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Klára Hilscherová

Klára Hilscherová

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Environmental Sciences
Czechia
2026

D-Index & Metrics

Environmental Sciences

D-Index
63
Citations
11869
World Ranking
2524
National Ranking
5

Research.com Recognitions

  • 2026 - Research.com Environmental Sciences in Czechia Leader Award
  • 2025 - Research.com Environmental Sciences in Czechia Leader Award

Overview

Klára Hilscherová is affiliated with Masaryk University in the Czech Republic and has a substantial research portfolio in environmental science, with significant contributions to biochemistry, genetics, and molecular biology. Their work addresses various topics related to environmental toxicology, health impacts, and molecular-level biological processes.

The scientist's research encompasses several closely studied topics, including:

  • Effects and risks of endocrine disrupting chemicals
  • Toxic organic pollutants impact
  • Aquatic ecosystems and phytoplankton dynamics
  • Pharmaceutical and antibiotic environmental impacts
  • Retinoids in leukemia and cellular processes
  • Environmental toxicology and ecotoxicology
  • Air quality and health impacts

Key fields of study in their research include environmental science, supported by 62 publications, and biochemistry, genetics, and molecular biology, represented by 26 publications. Subfields prominently featured are health, toxicology, and mutagenesis; molecular biology; environmental chemistry; pollution; and endocrinology, diabetes, and metabolism.

Hilscherová frequently publishes in several scientific venues, with repeated contributions in Toxicology Letters, Journal of Hazardous Materials, Aquatic Toxicology, Environment International, and Archives of Toxicology.

Significant recent publications by Hilscherová include:

  • Application of AOPs to assist regulatory assessment of chemical risks - Case studies, needs and recommendations (2022), Environmental Research
  • Toxic potentials of particulate and gaseous air pollutant mixtures and the role of PAHs and their derivatives (2020), Environment International
  • Molecular nanoinformatics approach assessing the biocompatibility of biogenic silver nanoparticles with channelized intrinsic steatosis and apoptosis (2021), Green Chemistry
  • ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters (2020), International Journal of Molecular Sciences
  • Cytotoxic and Genotoxic Effects of Cyanobacterial and Algal Extracts-Microcystin and Retinoic Acid Content (2021), Toxins

Among the scientist's frequent collaborators are Marie Smutná, Jiří Novák, Zuzana Toušová, Branislav Vrana, and Roman Grabic, indicating a network of ongoing research partnerships.

Best Publications

  • Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays

    Beate I. Escher;Mayumi Allinson;Mayumi Allinson;Rolf Altenburger;Peter A. Bain

  • Effect-directed analysis supporting monitoring of aquatic environments - An in-depth overview

    Werner Brack;Selim Ait-Aissa;Robert M. Burgess;Wibke Busch

  • Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources.

    Werner Brack;Werner Brack;Valeria Dulio;Marlene Ågerstrand;Ian Allan

  • Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management.

    Rolf Altenburger;Selim Ait-Aissa;Philipp Antczak;Thomas Backhaus

  • Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive.

    Beate I. Escher;Selim Aїt-Aїssa;Peter A. Behnisch;Werner Brack;Werner Brack

  • Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures

    Rolf Altenburger;Rolf Altenburger;Werner Brack;Werner Brack;Robert M. Burgess;Wibke Busch

  • Environmental xenobiotics and nuclear receptors--interactions, effects and in vitro assessment.

    Jaroslav Janošek;Klára Hilscherová;Luděk Bláha;Ivan Holoubek

  • Effect-based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect-based methods for diagnosis and monitoring of water quality

    Werner Brack;Selim Ait Aissa;Thomas Backhaus;Valeria Dulio

  • Impact of untreated wastewater on a major European river evaluated with a combination of in vitro bioassays and chemical analysis.

    Maria Konig;Beate I. Escher;Peta A. Neale;Martin Krauss

  • The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management.

    Werner Brack;Rolf Altenburger;Gerrit Schüürmann;Martin Krauss

  • Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples

    Klara Hilscherova;Miroslav Machala;Kurunthachalam Kannan;Alan L. Blankenship

  • Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their Contribution to effects in surface water

    Peta A. Neale;Rolf Altenburger;Selim Aït-Aïssa;François Brion

  • Linking in Vitro Effects and Detected Organic Micropollutants in Surface Water Using Mixture-Toxicity Modeling

    Peta A. Neale;Peta A. Neale;Selim Ait-Aissa;Werner Brack;Werner Brack;Nicolas Creusot

  • Assessment of the Effects of Chemicals on the Expression of Ten Steroidogenic Genes in the H295R Cell Line Using Real-Time PCR

    Klara Hilscherova;Paul D. Jones;Tannia Gracia;John L. Newsted

  • What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe

    Barbora Jarošová;Luděk Bláha;John P. Giesy;Klára Hilscherová

  • Cell bioassays for detection of aryl hydrocarbon (AhR) and estrogen receptor (ER) mediated activity in environmental samples.

    J.P. Giesy;K. Hilscherova;P.D. Jones;K. Kannan

  • Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams.

    Peta A. Neale;Nicole A. Munz;Selim Aїt-Aїssa;Rolf Altenburger

  • Ecotoxicity and genotoxicity assessment of cytostatic pharmaceuticals.

    Radka Zounková;Pavel Odráska;Lenka Dolezalová;Klára Hilscherová;Klára Hilscherová

  • Polychlorinated dibenzo-p-dioxin and dibenzofuran concentration profiles in sediments and flood-plain soils of the Tittabawassee River, Michigan.

    Klara Hilscherova;Kurunthachalam Kannan;Haruhiko Nakata;Nobuyasu Hanari

  • Toxic effects and oxidative stress in higher plants exposed to polycyclic aromatic hydrocarbons and their N-heterocyclic derivatives.

    Veronika Pašková;Klára Hilscherová;Klára Hilscherová;Marie Feldmannová;Marie Feldmannová;Luděk Bláha;Luděk Bláha

  • Disruption of retinoid transport, metabolism and signaling by environmental pollutants.

    Jiří Novák;Martin Beníšek;Klára Hilscherová

Frequent Co-Authors

John P. Giesy
John P. Giesy University of Saskatchewan
Blahoslav Maršálek
Blahoslav Maršálek Czech Academy of Sciences
Ivan Holoubek
Ivan Holoubek Masaryk University
Beate I. Escher
Beate I. Escher Helmholtz Centre for Environmental Research
Werner Brack
Werner Brack Helmholtz Centre for Environmental Research
Branislav Vrana
Branislav Vrana Masaryk University
Henner Hollert
Henner Hollert Goethe University Frankfurt
Rolf Altenburger
Rolf Altenburger Helmholtz Centre for Environmental Research
Xiaowei Zhang
Xiaowei Zhang Nanjing University
Jana Klánová
Jana Klánová Masaryk University

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