World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
20213
World Ranking
7297
National Ranking
3343

Overview

Fanxin Long is affiliated with the Children's Hospital of Philadelphia in the United States. Their research contributions span key areas within biochemistry, genetics, molecular biology, and medicine, focusing notably on molecular biology and its intersections with oncology, genetics, cancer research, and rheumatology.

The scientist's work prominently addresses topics such as:

  • Bone health and treatments
  • Bone metabolism and diseases
  • Wnt/β-catenin signaling in development and cancer
  • Osteoarthritis treatment and mechanisms
  • Cancer, hypoxia, and metabolism
  • Cancer-related gene regulation
  • Adipose tissue and metabolism

Frequent co-authors who have collaborated extensively with Fanxin Long include:

  • Chao Song
  • Xueyang Liao
  • Fangfang Song
  • Xing Ji
  • Lutian Yao

Fanxin Long has published multiple papers in prominent venues, with notable journals appearing repeatedly. Their most frequent publication venues are:

  • eLife
  • The FASEB Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Bone Research

Among their recent publications are:

  • Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment, 2020, eLife
  • Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment, 2022, Journal of the American Chemical Society
  • Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts, 2020, Cell Reports
  • Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation, 2020, The FASEB Journal
  • Biphasic regulation of glutamine consumption by WNT during osteoblast differentiation, 2020, Journal of Cell Science

Best Publications

  • Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation

    Donald A. Glass;Peter Bialek;Jong Deok Ahn;Michael Starbuck

  • CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

    Stephan Herzig;Fanxin Long;Fanxin Long;Ulupi S. Jhala;Susan Hedrick

  • Building strong bones: molecular regulation of the osteoblast lineage

    Fanxin Long

  • Sequential roles of Hedgehog and Wnt signaling in osteoblast development

    Hongliang Hu;Matthew J. Hilton;Xiaolin Tu;Kai Yu

  • Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation.

    Fanxin Long;Xiaoyan M. Zhang;Seth Karp;Yingzi Yang;Yingzi Yang

  • Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.

    Matthew J Hilton;Xiaolin Tu;Ximei Wu;Shuting Bai

  • Development of the Endochondral Skeleton

    Fanxin Long;David M. Ornitz

  • Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

    Ximei Wu;Xiaolin Tu;Kyu Sang Joeng;Matthew J. Hilton

  • Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton

    Fanxin Long;Ung-il Chung;Shinsuke Ohba;Jill McMahon

  • Noncanonical Wnt Signaling through G Protein-Linked PKCδ Activation Promotes Bone Formation

    Xiaolin Tu;Kyu Sang Joeng;Keiichi I. Nakayama;Keiko Nakayama

  • Energy Metabolism of the Osteoblast: Implications for Osteoporosis.

    Wen-Chih Lee;Anyonya R Guntur;Fanxin Long;Clifford J Rosen

  • WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation

    Emel Esen;Jianquan Chen;Courtney M. Karner;Adewole L. Okunade

  • Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

    Wei Zou;Hideki Kitaura;Jennifer Reeve;Fanxin Long

  • Gli1 identifies osteogenic progenitors for bone formation and fracture repair

    Yu Shi;Guangxu He;Guangxu He;Wen-Chih Lee;Jennifer A. McKenzie

  • Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization.

    Matthew J. Christopher;Fulu Liu;Matthew J. Hilton;Fanxin Long

  • NOTCH1 Regulates Osteoclastogenesis Directly in Osteoclast Precursors and Indirectly via Osteoblast Lineage Cells

    Shuting Bai;Raphael Kopan;Wei Zou;Matthew J. Hilton

  • Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

    Kory J. Lavine;Andrew C. White;Changwon Park;Craig S. Smith

  • Wnt signaling and cellular metabolism in osteoblasts.

    Courtney M. Karner;Fanxin Long

  • Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

    Leilei Zhong;Lutian Yao;Lutian Yao;Robert Joel Tower;Yulong Wei;Yulong Wei

  • mTOR signaling in skeletal development and disease

    Jianquan Chen;Fanxin Long

Frequent Co-Authors

David M. Ornitz
David M. Ornitz Washington University in St. Louis
Thomas F. Linsenmayer
Thomas F. Linsenmayer Harvard Medical School
Andrew P. McMahon
Andrew P. McMahon University of Southern California
Matthew J. Silva
Matthew J. Silva Washington University in St. Louis
Steven L. Teitelbaum
Steven L. Teitelbaum Washington University in St. Louis
Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Raphael Kopan
Raphael Kopan Cincinnati Children's Hospital Medical Center
Marc Montminy
Marc Montminy Salk Institute for Biological Studies
Pere Puigserver
Pere Puigserver Harvard University
F. Patrick Ross
F. Patrick Ross Hospital for Special Surgery

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Fanxin Long

Trending Scientists

Recently Published Articles