World's Best Scientists 2026 revealed!
Lucienne Chatenoud

Lucienne Chatenoud

D-Index & Metrics

Medicine

D-Index
77
Citations
22907
World Ranking
18388
National Ranking
610

Overview

Lucienne Chatenoud is affiliated with Inserm in France and focuses research efforts primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several interconnected subfields including Genetics, Infectious Diseases, Immunology, Oncology, and Endocrinology, Diabetes and Metabolism.

The research topics covered by Chatenoud include:

  • Diabetes and associated disorders
  • SARS-CoV-2 and COVID-19 Research
  • Diabetes Management and Research
  • Pancreatic function and diabetes
  • COVID-19 Clinical Research Studies
  • Immunodeficiency and Autoimmune Disorders
  • CAR-T cell therapy research

Chatenoud's recent publications reflect a focus on immunological responses, infectious diseases, and diabetes. Notable papers include:

  • "Convalescent plasma therapy for B-cell-depleted patients with protracted COVID-19" (2020), published in Blood
  • "Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling" (2020), published in The Journal of Experimental Medicine
  • "Teplizumab and β-Cell Function in Newly Diagnosed Type 1 Diabetes" (2023), published in New England Journal of Medicine
  • "Poor Anti-SARS-CoV-2 Humoral and T-cell Responses After 2 Injections of mRNA Vaccine in Kidney Transplant Recipients Treated With Belatacept" (2021), published in Transplantation
  • "Anti-CD38 therapy impairs SARS-CoV-2 vaccine response against alpha and delta variants in patients with multiple myeloma" (2021), published in Blood

The scientist collaborates frequently with several coauthors, including:

  • Amani Ouedrani
  • Isabelle Staropoli
  • Olivier Schwartz
  • Kevan C. Herold
  • Olivier Hermine

Chatenoud publishes regularly in prominent scientific venues. Frequent publication outlets include:

  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • La Revue de Médecine Interne
  • Diabetologie und Stoffwechsel
  • The Journal of Experimental Medicine

The scientist has also contributed to book publications. One example is the volume entitled "Insights in Immunological Tolerance and Regulation: 2022" published by Frontiers Media in 2023.

Best Publications

  • Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes.

    Bart Keymeulen;Evy Vandemeulebroucke;Anette G. Ziegler;Chantal Mathieu

  • Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

    Lucienne Chatenoud;Eric Thervet;Jacqueline Primo;Jean-Francois Bach

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.

    Mériam Belghith;Jeffrey A Bluestone;Samia Barriot;Jérôme Mégret

  • CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice.

    L Chatenoud;J Primo;J F Bach

  • CD3-specific antibodies: a portal to the treatment of autoimmunity

    Lucienne Chatenoud;Jeffrey A. Bluestone

  • Efficacy and safety of rituximab in B-cell post-transplantation lymphoproliferative disorders: results of a prospective multicenter phase 2 study

    Sylvain Choquet;Veronique Leblond;Raoul Herbrecht;Gérard Socié

  • IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

    Yenkel Grinberg-Bleyer;Audrey Baeyens;Sylvaine You;Rima Elhage

  • CD3-specific antibody-induced active tolerance: from bench to bedside

    Lucienne Chatenoud

  • Suppressor T cells--they're back and critical for regulation of autoimmunity!

    Lucienne Chatenoud;Benoît Salomon;Jeffrey A. Bluestone

  • In vivo cell activation following OKT3 administration. Systemic cytokine release and modulation by corticosteroids.

    Lucienne Chatenoud;Christiane Ferran;Christophe Legendre;Isabelle Thouard

  • Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.

    B Keymeulen;M Walter;Chantal Mathieu;L Kaufman

  • Tolerance to Islet Autoantigens in Type 1 Diabetes

    Jean-François Bach;Lucienne Chatenoud

  • Systemic reaction to the anti-T-cell monoclonal antibody OKT3 in relation to serum levels of tumor necrosis factor and interferon-gamma [corrected].

    L Chatenoud;C Ferran;A Reuter;C Legendre

  • Cytokine‐related syndrome following injection of anti‐CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation

    Christiane Ferran;Kathleen Sheehan;Michel Dy;Robert Schreiber

  • Convalescent plasma therapy for B-cell-depleted patients with protracted COVID-19.

    Thomas Hueso;Thomas Hueso;Cécile Pouderoux;Hélène Péré;Anne Lise Beaumont

  • The generation of a humanized, non-mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties.

    Sarah Bolt;Edward Routledge;Irene Lloyd;Lucienne Chatenoud

  • Autoimmune Diabetes Onset Results From Qualitative Rather Than Quantitative Age-Dependent Changes in Pathogenic T-Cells

    Sylvaine You;Mériam Belghith;Stephen Cobbold;Marie-Alexandra Alyanakian

  • Deficit of suppressor T cells in active multiple sclerosis.

    Marie-Anne Bach;Elizabeth Tournier;Francoise Phan-Dinh-Tuy;Lucienne Chatenoud

  • Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

    James A. Hutchinson;James A. Hutchinson;Paloma Riquelme;Paloma Riquelme;Birgit Sawitzki;Birgit Sawitzki;Stefan Tomiuk;Stefan Tomiuk

  • Restriction of the human in vivo immune response against the mouse monoclonal antibody OKT3.

    L Chatenoud;M F Baudrihaye;N Chkoff;H Kreis

Frequent Co-Authors

Jean-François Bach
Jean-François Bach Grenoble Alpes University
Henri Kreis
Henri Kreis Necker-Enfants Malades Hospital
Jeffrey A. Bluestone
Jeffrey A. Bluestone University of California, San Francisco
Herman Waldmann
Herman Waldmann University of Oxford
Laure-Hélène Noël
Laure-Hélène Noël Necker-Enfants Malades Hospital
Michel Dy
Michel Dy Université Paris Cité
Philippe Menasché
Philippe Menasché Université Paris Cité
Michel Pucéat
Michel Pucéat Aix-Marseille University
Gideon Goldstein
Gideon Goldstein Memorial Sloan Kettering Cancer Center

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