World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
111
Citations
43182
World Ranking
478
National Ranking
25

Medicine

D-Index
111
Citations
43258
World Ranking
5351
National Ranking
296

Overview

Matthias Mack is affiliated with the University of Regensburg in Germany. Their primary fields of study encompass Medicine and Immunology and Microbiology, focusing extensively on subfields such as Immunology, Infectious Diseases, Oncology, Epidemiology, and Surgery.

Their research concentrates on topics including:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Immune Response and Inflammation
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Immunotherapy and Immune Responses
  • Neonatal Respiratory Health Research

Recent research papers authored or co-authored by Matthias Mack include:

  • "Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection" (2021, Cell)
  • "Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations" (2021, Cancer Cell)
  • "Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts" (2021, Journal of Clinical Investigation)
  • "Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection" (2020, Nature Immunology)
  • "Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy" (2021, Immunity)

Frequent co-authors in their publications include:

  • Michael Diamond
  • Kerstin Renner
  • Simone Buchtler
  • Emma S. Winkler
  • André Gessner

Matthias Mack has published regularly in prominent venues, with notable counts in:

  • bioRxiv (Cold Spring Harbor Laboratory) - 15 publications
  • Frontiers in Immunology - 6 publications
  • The Journal of Immunology - 6 publications
  • Nature Immunology - 5 publications
  • Nature Communications - 5 publications

Best Publications

  • LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

    Almut Brand;Katrin Singer;Gudrun E. Koehl;Marlene Kolitzus

  • Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

    Frank Tacke;David Alvarez;Theodore J. Kaplan;Claudia Jakubzick

  • Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

    Rudragouda Channappanavar;Anthony R. Fehr;Rahul Vijay;Matthias Mack

  • Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

    Chia-Lin Tsou;Wendy Peters;Yue Si;Sarah Slaymaker

  • Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

    Kiavash Movahedi;Damya Laoui;Conny Gysemans;Martijn Baeten

  • Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

    Alexander Mildner;Hauke Schmidt;Mirko Nitsche;Doron Merkler

  • Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection.

    Rudragouda Channappanavar;Craig Fett;Matthias Mack;Patrick P. Ten Eyck

  • Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice.

    Ravid Shechter;Anat London;Chen Varol;Catarina Raposo

  • Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells.

    Ehud Zigmond;Chen Varol;Julia Farache;Elinor Elmaliah

  • Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection.

    Matthias Mack;Andrea Kleinschmidt;Hilke Brühl;Christiane Klier

  • A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity

    Matthias Mack;Gert Riethmuller;Peter Kufer

  • Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.

    Julia Bruttger;Khalad Karram;Simone Wörtge;Tommy Regen

  • Mechanosensation of Cyclical Force by PIEZO1 is Essential for Innate Immunity

    Angel G. Solis;Piotr Bielecki;Holly R. Steach;Lokesh Sharma

  • IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

    Rudragouda Channappanavar;Anthony R. Fehr;Jian Zheng;Christine Wohlford-Lenane

  • Expression and Characterization of the Chemokine Receptors CCR2 and CCR5 in Mice

    Matthias Mack;Josef Cihak;Christopher Simonis;Bruno Luckow

  • Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

    Kamran Ghoreschi;Peter Thomas;Susanne Breit;Martin Dugas

  • Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis.

    Sebastiaan De Schepper;Simon Verheijden;Javier Aguilera-Lizarraga;Maria Francesca Viola

  • Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

    Matthias Mack;Bruno Luckow;Peter J. Nelson;Josef Cihak

  • Inflammation and fibrosis.

    Matthias Mack

  • Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

    Calum C. Bain;Catherine A. Hawley;Hannah Garner;Charlotte L. Scott

  • Differential chemokine receptor expression and function in human monocyte subpopulations.

    C Weber;K U Belge;P von Hundelshausen;G Draude

  • CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

    Alexander Mildner;Matthias Mack;Hauke Schmidt;Wolfgang Brück

Frequent Co-Authors

Detlef Schlöndorff
Detlef Schlöndorff Icahn School of Medicine at Mount Sinai
Marco Prinz
Marco Prinz University of Freiburg
Steffen Jung
Steffen Jung Weizmann Institute of Science
Amanda E. I. Proudfoot
Amanda E. I. Proudfoot Merck (Germany)
Werner Seeger
Werner Seeger University of Giessen
Hans-Joachim Anders
Hans-Joachim Anders Ludwig-Maximilians-Universität München
William A. Kuziel
William A. Kuziel The University of Texas at Austin
David E. Briles
David E. Briles University of Alabama at Birmingham
Nico van Rooijen
Nico van Rooijen Vrije Universiteit Amsterdam
James C. Paton
James C. Paton University of Adelaide

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in expanding their expertise within healthcare, particularly in immunology, exploring related online degrees can open diverse career pathways. Many professionals choose to transition or advance their roles by enrolling in specialized programs tailored to their unique needs.

Nurses aspiring to elevate their practice can benefit from an fnp to acnp bridge program online, which facilitates the transition from Family Nurse Practitioner roles to Acute Care Nurse Practitioner positions with flexible, remote learning options.

For those seeking to fast-track their nursing careers, accelerated np programs provide a fast-paced curriculum designed to help students earn Nurse Practitioner credentials efficiently while maintaining quality education standards.

If you’re starting without a nursing background, online bsn programs for non nurses offer accessible pathways into the nursing profession, enabling learners to gain foundational skills and credentials remotely.

Additionally, for students seeking less competitive entry options, easiest accelerated nursing programs to get into can ease the admission process while providing comprehensive nursing education to prepare for a variety of healthcare roles, including those intersecting with immunology.

Best Scientists Citing Matthias Mack

Trending Scientists

Recently Published Articles