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Molecular Biology

D-Index
48
Citations
14489
World Ranking
2661
National Ranking
1298

Overview

Benjamin P. Tu is affiliated with The University of Texas Southwestern Medical Center in the United States. Their work primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with significant contributions across multiple subfields including Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Biochemistry, and Pharmacology.

Their recent publications cover a range of topics and research areas. Notable papers include:

  • "Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence" (2020) published in Molecular Cell
  • "Glucose starvation induces a switch in the histone acetylome for activation of gluconeogenic and fat metabolism genes" (2022) published in Molecular Cell
  • "Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain" (2020) published in Proceedings of the National Academy of Sciences
  • "SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A" (2021) published in eLife
  • "Autophagy sustains glutamate and aspartate synthesis in Saccharomyces cerevisiae during nitrogen starvation" (2021) published in Nature Communications

Their research topics include:

  • RNA modifications and cancer
  • RNA Research and Splicing
  • Cancer-related gene regulation
  • RNA and protein synthesis mechanisms
  • Epigenetics and DNA Methylation
  • Polyamine Metabolism and Applications
  • Mitochondrial Function and Pathology

Benjamin P. Tu has collaborated frequently with several researchers, most notably Benjamin M. Sutter, Kuanqing Liu, Juliana N Flaherty, Olga V. Hunter, and Nicholas K. Conrad, indicating a network of close research partnerships across their studies.

Their work appears repeatedly in particular scientific venues, which include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Nature Communications
  • eLife
  • Cell Reports

Through their publications, Benjamin P. Tu contributes to ongoing developments in molecular biology and biochemistry, with a focus on the mechanisms governing RNA function, gene regulation in cancer, and cellular metabolic processes.

Best Publications

  • Oxidative protein folding in eukaryotes mechanisms and consequences

    Benjamin P. Tu;Jonathan S. Weissman

  • Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes

    Benjamin P. Tu;Andrzej Kudlicki;Maga Rowicka;Steven L. McKnight

  • The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention

    Kathryn E. Pendleton;Beibei Chen;Kuanqing Liu;Olga V. Hunter

  • Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

    Tomoyuki Mashimo;Kumar Pichumani;Vamsidhara Vemireddy;Kimmo J. Hatanpaa

  • Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

    Lei Shi;Benjamin P Tu

  • Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes

    Ling Cai;Benjamin M. Sutter;Bing Li;Benjamin P. Tu

  • Acetate dependence of tumors.

    Sarah A Comerford;Zhiguang Huang;Xinlin Du;Yun Wang

  • Biochemical Basis of Oxidative Protein Folding in the Endoplasmic Reticulum

    Benjamin P. Tu;Siew C. Ho-Schleyer;Kevin J. Travers;Jonathan S. Weissman

  • The FAD- and O2-Dependent Reaction Cycle of Ero1-Mediated Oxidative Protein Folding in the Endoplasmic Reticulum

    Benjamin P Tu;Jonathan S Weissman

  • Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.

    Isaac Marin-Valencia;Chendong Yang;Tomoyuki Mashimo;Steve Cho

  • Cyclic changes in metabolic state during the life of a yeast cell

    Benjamin P. Tu;Rachel E. Mohler;Jessica C. Liu;Kenneth M. Dombek

  • Direct Regulation of GTP Homeostasis by (p)ppGpp: A Critical Component of Viability and Stress Resistance

    Allison Kriel;Alycia N. Bittner;Sok Ho Kim;Kuanqing Liu

  • Metabolic cycles as an underlying basis of biological oscillations

    Benjamin P. Tu;Steven L. McKnight

  • Eight Kinetically Stable but Thermodynamically Activated Molecules that Power Cell Metabolism

    Christopher T. Walsh;Benjamin P. Tu;Yi Tang

  • Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity

    Zheng Chen;Elizabeth A. Odstrcil;Benjamin P. Tu;Benjamin P. Tu;Steven L. McKnight;Steven L. McKnight

  • Methionine Inhibits Autophagy and Promotes Growth by Inducing the SAM-Responsive Methylation of PP2A

    Benjamin M. Sutter;Xi Wu;Sunil Laxman;Benjamin P. Tu

  • Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation

    Sunil Laxman;Benjamin M. Sutter;Xi Wu;Sujai Kumar

  • A Metabolic Function for Phospholipid and Histone Methylation.

    Cunqi Ye;Benjamin M. Sutter;Yun Wang;Zheng Kuang

  • Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of Its Methionine-Rich Low-Complexity Domain

    Masato Kato;Yu San Yang;Benjamin M. Sutter;Yun Wang

  • Driving the cell cycle through metabolism

    Ling Cai;Benjamin P. Tu

Frequent Co-Authors

Steven L. McKnight
Steven L. McKnight The University of Texas Southwestern Medical Center
Lei Shi
Lei Shi National Institute on Drug Abuse
Ralph J. DeBerardinis
Ralph J. DeBerardinis The University of Texas Southwestern Medical Center
Jef D. Boeke
Jef D. Boeke New York University
Robert Bachoo
Robert Bachoo The University of Texas Southwestern Medical Center
David Fenyö
David Fenyö New York University
Nick V. Grishin
Nick V. Grishin The University of Texas Southwestern Medical Center
Elton T. Young
Elton T. Young University of Washington
Margaret A. Phillips
Margaret A. Phillips The University of Texas Southwestern Medical Center

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