of biomedical science and sustainable industrial practices, providing an interdisciplinary perspective on both health and environmental challenges through their ongoing academic contributions.

Best Publications

  • The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

    Angus G. Dalgleish;Peter C. L. Beverley;Paul R. Clapham;Dorothy H. Crawford

  • The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain.

    Paul Jay Maddon;Angus G. Dalgleish;J.Steven McDougal;Paul R. Clapham

  • Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

    Graham Simmons;Paul R. Clapham;Laurent Picard;Robin E. Offord

  • CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

    Michael J Endres;Paul R Clapham;Mark Marsh;Ména Ahuja

  • Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients.

    Robin A. Weiss;Paul R. Clapham;Rachanee Cheingsong-Popov;Angus G. Dalgleish

  • A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus

    Thomas N. Kledal;Mette M. Rosenkilde;Florence Coulin;Graham Simmons

  • Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

    Matthias Mack;Bruno Luckow;Peter J. Nelson;Josef Cihak

  • Identification of the Residues in Human CD4 Critical for the Binding of HIV

    J Arthos;K C Deen;M A Chaikin;J A Fornwald

  • Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells

    Paul R. Clapham;Jonathan N. Weber;Denise Whitby;Kenneth McIntosh;Kenneth McIntosh

  • Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry.

    G Simmons;D Wilkinson;J D Reeves;M T Dittmar

  • Cell surface receptors, virus entry and tropism of primate lentiviruses.

    Paul R. Clapham;Áine McKnight

  • Variable and conserved neutralization antigens of human immunodeficiency virus

    Robin A. Weiss;Paul R. Clapham;Jonathan N. Weber;Angus G. Dalgleish

  • Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by Simian immunodeficiency virus.

    Paul R. Clapham;Dominique Blanc;Robin A. Weiss

  • HIV-1 receptors and cell tropism.

    Paul R Clapham;Áine McKnight

  • The BBXB Motif of RANTES Is the Principal Site for Heparin Binding and Controls Receptor Selectivity

    Amanda E.I. Proudfoot;Sarah Fritchley;Frédéric Borlat;Jeffrey P. Shaw

  • HIV infection does not require endocytosis of its receptor, CD4.

    Paul Jay Maddon;J. Steven McDougal;Paul R. Clapham;Angus G. Dalgleish

  • The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion?

    Gary J. Clements;Molly J. Price-Jones;Paul E. Stephens;Christopher Sutton

  • KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells

    Johnny T. Stine;Christi Wood;Mark Hill;Angela Epp

  • Human T‐cell leukemia virus type I: Induction of syncytia and inhibition by patients' sera

    Károly Nagy;Paul Clapham;Rachanee Cheingsong-Popov;Robin A. Weiss

  • Biological Analysis of Human Immunodeficiency Virus Type 1 R5 Envelopes Amplified from Brain and Lymph Node Tissues of AIDS Patients with Neuropathology Reveals Two Distinct Tropism Phenotypes and Identifies Envelopes in the Brain That Confer an Enhanced Tropism and Fusigenicity for Macrophages

    Paul J. Peters;Jayanta Bhattacharya;Samantha Hibbitts;Matthias T. Dittmar

Frequent Co-Authors

Áine McKnight
Áine McKnight Queen Mary University of London
Robin A. Weiss
Robin A. Weiss University College London
Amanda E. I. Proudfoot
Amanda E. I. Proudfoot Merck (Germany)
Katherine Luzuriaga
Katherine Luzuriaga University of Massachusetts Chan Medical School
Shan Lu
Shan Lu University of Massachusetts Chan Medical School
Mark Marsh
Mark Marsh University College London
Angus G. Dalgleish
Angus G. Dalgleish St George's, University of London
Christine A. Power
Christine A. Power Merck Serono (Italy)
Richard Axel
Richard Axel Columbia University
Peter Simmonds
Peter Simmonds University of Oxford

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