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Christian Kubisch

Christian Kubisch

D-Index & Metrics

Genetics

D-Index
75
Citations
23059
World Ranking
1894
National Ranking
140

Overview

Christian Kubisch is affiliated with Universität Hamburg in Germany and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their research spans multiple subfields, including Molecular Biology, Genetics, Pulmonary and Respiratory Medicine, Psychiatry and Mental Health, and Cardiology and Cardiovascular Medicine.

Kubisch's work addresses several main topics, such as:

  • RNA Research and Splicing
  • RNA Modifications and Cancer
  • Genomics and Rare Diseases
  • Migraine and Headache Studies
  • Genetics and Neurodevelopmental Disorders
  • Connective Tissue Disorders Research
  • Aortic Disease and Treatment Approaches

Their recent publications include notable papers published between 2020 and 2023:

  • "Germline AGO2 mutations impair RNA interference and human neurological development", 2020, Nature Communications
  • "A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine", 2020, Nature Communications
  • "Identification of 22 susceptibility loci associated with testicular germ cell tumors", 2021, Nature Communications
  • "Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology", 2020, Nature Communications
  • "Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor", 2023, Annals of Neurology

Kubisch has frequently published in venues such as:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Thoracic and Cardiovascular Surgeon
  • Human Genetics
  • The American Journal of Human Genetics

Collaborations are a significant component of Kubisch's research. Frequent coauthors include:

  • Davor Lessel
  • Maja Hempel
  • Hreinn Stefánsson
  • Jonas Denecke
  • Till Demal

The research output reflects a focus on understanding genetic and molecular mechanisms underlying neurological development, cardiovascular and connective tissue disorders, as well as rare diseases. Various methodologies intersect with clinical and genomic approaches, revealing diverse phenotypic associations relevant to disease studies across multiple medical specialties.

Best Publications

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.

    Alfredo Ramirez;André Heimbach;Jan Gründemann;Barbara Stiller

  • A Potassium Channel Mutation in Neonatal Human Epilepsy

    Christian Biervert;Björn C. Schroeder;Björn C. Schroeder;Björn C. Schroeder;Christian Kubisch;Christian Kubisch;Christian Kubisch;Samuel F. Berkovic;Samuel F. Berkovic;Samuel F. Berkovic

  • KCNQ4, a Novel Potassium Channel Expressed in Sensory Outer Hair Cells, Is Mutated in Dominant Deafness

    Christian Kubisch;Björn C Schroeder;Thomas Friedrich;Björn Lütjohann

  • Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

    Alfons Meindl;Heide Hellebrand;Constanze Wiek;Verena Erven

  • Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K + channels causes epilepsy

    Björn C. Schroeder;Christian Kubisch;Valentin Stein;Thomas J. Jentsch

  • KCNQ5, a Novel Potassium Channel Broadly Expressed in Brain, Mediates M-type Currents

    Björn C. Schroeder;Mirko Hechenberger;Frank Weinreich;Christian Kubisch

  • Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

    Bolz H;von Brederlow B;Ramírez A;Bryda Ec

  • Genome-wide association study reveals three susceptibility loci for common migraine in the general population.

    Daniel I Chasman;Markus Schürks;Markus Schürks;Verneri Anttila;Verneri Anttila;Boukje de Vries

  • Genome-wide meta-analysis identifies new susceptibility loci for migraine

    Verneri Anttila;Bendik S. Winsvold;Bendik S. Winsvold;Padhraig Gormley;Tobias Kurth

  • Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

    Anttila;Stefansson H;Kallela M;Todt U

  • Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies

    Karsten Haug;Maike Warnstedt;Alexi K Alekov;Thomas Sander

  • Mutations in the a3 subunit of the vacuolar H+-ATPase cause infantile malignant osteopetrosis

    Uwe Kornak;Ansgar Schulz;Wilhelm Friedrich;Siegfried Uhlhaas

  • Genome-wide association analysis identifies susceptibility loci for migraine without aura.

    Tobias Freilinger;Verneri Anttila;Verneri Anttila;Boukje de Vries;Rainer Malik

  • Neurofilaments in the diagnosis of motoneuron diseases: a prospective study on 455 patients

    Petra Steinacker;Emily Feneberg;Jochen Weishaupt;Johannes Brettschneider

  • Pathophysiological Mechanisms of Dominant and Recessive KvLQT1 K+ Channel Mutations Found in Inherited Cardiac Arrhythmias

    Bernd Wollnik;Björn C. Schroeder;Christian Kubisch;Hans D. Esperer

  • Cannabinoid receptor type 2 gene is associated with human osteoporosis

    Meliha Karsak;Martine Cohen-Solal;Jan Freudenberg;Agnes Ostertag

  • Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease

    Regina C. Betz;Benedikt G. H. Schoser;Dagmar Kasper;Kenneth Ricker

  • Genome-wide association analysis identifies susceptibility loci for migraine without aura

    T. Freilinger;V. Anttila;B. de Vries;R. Malik

  • Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

    V. Anttila;H. Stefansson;M. Kallela;U. Todt

Frequent Co-Authors

Peter Nürnberg
Peter Nürnberg University of Cologne
Aarno Palotie
Aarno Palotie University of Helsinki
Bernd Wollnik
Bernd Wollnik University of Göttingen
Gudrun Nürnberg
Gudrun Nürnberg University of Cologne
Jaakko Kaprio
Jaakko Kaprio University of Helsinki
Junko Oshima
Junko Oshima University of Washington
Maija Wessman
Maija Wessman University of Helsinki
Dale R. Nyholt
Dale R. Nyholt Queensland University of Technology
Daniel I. Chasman
Daniel I. Chasman Brigham and Women's Hospital
Tobias Kurth
Tobias Kurth Charité - University Medicine Berlin

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