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Biology and Biochemistry

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67
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World Ranking
8349
National Ranking
3767

Overview

William Margolin is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a significant number of publications contributing to molecular biology and genetics subfields. Their work extends into ecology, endocrinology, and infectious diseases, reflecting a broad interest in biological sciences.

Their research topics encompass various aspects of bacterial genetics and biotechnology, bacterial interactions, and molecular mechanisms of RNA and protein synthesis. Key subjects include:

  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Escherichia coli research studies
  • Bacterial biofilms and quorum sensing
  • RNA modifications and cancer

William Margolin has published extensively in several scientific venues. Their most frequent publication platforms include:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antibiotics
  • mBio
  • Journal of Bacteriology

The scientist has collaborated regularly with other researchers, most notably:

  • Begoña Monterroso
  • Silvia Zorrilla
  • Germán Rivas
  • Miguel Ángel Robles-Ramos
  • Carlos Alfonso

Recent notable publications from William Margolin include:

  • Insights into the assembly and regulation of the bacterial divisome, 2023, Nature Reviews Microbiology
  • Complete structure of the chemosensory array core signalling unit in an E. coli minicell strain, 2020, Nature Communications
  • Macromolecular Crowding, Phase Separation, and Homeostasis in the Orchestration of Bacterial Cellular Functions, 2024, Chemical Reviews
  • Targeting the Achilles Heel of FtsZ: The Interdomain Cleft, 2021, Frontiers in Microbiology
  • Assembly of bacterial cell division protein FtsZ into dynamic biomolecular condensates, 2021, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Best Publications

  • FtsZ and the division of prokaryotic cells and organelles

    William Margolin

  • Colocalization of cell division proteins FtsZ and FtsA to cytoskeletal structures in living Escherichia coli cells by using green fluorescent protein

    Xiaolan Ma;David W. Ehrhardt;William Margolin

  • Themes and variations in prokaryotic cell division

    William Margolin

  • Splitsville: structural and functional insights into the dynamic bacterial Z ring

    Daniel P. Haeusser;William Margolin

  • Genetic and Functional Analyses of the Conserved C-Terminal Core Domain of Escherichia coli FtsZ

    Xiaolan Ma;William Margolin

  • Ca2+-mediated GTP-dependent dynamic assembly of bacterial cell division protein FtsZ into asters and polymer networks in vitro.

    Xuan Chuan Yu;William Margolin

  • FtsZ ring clusters in min and partition mutants: role of both the Min system and the nucleoid in regulating FtsZ ring localization.

    Xuan Chuan Yu;William Margolin

  • Sculpting the Bacterial Cell

    William Margolin

  • FtsZ Exhibits Rapid Movement and Oscillation Waves in Helix-like Patterns in Escherichia coli

    Swapna Thanedar;William Margolin

  • The Bacteriophage T7 Virion Undergoes Extensive Structural Remodeling During Infection

    Bo Hu;William Margolin;Ian J. Molineux;Jun Liu

  • Impact of Membrane Phospholipid Alterations in Escherichia coli on Cellular Function and Bacterial Stress Adaptation.

    Veronica W Rowlett;Venkata K P S Mallampalli;Anja Karlstaedt;William Dowhan

  • Structural remodeling of bacteriophage T4 and host membranes during infection initiation

    Bo Hu;William Margolin;Ian J. Molineux;Jun Liu

  • FtsZ dynamics during the division cycle of live Escherichia coli cells.

    Qin Sun;William Margolin

  • Visualization of the type III secretion sorting platform of Shigella flexneri.

    Bo Hu;Dustin R. Morado;William Margolin;John R. Rohde

  • A gain-of-function mutation in ftsA bypasses the requirement for the essential cell division gene zipA in Escherichia coli

    Brett Geissler;Dany Elraheb;William Margolin

  • Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells

    Jun Liu;Bo Hu;Dustin R. Morado;Sneha Jani

  • LOCALIZATION OF CELL DIVISION PROTEIN FTSK TO THE ESCHERICHIA COLI SEPTUM AND IDENTIFICATION OF A POTENTIAL N-TERMINAL TARGETING DOMAIN

    Xuan Chuan Yu;Anthony H. Tran;Qin Sun;William Margolin

  • Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check.

    Nam Ky Tonthat;Stefan T Arold;Brian F Pickering;Michael W Van Dyke

  • Effects of phospholipid composition on MinD-membrane interactions in vitro and in vivo

    Eugenia Mileykovskaya;Itzhak Fishov;Xueyao Fu;Brian D. Corbin

  • Evidence for functional overlap among multiple bacterial cell division proteins: compensating for the loss of FtsK.

    Brett Geissler;William Margolin

Frequent Co-Authors

Germán Rivas
Germán Rivas Spanish National Research Council
Jun Liu
Jun Liu Yale University
William Dowhan
William Dowhan The University of Texas Health Science Center at Houston
Maria A. Schumacher
Maria A. Schumacher Duke University
John S. Parkinson
John S. Parkinson University of Utah
Miguel A. Vicente
Miguel A. Vicente University of Salamanca
Ian J. Molineux
Ian J. Molineux The University of Texas at Austin
Donald L. Court
Donald L. Court National Institutes of Health
Peter J. Christie
Peter J. Christie The University of Texas at Austin
James R. Lupski
James R. Lupski Baylor College of Medicine

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