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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
13249
World Ranking
15994
National Ranking
6643

Overview

Iswar K. Hariharan is affiliated with the University of California, Berkeley in the United States. Their research spans the fields of Biochemistry, Genetics, and Molecular Biology, with a primary focus on Molecular Biology, Cell Biology, and Cellular and Molecular Neuroscience. Other areas of study include Immunology and Genetics.

The scientist's research topics include Developmental Biology and Gene Regulation, Hippo pathway signaling and YAP/TAZ, Neurobiology and Insect Physiology Research, Wnt/β-catenin signaling in development and cancer, Single-cell and spatial transcriptomics, Invertebrate Immune Response Mechanisms, and Hedgehog Signaling Pathway Studies.

Key recent publications feature investigations into Drosophila imaginal disc regeneration, transcriptomics, and cell signaling pathways. Notable papers include:

  • Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in Drosophila, 2020, eLife
  • Single-cell transcriptomics of the Drosophila wing disc reveals instructive epithelium-to-myoblast interactions, 2021, eLife
  • Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs, 2022, Current Biology
  • Imaginal Disc Regeneration: Something Old, Something New, 2021, Cold Spring Harbor Perspectives in Biology
  • Membrane potential regulates Hedgehog signalling in the Drosophila wing imaginal disc, 2021, EMBO Reports

Frequent co-authors in their research collaborations include Melanie I. Worley, Riku Yasutomi, Nicholas J. Everetts, Nir Yosef, and Maya Emmons-Bell.

Publication venues where Iswar K. Hariharan has been active most often include bioRxiv (Cold Spring Harbor Laboratory), eLife, and Development. Contributions have also appeared in Current Biology and Cold Spring Harbor Perspectives in Biology.

Best Publications

  • Comparative Genomics of the Eukaryotes

    Gerald M. Rubin;Mark D. Yandell;Jennifer R. Wortman;George L. Gabor

  • The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell Proliferation and Promotes Apoptosis

    Kieran F. Harvey;Cathie M. Pfleger;Iswar K. Hariharan

  • salvador Promotes Both Cell Cycle Exit and Apoptosis in Drosophila and Is Mutated in Human Cancer Cell Lines

    Nicolas Tapon;Kieran F. Harvey;Daphne W. Bell;Doke C.R. Wahrer

  • The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.

    Nicolas Tapon;Naoto Ito;Barry J. Dickson;Jessica E. Treisman

  • Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

    Kenneth H. Moberg;Daphne W. Bell;Doke C. R. Wahrer;Daniel A. Haber

  • A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis.

    Joriene C de Nooij;Mary Ann Letendre;Iswar K Hariharan

  • Mutations in erupted, the Drosophila Ortholog of Mammalian Tumor Susceptibility Gene 101, Elicit Non-Cell-Autonomous Overgrowth

    Kenneth H. Moberg;Suzanne Schelble;Sharon K. Burdick;Iswar K. Hariharan

  • bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.

    A G Elefanty;I K Hariharan;S Cory

  • A Survey of Human Disease Gene Counterparts in the Drosophila Genome

    Mark E. Fortini;Marian P. Skupski;Mark S. Boguski;Iswar K. Hariharan

  • Regenerative Growth in Drosophila Imaginal Discs Is Regulated by Wingless and Myc

    Rachel K. Smith-Bolton;Melanie I. Worley;Hiroshi Kanda;Iswar K. Hariharan

  • Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila.

    Iswar K Hariharan;David Bilder

  • Rescue of a Drosophila NF1 mutant phenotype by protein kinase A

    Gregory E. Hannigan;Gregory E. Hannigan;Glenn S. Cowley;Glenn S. Cowley;Shoba Reginald;Shoba Reginald

  • Inactivation of Both foxo and reaper Promotes Long-Term Adult Neurogenesis in Drosophila

    Sarah E. Siegrist;Najm S. Haque;Chun-Hong Chen;Chun-Hong Chen;Bruce A. Hay

  • A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte-macrophage colony stimulating factor.

    G. R. Johnson;T. J. Gonda;D. Metcalf;I. K. Hariharan

  • Retinoids regulate a developmental checkpoint for tissue regeneration in Drosophila.

    Adrian Halme;Michelle Cheng;Iswar K. Hariharan

  • The Rap1 GTPase functions as a regulator of morphogenesis in vivo

    H. Asha;Nancy D. de Ruiter;Min‐Guang Wang;Iswar K. Hariharan

  • bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia.

    Hariharan Ik;Adams Jm;Cory S

  • Uncoupling cell fate determination from patterned cell division in the Drosophila eye

    Joriene C. de Nooij;Iswar K. Hariharan

  • A bcr-v-abl oncogene induces lymphomas in transgenic mice.

    I K Hariharan;A W Harris;M Crawford;H Abud

  • The Hippo Pathway

    Kieran F. Harvey;Iswar K. Hariharan

Frequent Co-Authors

Suzanne Cory
Suzanne Cory Walter and Eliza Hall Institute of Medical Research
Daniel A. Haber
Daniel A. Haber Harvard University
Jerry M. Adams
Jerry M. Adams Walter and Eliza Hall Institute of Medical Research
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute
Andre Bernards
Andre Bernards Harvard University
Nir Yosef
Nir Yosef University of California, Berkeley
David B. Wake
David B. Wake University of California, Berkeley
Warren S. Alexander
Warren S. Alexander Walter and Eliza Hall Institute of Medical Research
Bruce A. Hay
Bruce A. Hay California Institute of Technology
Mark S. Boguski
Mark S. Boguski National Institutes of Health

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