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Molecular Biology

D-Index
98
Citations
54139
World Ranking
565
National Ranking
310

Research.com Recognitions

  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1992 - Fellow of the American Academy of Arts and Sciences
  • 1992 - Member of the National Academy of Sciences

Overview

Steven L. McKnight is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions in molecular biology and cell biology.

Throughout their career, McKnight has explored diverse topics related to RNA research, protein structure, and cellular biology. Key areas of study include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Skin and Cellular Biology Research
  • RNA regulation and disease
  • Cancer-related gene regulation

McKnight has published extensively in prominent scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Science
  • Neurology
  • Journal of Biological Chemistry

Recent papers authored or co-authored by McKnight include:

  • "Mutations linked to neurological disease enhance self-association of low-complexity protein sequences," 2022, Science
  • "Transiently structured head domains control intermediate filament assembly," 2021, Proceedings of the National Academy of Sciences
  • "Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain," 2020, Proceedings of the National Academy of Sciences
  • "How do protein domains of low sequence complexity work?", 2021, RNA
  • "Toxin-Induced Parkinsonism," 2020, Neurologic Clinics

Steven L. McKnight has collaborated frequently with other researchers. Frequent co-authors include:

  • Xiaoming Zhou
  • Masato Kato
  • Lillian B. Sutherland
  • Glen Liszczak
  • Vasiliy O. Sysoev

McKnight is recognized as a fellow of the American Association for the Advancement of Science (AAAS) since 2006 and the American Academy of Arts and Sciences since 1992. Additionally, McKnight has been a member of the National Academy of Sciences since 1992.

Best Publications

  • The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

    William H. Landschulz;Peter F. Johnson;Steven L. McKnight

  • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

    Zhaodan Cao;Robert M. Umek;Steven L. McKnight

  • Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

    Masato Kato;Tina W. Han;Shanhai Xie;Kevin Shi

  • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.

    Hui Tian;Steven L. McKnight;David W. Russell

  • Transcriptional control signals of a eukaryotic protein-coding gene

    Steven L. McKnight;Robert Kingsbury

  • Eukaryotic transcriptional regulatory proteins.

    Peter F. Johnson;Steven L. McKnight

  • Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

    Wen-Chen Yeh;Zhaodan Cao;Marie Classon;Steven L. McKnight

  • Scissors-grip model for DNA recognition by a family of leucine zipper proteins

    Charles R. Vinson;Paul B. Sigler;Steven L. McKnight

  • An interleukin-4-induced transcription factor: IL-4 Stat

    Jinzhao Hou;Ulrike Schindler;William J. Henzel;Tze Chun Ho

  • Isolation of a recombinant copy of the gene encoding C/EBP.

    William H. Landschulz;Peter F. Johnson;Eli Y. Adashi;Barbara J. Graves

  • Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

    Steven J. Triezenberg;Robert C. Kingsbury;Steven L. McKnight

  • Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors.

    Jared Rutter;Martin Reick;Leeju C. Wu;Steven L. McKnight

  • Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes

    Benjamin P. Tu;Andrzej Kudlicki;Maga Rowicka;Steven L. McKnight

  • Influence of Metabolism on Epigenetics and Disease

    William G. Kaelin;Steven L. McKnight

  • CCAAT-enhancer binding protein: a component of a differentiation switch.

    Robert M. Umek;Alan D. Friedman;Steven L. Mcknight

  • Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains

    Dylan T. Murray;Masato Kato;Yi Lin;Kent R. Thurber

  • Transcriptional selectivity of viral genes in mammalian cells.

    Steven McKnight;Robert Tjian

  • Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

    Tina W. Han;Masato Kato;Shanhai Xie;Leeju C. Wu

  • The DNA binding domain of the rat liver nuclear protein, C/EBP, is bipartite

    William H. Landschulz;Peter F. Johnson;Steven L. McKnight

  • NPAS2: An Analog of Clock Operative in the Mammalian Forebrain

    Martin Reick;Joseph A. Garcia;Carol Dudley;Steven L. McKnight

Frequent Co-Authors

Benjamin P. Tu
Benjamin P. Tu The University of Texas Southwestern Medical Center
Peter F. Johnson
Peter F. Johnson National Institutes of Health
Jef K. De Brabander
Jef K. De Brabander The University of Texas Southwestern Medical Center
Andrew A. Pieper
Andrew A. Pieper University of Iowa
Robert Tycko
Robert Tycko National Institutes of Health
Jared Rutter
Jared Rutter University of Utah
Noelle S. Williams
Noelle S. Williams The University of Texas Southwestern Medical Center
David W. Russell
David W. Russell University of Washington
Donald M. Coen
Donald M. Coen Harvard University
Barbara J. Graves
Barbara J. Graves University of Utah

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